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1
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0031883604
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Increased expression of interleukin-6 and tumor necrosis factor-α in pathologic biliary epithelial cells: In situ and culture study
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Yasoshima M, Kono N, Sugawara H, Katayanagi K, Harada K, Nakanuma Y: Increased expression of interleukin-6 and tumor necrosis factor-α in pathologic biliary epithelial cells: in situ and culture study. Lab Invest 1998, 78:89-99.
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Yasoshima, M.1
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Nakanuma, Y.6
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2
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0030829599
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Differential effect of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats
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Vos TA, Gouw ASH, Klok PA, Havinga R, van Goor H, Huitema S, et al.: Differential effect of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats. Gastroenterology 1997, 113:1323-1333.
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Vos, T.A.1
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Van Goor, H.5
Huitema, S.6
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3
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85038540176
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Interferon-γ and interleukin-1 stimulate nitric oxide production and inducible nitric oxide synthase gene expression in rat cholangiocytes
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Granato A, Calo L, Spirli C, LaRusso NF, Vianello D, Crepaldi G, Strazzabosco M: Interferon-γ and interleukin-1 stimulate nitric oxide production and inducible nitric oxide synthase gene expression in rat cholangiocytes [abstract]. Hepatology 1997, 26:396A.
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Hepatology
, vol.26
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Granato, A.1
Calo, L.2
Spirli, C.3
Larusso, N.F.4
Vianello, D.5
Crepaldi, G.6
Strazzabosco, M.7
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4
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0030725082
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New insights into cholangiocyte physiology
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Strazzabosco M: New insights into cholangiocyte physiology. J Hepatol 1997, 27:945-952.
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J Hepatol
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Strazzabosco, M.1
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5
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4243212646
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Distinct apical and basolateral Na+/H+ exchanger in isolated perfused intrahepatic bile duct segment
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Singh SK, Cavestro GM, Mennone A, Boron WF, Boyer JL: Distinct apical and basolateral Na+/H+ exchanger in isolated perfused intrahepatic bile duct segment [abstract]. Gastroenterology 1997, 112:A1348.
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Gastroenterology
, vol.112
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Singh, S.K.1
Cavestro, G.M.2
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Boron, W.F.4
Boyer, J.L.5
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6
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0030866526
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A new rat bile ductular epithelial cell culture model characterized by the appearance of polarized bile ducts in vitro
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Sirica AE, Gainey TW: A new rat bile ductular epithelial cell culture model characterized by the appearance of polarized bile ducts in vitro. Hepatology 1997, 26:537-549.
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Hepatology
, vol.26
, pp. 537-549
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Sirica, A.E.1
Gainey, T.W.2
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7
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0030952659
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Na-dependent and -independent CI/HCO3 exchange mediate cellular HCO3 transport in cultured human intrahepatic bile duct cells
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Strazzabosco M, Joplin R, Zsembery A, Wallace L, Spirli C, Fabris L. et al.: Na-dependent and -independent CI/HCO3 exchange mediate cellular HCO3 transport in cultured human intrahepatic bile duct cells. Hepatology 1997, 25:976-985.
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Hepatology
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Strazzabosco, M.1
Joplin, R.2
Zsembery, A.3
Wallace, L.4
Spirli, C.5
Fabris, L.6
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8
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0343306676
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- cotransport participates in stimulated fluid secretion in isolated polarized bile duct units from rat liver
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- cotransport participates in stimulated fluid secretion in isolated polarized bile duct units from rat liver [abstract]. Hepatology 1996, 24:149A.
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(1996)
Hepatology
, vol.24
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Singh, S.K.1
Mennone, A.2
Boyer, J.L.3
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10
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0030665203
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Aquaporin water channel in liver: Their significance in bile formation
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Marinelli RA, LaRusso NF: Aquaporin water channel in liver: their significance in bile formation. Hepatology 1997, 26:1081-1084.
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Hepatology
, vol.26
, pp. 1081-1084
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Marinelli, R.A.1
LaRusso, N.F.2
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13
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0342437068
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Gene expression and polarized distribution of membrane acid/base carriers in a differentiated rat cholangiocyte cell line (NRC-1)
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Spirli C, Granato A, Zsembery A, Okolicsanyi L, LaRusso NF, Strazzabosco M: Gene expression and polarized distribution of membrane acid/base carriers in a differentiated rat cholangiocyte cell line (NRC-1) [abstract]. J Hepatol 1997, 23:63.
