Only the N-terminal domain of FtsK functions in cell division

Journal of Bacteriology

Volumn 180, Issue 17, 1998, Pages 4621-4627

  Draper, G Craig ^a   McLennan, Neil ^a   Begg, Ken ^a   Masters, Millicent ^a   Donachie, William D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; FTSK PROTEIN; GENE PRODUCT; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GENE; CELL DIVISION; ESCHERICHIA COLI; GENE DELETION; GENE OVEREXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0031720923     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.17.4621-4627.1998     Document Type: Article

References (29)

1. Addinall, S. G., E. Bi, and J. Lutkenhaus. 1996. FtsZ ring formation in fts mutants. J. Bacteriol. 178:3877-3884.
2. Begg, K. J., S. J. Dewar, and W. D. Donachie. 1995. A new Escherichia coli cell division gene, ftsK. J. Bacteriol. 177:6211-6222.
3. Begg, K. J., A. Takasuga, D. H. Edwards, S. J. Dewar, B. G. Spratt, H. Adachi, T. Ohta, H. Matsuzawa, and W. D. Donachie. 1990. The balance between different peptidoglycan precursors determines whether Escherichia coli cells will elongate or divide. J. Bacteriol. 172:6697-6703.
4. Bolivar, F. 1978. Construction and characterization of new cloning vehicles. III. Derivatives of plasmid pBR322 carrying unique EcoRI sites for selection of EcoRI-generated recombinant DNA molecules. Gene 4:121-136.
5. Boyle, D., M. M. Khattar, S. G. Addinall, J. Lutkenhaus, and W. D. Donachie. 1997. ftsW is an essential gene required for the onset of cell division in Escherichia coli. Mol. Microbiol. 24:1263-1273.
6. Bukau, B., and G. C. Walker. 1989. Cellular defects caused by deletion of the Escherichia coli dnaK gene indicates roles for heat shock protein in normal metabolism. J. Bacteriol. 171:2337-2346.
7. Churchward, G., D. Belin, and Y. Nagamine. 1984. A pSC101-derived plasmid which shows no sequence homology to other commonly used cloning vectors. Gene 31:165-171.
8. Dai, K., and J. Lutkenhaus. 1992. The proper ratio of FtsZ to FtsA is required for cell division to occur in Escherichia coli. J. Bacteriol. 174:6145-6151.
9. Dai, K., Y. Xu, and J. Lutkenhaus. 1993. Cloning and characterization of ftsN, an essential cell division gene in Escherichia coli, isolated as a multicopy suppressor of ftsA12(Ts). J. Bacteriol. 175:3790-3797.
10. Dewar, S. J., K. J. Begg, and W. D. Donachie. 1992. Inhibition of cell division by an imbalance in the ratio of FtsA to FtsZ. J. Bacteriol. 174:6314-6316.
11. Diez, A. A., A. Farewell, U. Nannmark, and T. Nyström. 1997. A mutation in the ftsK gene of Escherichia coli affects cell separation, stationary-phase survival, stress adaptation, and expression of the gene encoding the stress protein UspA. J. Bacteriol. 179:5878-5883.
12. Flannagan, S. E., L. A. Zitzow, Y. A. Su, and D. B. Clewell. 1994. Nucleotide sequence of the 18 kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid 32:350-354.
13. BAD promoter. J. Bacteriol. 177:4121-4130.
14. Hagège, J., J.-L. Pernodet, G. Sezonov, C. Gerbaud, A. Friedman, and M. Guérineau. 1993. Transfer functions of the conjugative integrating element pSAM2 from Streptomyces ambofaciens: characterization of a kil-kor system associated with transfer. J. Bacteriol. 175:5529-5538.
15. Hill, T. M., B. Sharma, M. Valjavec-Gratian, and J. Smith. 1997. sfi-Independent filamentation in Escherichia coli is lexA dependent and requires DNA damage for induction. J. Bacteriol. 179:1931-1939.
16. Huisman, O., and R. D'Ari. 1983. Effect of suppressors of SOS-mediated filamentation on sfiA operon expression in Escherichia coli. J. Bacteriol. 153:169-175.
17. Kendall, K. J., and S. N. Cohen. 1988. Complete nucleotide sequence of the Streptomyces lividans plasmid pIJ101 and correlation of the sequence with genetic properties. J. Bacteriol. 170:4634-4651.
18. Khattar, M. Personal communication.
19. Kohara, Y., K. Akiyama, and K. Isono. 1987. The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50:495-508.
20. Lewis, L. K., G. R. Harlow, L. A. Gregg-Jolly, and D. W. Mount. 1994. Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli. J. Mol. Biol. 241:507-523.
21. Lewis, L. K., M. E. Jenkins, and D. W. Mount. 1992. Isolation of DNA damage-inducible promoters in Escherichia coli: regulation of polB (dinA), dinG, and dinH by LexA repressor. J. Bacteriol. 174:3377-3385.
22. Liu, G. Unpublished data.
23. Liu, G., G. C. Draper, and W. D. Donachie. FtsK is a bifunctional protein involved in cell division and chromosome localisation in Escherichia coli. Mol. Microbiol., in press.
24. Masters, M., M. D. Colloms, I. R. Oliver, L. He, E. J. MacNaughton, and Y. Charters. 1993. The pcnB gene of Escherichia coli, required for ColE1 copy number maintenance, is dispensable. J. Bacteriol. 175:4405-4413.
25. McLennan, N., and M. Masters. Unpublished data.
26. Tomura, T., K. Kishino, K. Doi, T. Hara, S. Kuhara, and S. Ogata. 1993. Sporulation-inhibitory gene in pock-forming plasmid pSA1.1 of Streptomyces azureus. Biosci. Biotechnol. Biochem. 57:438-443.
27. Wu, L. J., and J. Errington. 1994. Bacillus subtilis SpoIIIE protein required for DNA segregation during asymmetric cell division. Science 264:572-575.
28. Wu, L. J., P. J. Lewis, R. Allmansberger, P. M. Hauser, and J. Errington. 1995. A conjugation-like mechanism for prespore chromosome partitioning during sporulation in Bacillus subtilis. Genes Dev. 9:1316-1326.
29. Yu, X.-C., A. H. Tran, Q. Sun, and W. Margolin. 1998. Localization of cell division protein FtsK to the Escherichia coli septum and identification of a potential N-terminal targeting domain. J. Bacteriol. 180:1296-1304.