Collagenase and tissue plasminogen activator production in developing rat calvariae: Normal progression despite fetal exposure to microgravity

Calcified Tissue International

Volumn 63, Issue 5, 1998, Pages 416-422

  Davis, B A ^a   Sipe, B ^a   Gershan, L A ^a   Fiacco, G J ^a   Lorenz, T C ^a   Jeffrey, J J ^b   Partridge, N C ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Collagenase; Osteoblast; Spaceflight; Tissue plasminogen activator; Zero gravity

Indexed keywords

COLLAGENASE; PROTEINASE; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE GROWTH; CALVARIA; CONTROLLED STUDY; FETUS; IMMUNOHISTOCHEMISTRY; MICROGRAVITY; NEWBORN; NONHUMAN; OSTEOBLAST; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; SPACE FLIGHT;

NASA DISCIPLINE MUSCULOSKELETAL; NASA EXPERIMENT NUMBER 9303025; NON-NASA CENTER;

FLIGHT EXPERIMENT; MANNED; SHORT DURATION; STS-70 SHUTTLE PROJECT;

AGING; ANIMALS; BONE DEVELOPMENT; COLLAGENASES; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GESTATIONAL AGE; OSTEOGENESIS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; SKULL; SPACE FLIGHT; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0031717928     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900550     Document Type: Article

References (21)

1. Backup P, Westerlind K, Harris S, Spelsberg T, Kline B, Turner R (1994) Spaceflight results in reduced mRNA levels for tissue-specific proteins in the musculoskeletal system. Am J Physiol 266:E567-E573
2. Cann CE, Adachi RR (1983) Bone resorption and mineral excretion in rats during spaceflight. Am J Physiol 244:R327-R331
3. Jee WS, Wronski TJ, Morey E, Kimmel D (1983) Effects of spaceflight on trabecular bone in rats. Am J Physiol 244:R310-R314
4. Morey E, Baylink D (1978) Inhibition of bone formation during space flight. Science 201:1138-1141
5. Patterson-Buckendahl P, Arnaud SB, Mechanic GL, Martin RB, Grindeland RE, Cann C (1987) Fragility and composition of growing rat bone after one week in spaceflight. Am J Physiol 252:R240-R246
6. Simmons DJ, Grynpas MD, Rosenberg GD (1990) Maturation of bone and dentin matrices in rats flown on the Soviet biosatellite Cosmos 1887. FASEB J 4:29-33
7. Van Loon JJ, Bervoets DJ, Burger E, Dierdonne S, Hagen J, Semeins C, Doulavi B, Veldhuijzen J (1995) Decreased mineralization and increased calcium release in isolated fetal mouse long bones under near weightlessness. J Bone Miner Res 10:550-557
8. Vico L, Novikov V, Very J, Alexandre C (1991) Bone histomorphometric comparison of rat tibial metaphysis after 7-day tail suspension vs. 7-day spaceflight. Aviation Space Environ Med 62:26-31
9. Wronski TJ, Morey ER (1983) Effect of spaceflight on periosteal bone formation in rats. Am J Physiol 244:R305-R309
10. Wronski T, Morey-Holton E, Doty S, Maese A, Walsh C (1987) Histomorphometric analysis of rat skeleton following spaceflight. Am J Physiol 252:R252-R255
11. Westerlind KC, Turner RT (1995) The skeletal effects of spaceflight in growing rats: tissue-specific alterations in mRNA levels for TGF-beta. J Bone Miner Res 10:843-848
12. Garetto LP, Gonsalves MR, Morey ER, Durnova G, Roberts WE (1990) Preosteoblast production 55 hours after a 12.5-day spaceflight on Cosmos 1887. FASEB J 4:24-38
13. Heath JK, Atkinson S, Meikle M, Reynolds J (1984) Mouse osteoblasts synthesize collagenase in response to bone-resorbing agents. Biochim Biophys Acta 802:151-154
14. Partridge NC, Scott DK, Gcrshan LA, Omura TH, Burke JS, Jeffrey JJ, Bolander ME, Quinn CO (1993) Collagenase production by normal and malignant osteoblastic cells. In: Novak JF, McMaster JH (eds) Frontiers of osteosarcoma research. Hogrefe and Huber Publishers, Seattle, pp 269-276
15. Partridge NC, Winchester S (1996) Osteoblast proteinases. In: Principles of bone biology. Bilizekian JP, Raisz LG, Rodan GA (eds). Academic Press, San Diego, pp 207-216
16. DeSimone DP, Reddi AH (1992) Vascularization and endochondral bone development: changes in plasminogen activator activity. Orthopaed Res 10:320-324
17. He C, Wilhelm S, Pentland A, Marmer B, Grant G, Eisen A, Goldberg G (1989) Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci USA 86:2632-2636
18. Thomson B, Atkinson S, McGarrity A, Hembry R, Reynolds J, Meikle M (1989) Type I collagen degradation by mouse calvarial osteoblasts stimulated with 1,25-dihydroxyvitamin D-3: evidence for a plasminogen-plasmin-metalloproteinase activation cascade. Biochim Biophys Acta 1014:125-132
19. Leloup G, Peeters-Joris C, Delaisse J, Opdenakker G, Vaes G (1991) Tissue and urokinase plasminogen activators in bone tissue and their regulation by parathyroid hormone. J Bone Miner Res 6:1081-1090
20. Collin-Osdoby P (1994) Role of vascular endothelial cells in bone biology. J Cell Biochem 55:304-309
21. Simmons DJ, Russell JE, Winter F, Tran Van P, Vignery A, Baron R, Rosenberg GD, Walker WV (1983) Effect of spaceflight on the non-weight-bearing bones of rat skeleton. Am J Physiol 244:R319-R326