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J Hepatol
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, pp. 63
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Spirli, C.1
Granato, A.2
Zsembery, A.3
Okolicsanyi, L.4
LaRusso, N.F.5
Strazzabosco, M.6
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14
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0031015968
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Cystic fibrosis transmembrane conductance regulator mediates the cyclic adenosine monophosphate-induced fluid secretion but not the inhibition of resorption in mouse gallbladder epithelium
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Peters RHPC, van Doornick JH, French PJ, Ratcliff R, Evans MJ, Colledge WH, et al.: Cystic fibrosis transmembrane conductance regulator mediates the cyclic adenosine monophosphate-induced fluid secretion but not the inhibition of resorption in mouse gallbladder epithelium. Hepatology 1997, 25:270-277. Studies in gallbladders from CFTR knockout mice showing that cAMP-induced fluid secretion involves not only the inhibition of apical NaCl reabsorption (via PKA-mediated inhibition of apical NHE-3 activity) but also activation of ion secretory processes (via CFTR). Although CFTR (-/-) gallbladders were not capable of cAMP-stimulated fluid secretion, fluid reabsorption was unaffected.
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(1997)
Hepatology
, vol.25
, pp. 270-277
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Peters, R.H.P.C.1
Van Doornick, J.H.2
French, P.J.3
Ratcliff, R.4
Evans, M.J.5
Colledge, W.H.6
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16
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0030854849
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MUCLIN expression in the cystic fibrosis transmembrane conductance regulator knockout mouse
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De Lisle RC, Petit M, Huff J, Isom KS, Agbas A: MUCLIN expression in the cystic fibrosis transmembrane conductance regulator knockout mouse. Gastroenterology 1997, 113:521-532.
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Gastroenterology
, vol.113
, pp. 521-532
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De Lisle, R.C.1
Petit, M.2
Huff, J.3
Isom, K.S.4
Agbas, A.5
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17
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0031962056
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Dysregulation of proteoglycan production by intrahepatic biliary epithelial cells bearing defective (Delta-f508) cystic fibrosis transmembrane conductance regulator
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Bhaskar KR, Turner BS, Grubman SA, Jefferson DM, LaMont JT: Dysregulation of proteoglycan production by intrahepatic biliary epithelial cells bearing defective (Delta-f508) cystic fibrosis transmembrane conductance regulator. Hepatology 1998, 27:54-61.
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Hepatology
, vol.27
, pp. 54-61
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Bhaskar, K.R.1
Turner, B.S.2
Grubman, S.A.3
Jefferson, D.M.4
LaMont, J.T.5
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18
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0031011414
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Secretin promotes osmotic water transport in rat cholangiocytes by increasing aquaporin-1 water channels in plasma membrane
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Marinelli RA, Pham L, Agre P, LaRusso NF: Secretin promotes osmotic water transport in rat cholangiocytes by increasing aquaporin-1 water channels in plasma membrane. J Biol Chem 1997, 272:12984-12988. Consistent with previous work from the same group, secretin choleresis is shown here to involve stimulation of membrane transport of AQP-1-containing vesicles.
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J Biol Chem
, vol.272
, pp. 12984-12988
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Marinelli, R.A.1
Pham, L.2
Agre, P.3
LaRusso, N.F.4
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19
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0031936197
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Secretin and vasoactive intestinal peptide receptors: Members of a unique family of G protein-coupled receptors
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Ulrich CD, Holtmann M, Miller LJ. Secretin and vasoactive intestinal peptide receptors: members of a unique family of G protein-coupled receptors. Gastroenterology 1998, 114:382-397.
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Gastroenterology
, vol.114
, pp. 382-397
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Ulrich, C.D.1
Holtmann, M.2
Miller, L.J.3
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20
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0342871628
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Hormonal regulation of electrolyte transport in biliary epithelial cells
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Edited by Alvaro D, Benedetti A, Strazzabosco M. Amsterdam: Kluwer Academic Publishers
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Alvaro D, Gigliozzi A, La Rosa T, Carli L, Furfaro S, Fraioli F, et al.: Hormonal regulation of electrolyte transport in biliary epithelial cells. In Vanishing Bile Duct Syndrome: Pathophysiology and Treatment. Edited by Alvaro D, Benedetti A, Strazzabosco M. Amsterdam: Kluwer Academic Publishers; 1997:72-81.
