Adjuvant therapy for pancreatic cancer: Back to the future

International Journal of Radiation Oncology Biology Physics

Volumn 42, Issue 1, 1998, Pages 59-63

  Regine, William F ^a   Abrams, Ross A ^b  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; GEMCITABINE;

ARTICLE; CANCER ADJUVANT THERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; HUMAN; HUMAN CELL; HUMAN TISSUE; OUTCOMES RESEARCH; PANCREAS CANCER; PHASE 3 CLINICAL TRIAL; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RADIOSENSITIVITY; STANDARD;

ANTIMETABOLITES, ANTINEOPLASTIC; CLINICAL PROTOCOLS; CLINICAL TRIALS, PHASE III; COMBINED MODALITY THERAPY; DEOXYCYTIDINE; FLUOROURACIL; HUMANS; PANCREATIC NEOPLASMS; PANCREATICODUODENECTOMY; RADIATION-SENSITIZING AGENTS; RADIOTHERAPY DOSAGE;

EID: 0031717786     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(98)00179-5     Document Type: Article

References (38)

1. Parker, S. L.; Tong, T.; Bolden, S.; et al. Cancer statistics -1997. C A 47:8-9; 1997.
2. Douglass, H. Adjuvant therapy for pancreatic cancer. World J. Surg. 19:170-174; 1995.
3. Geer, R. J.; Brennan, M. F. Prognostic indicators for survival after resection of pancreatic adenocarcinoma. Am. J. Surg. 165:68-73; 1993.
4. Gudjonsson, B. Cancer of the pancreas: 50 years of surgery. Cancer 60:2284-2303; 1987.
5. Nitecki, S. S.; Sarr, M. G.; Colby, T. V.; van Heerden, J. A. Long-term survival after resection for ductal adenocarcinoma of the pancreas. Is it really improving? Ann. Surg. 221(1):59-66; 1995.
6. Piorkowski, R. J.; Believernicht, S. W.; Lawrence, W. Jr.; et al. Pancreatic and periampullary carcinoma: Experience with 200 patients over a 12-year period. Am. J. Surg. 143:189-193; 1982.
7. Shibamoto, Y.; Manabe, T.; Baba, M.; et al. High dose, external beam and intraoperative radiotherapy in the treatment of resectable pancreatic cancer. Int. J. Radiat. Oncol. Biol. Phys. 19:605-611; 1990.
8. Trede, M.; Chir, B.; Sceger, H. D. Survival after pancreaticoduodenectomy. Ann. Surg. 21(4):447-458; 1990.
9. Yeo, C. J.; Cameron, J. L.; Lillemoe, K. D.; Sitzman, J. V.; Hruban, R. H.; Goodman, S. N.; Dooley, W. C.; Coleman, J. A.; Pitt, H. A. Pancreaticoduodenectomy for cancer of the head of the pancreas. Two hundred and one patients. Ann. Surg. 221(6):721-733; 1995.
10. Douglass, H. O.; Strablein, D. M. Ten-year follow-up of first generation surgical adjuvant studies of the Gastrointestinal Tumor Study Group. In: Salmon, S. E., ed. Adjuvant therapy of cancer IV. Philadelphia: WB Saunders; 1990:405-415.
11. Kalser, M. H.; Ellenberg, S. S. Pancreatic cancer: Adjuvant combined radiation and chemotherapy following curative resection. Arch. Surg. 123:899-903; 1985.
12. Gastrointestinal Tumor Study Group. Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 59: 2006-2010; 1987.
13. Klinkenbijl, J. H. G.; Sahmoud, T.; van Pel, R.; Couvreur, M. L.; Veenhof, C. H. N.; Arnaud, J. P.; Hennipman, A.; Wils, J.; Jeekel, J. Radiotherapy and 5-FU after curative resection for cancer of the pancreas and peri-ampullary region: A phase III trial of the EORTC and GITCCG. (Abst #1239) Eur. J. Cancer 33(8):1997.
14. Simon, R. M. Design and analysis of clinic trials. In: DeVita, V. T.; Hellman, S.; Rosenberg, S. A., eds. Cancer: principles & practice of onology. 5th ed. Philadelphia: Lippincott-Raven; 1997:513-528.