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, pp. 72-81
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Alvaro, D.1
Gigliozzi, A.2
La Rosa, T.3
Carli, L.4
Furfaro, S.5
Fraioli, F.6
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21
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0030979612
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Bombesin stimulates bicarbonate secretion from rat cholangiocytes: Implications for neural regulation of bile secretion
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Cho WK, Mennone A, Rydberg SA, Boyer JL: Bombesin stimulates bicarbonate secretion from rat cholangiocytes: implications for neural regulation of bile secretion. Gastroenterology 1997, 113:311-321. This study exploited a number of techniques in biliary physiology, including liver perfusion, hepatocyte couplets, and IBDU to show the possible role of neuropeptides in ductular choleresis.
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(1997)
Gastroenterology
, vol.113
, pp. 311-321
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Cho, W.K.1
Mennone, A.2
Rydberg, S.A.3
Boyer, J.L.4
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22
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0030939162
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Neuropeptide Y in the dorsal vagal complex stimulates bicarbonate-dependent bile secretion in rats
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Yoneda M, Yokohama S, Tamori K, Sato Y, Nakamura K, Makino I: Neuropeptide Y in the dorsal vagal complex stimulates bicarbonate-dependent bile secretion in rats. Gastroenterology 1997, 112:1673-1681.
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Gastroenterology
, vol.112
, pp. 1673-1681
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Yoneda, M.1
Yokohama, S.2
Tamori, K.3
Sato, Y.4
Nakamura, K.5
Makino, I.6
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23
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0030844035
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Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions
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Alvaro D, Alpini G, Jezequel AM, Bassotti C, Francia C, Fraioli F, et al.: Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions. J Clin Invest 1997, 100:1349-1362. An elegant and thorough investigation of cholinergic regulation of cholangiocyte secretion.
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J Clin Invest
, vol.100
, pp. 1349-1362
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Alvaro, D.1
Alpini, G.2
Jezequel, A.M.3
Bassotti, C.4
Francia, C.5
Fraioli, F.6
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24
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0030961763
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Muscarinic acetylcholine receptor stimulation of biliary epithelial cells and its effect on bile secretion in the isolated perfused rat liver
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Elsing E, Hübner C, Fitscher BA, Kassner A, Stremmel W: Muscarinic acetylcholine receptor stimulation of biliary epithelial cells and its effect on bile secretion in the isolated perfused rat liver. Hepatology 1997, 254:804-813.
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(1997)
Hepatology
, vol.254
, pp. 804-813
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Elsing, E.1
Hübner, C.2
Fitscher, B.A.3
Kassner, A.4
Stremmel, W.5
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27
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0342437056
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Morphological and functional heterogeneity of the rat intrahepatic biliary tree
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Edited by Alvaro D, Benedetti A, Strazzabosco M. Amsterdam: Kluwer Academic Publishers
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Alpini G, Glaser S, Rodgers R, Robertson W, Phinigy JL, Colegio O, et al.: Morphological and functional heterogeneity of the rat intrahepatic biliary tree. In Vanishing Bile Duct Syndrome: Pathophysiology and Treatment. Edited by Alvaro D, Benedetti A, Strazzabosco M. Amsterdam: Kluwer Academic Publishers; 1997:32-51. Excellent review of cholangiocyte heterogeneity.
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(1997)
Vanishing Bile Duct Syndrome: Pathophysiology and Treatment
, pp. 32-51
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Alpini, G.1
Glaser, S.2
Rodgers, R.3
Robertson, W.4
Phinigy, J.L.5
Colegio, O.6
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28
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0030900791
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Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation
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Alpini G, Ulrich C, Roberts S, Phillips JO, Ueno Y, Podila PV, et al.: Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation. Am J Physiol 1997, 272:G289-G297.
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Am J Physiol
, vol.272
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Alpini, G.1
Ulrich, C.2
Roberts, S.3
Phillips, J.O.4
Ueno, Y.5
Podila, P.V.6
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29
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0030918442
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Large but not small intrahepatic bile ducts are involved in secretin-regulated ductal bile secretion
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Alpini G, Glaser S, Robertson W, Rodgers RED, Phinizy JL, Lasater J, LeSage GD: Large but not small intrahepatic bile ducts are involved in secretin-regulated ductal bile secretion. Am J Physiol 1997, 272:G1064-G1074. Strong indication that, in rats, hormone-regulated bicarbonate secretion is a specialized function of large ducts.
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Am J Physiol
, vol.272
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Alpini, G.1
Glaser, S.2
Robertson, W.3
Rodgers, R.E.D.4
Phinizy, J.L.5
Lasater, J.6
LeSage, G.D.7
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30
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0343742160
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Human biliary ductular cells co-express NCAM and BCL-2: A marker of immature liver progenitor cells?
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Fabris L, Crosby H, Johnson GD, Strain AJ, Kelly DA, Strazzabosco M, et al.: Human biliary ductular cells co-express NCAM and BCL-2: a marker of immature liver progenitor cells? [abstract]. J Hepatol 1997,26:144.
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J Hepatol
, vol.26
, pp. 144
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Fabris, L.1
Crosby, H.2
Johnson, G.D.3
Strain, A.J.4
Kelly, D.A.5
Strazzabosco, M.6
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31
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0030858601
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Carrier-mediated transport of conjugated bile acids across the basolateral membrane of biliary epithelial cells
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Benedetti A, Di Sario A, Marucci L, Svegliati-Baroni G, Schteingart CD, Ton-Nu HT, Hofmann AF: Carrier-mediated transport of conjugated bile acids across the basolateral membrane of biliary epithelial cells. Am J Physiol 1997, 272:G1416-G1424.
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Am J Physiol
, vol.272
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Benedetti, A.1
Di Sario, A.2
Marucci, L.3
Svegliati-Baroni, G.4
Schteingart, C.D.5
Ton-Nu, H.T.6
Hofmann, A.F.7
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33
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0031467883
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Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter
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Lazaridis KN, Pham L, Tiets P, Marinelli R, De Groen PT, Levine S, et al.: Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter. J Clin Invest 1997, 100:2714-2721. Direct evidence that conjugated bile acids are taken up at the apical domain of cholangiocytes via the ileal bile acid transporter.
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J Clin Invest
, vol.100
, pp. 2714-2721
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Lazaridis, K.N.1
Pham, L.2
Tiets, P.3
Marinelli, R.4
De Groen, P.T.5
Levine, S.6
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34
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0030760489
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Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes
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Alpini G, Glaser S, Robertson W, Phinizy JL, Rodgers R, Caligiuri A, LeSage G: Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes. Am J Physiol 1997, 273:G518-G529.
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Am J Physiol
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Alpini, G.1
Glaser, S.2
Robertson, W.3
Phinizy, J.L.4
Rodgers, R.5
Caligiuri, A.6
LeSage, G.7
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35
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0343742183
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Pathophysiology of the biliary epithelium
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Edited by Alvaro D, Benedetti A, Strazzabosco M. Amsterdam: Kluwer Academic Publishers
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Strazzabosco M, Spirli C, Zsembery A, Granato A, Fabris L, Cavestro GM, et al.: Pathophysiology of the biliary epithelium. In Vanishing Bile Duct Syndrome: Pathophysiology and Treatment. Edited by Alvaro D, Benedetti A, Strazzabosco M. Amsterdam: Kluwer Academic Publishers; 1997:117-127.
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(1997)
Vanishing Bile Duct Syndrome: Pathophysiology and Treatment
, pp. 117-127
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Strazzabosco, M.1
Spirli, C.2
Zsembery, A.3
Granato, A.4
Fabris, L.5
Cavestro, G.M.6
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36
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0030767762
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Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line
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Hamois DM, Que FG, Celli A, LaRusso NF, Gores JG: Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line. Hepatology 1997, 26:884-890.
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Hepatology
, vol.26
, pp. 884-890
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Hamois, D.M.1
Que, F.G.2
Celli, A.3
LaRusso, N.F.4
Gores, J.G.5
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37
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0031014749
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Development and initial application of an in vitro model of apoptosis in rodent cholangiocytes
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Que FG, Gores GJ, LaRusso NF: Development and initial application of an in vitro model of apoptosis in rodent cholangiocytes. Am J Physiol 1997, 272:G106-G115.
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Am J Physiol
, vol.272
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Que, F.G.1
Gores, G.J.2
LaRusso, N.F.3
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