15. Yeo, C. J.; Cameron, J. L.; Sohn, T. A.; Lillemoe, K. D.; Pitt, H. A.; Talamini, M. A.; Hruban, R. H.; Ord, S. E.; Sauter, P. K.; Coleman, J. A.; Zahurak, M. L.; Grochow, L. B.; Abrams, R. A. 650 consecutive pancreaticoduodenectomies in the 1990s: Pathology, complications, outcomes. Ann. Surg. 226(30):248-260; 1997.
16. Sohn, T. A.; Yeo, C. J.; Cameron, J. L.; Lillemoe, K. D.; Talamini, M. A.; Hruban, R. H.; Sauter, P. K.; Coleman, J. A.; Ord, S. E.; Grochow, L. B.; Abrams, R. A.; Pitt, H. A. Should pancreaticoduodenectomy be performed in octogenarians? J. Gastrointest. Surg. 2(3):207-216, 1998.
17. Lillemoe, K. D.; Cameron, J. L.; Yeo, C. J.; Sohn, T. A.; Nakeeb, A.; Sauther, P. K.; Hruban, R. H.; Abrams, R. A.; Pitt, H. A. Pancreaticoduodenectomy: Does it have a role in the palliation of pancreatic cancer? Ann. Surg. 223(6):717-728; 1996.
18. Abrams, R. A.; Grochow, L. B. Adjuvant therapy with chemotherapy and radiation therapy in the management of carcinoma of the pancreatic head. Surg. Clin. North Am. 75(5): 925-938; 1995.
19. Allema, J. H.; Reinders, M. E.; van Gulik, T. M.; Koelemay, M. J. W.; van Leeuwen, D. J.; Laurens, T. d. W.; Gouma, D. J.; Obertop, H. Prognostic factors for survival after pancreaticoduodenectomy for patients with carcinoma of the pancreatic head region. Cancer 75:2069-2076; 1995.
20. Bottger, T. C.; Storkel, S.; Wellek, S.; Stockle, M.; Junginger, T. Factors influencing survival after resection of cancer: A DNA analysis and a histomorphologic study. Cancer 73(1): 63-73; 1993.
21. Willett, C. G.; Lewandrowski, K.; Warshaw, A. L.; Efird, J.; Compton, C. C. Resection margins in carcinoma of the head of the pancreas: Implications for radiation therapy. Ann. Surg. 217(2):144-148; 1993.
22. Yeo, C. J.; Abrams, R. A.; Crochow, L. B.; Sohn, T. A.; Ord, S. E.; Hruban, R. H.; Zahurak, M.; Dooley, W. C.; Coleman, J. A.; Sauter, P. K.; Pitt, H. A.; Lillemoe, K. D.; Cameron, J. L. Pancreaticoduodenectomy for pancreatic adenocarcinoma: Postoperative adjuvant chemoradiation improves survival: A prospective, single-institution experience. Ann. Surg. 225(5):621-636; 1997.
23. Foo, M. L.; Gunderson, L. L.; Nagorney, D. M.; McLirath, D. C.; van Heerden, J. A.; Robinow, J. S.; Kvols, L. K.; Garton, G. R.; Martenson, J. A.; Cha, S. S. Patterns of failure in grossly resected pancreatic ductal adenocarcinoma treated with adjuvant irradiation ± 5-fluorouracil. Int. J. Radiat. Oncol. Biol. Phys. 26:483-489; 1993.
24. Mohiuddin, M.; Rosato, F.; Schuricht, A.; Barbot, D.; Biermann, W.; Cantor, R. Carcinoma of the pancreas - The Jefferson experience 1975-1988. Eur. J. Surg. Oncol. 20:13-20; 1994.
25. Yeo, C. J.; Hruban, R. H.; Kern, S. E.; Abrams, R. A.; Grochow, L. B.; Griffin, C. A.; Cameron, J. L. Adenocarcinoma of the pancreas: Factors influencing outcome after pancreaticoduodenectomy - The Johns Hopkins experience. Cancer Bull. 46(6):504-510; 1994.
26. O'Connell, M. J.; Martenson, M. A.; Wieand, H. S.; Krook, J. E.; MacDonald, J. S.; Haller, D. G.; Mayer, R. J.; Gunderson, L. L.; Rich, T. A. Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N. Engl. J. Med. 331(8): 502-507; 1994.
27. Spitz, F. R.; Abbruzzese, J. L.; Lee, J. E.; Pisters, P. W. T.; Lowy, A. M.; Fenoglio, C. J.; Cleary, K. R.; Janjan, N. A.; Goswitz, M. S.; Rich, T. A.; Evans, D. B. Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas. J. Clin. Oncol. 15(3):928-937; 1997.
28. Whittington, R.; Neuberg, D.; Tester, W. J.; Benson, A. B.; Haller, D. G. L. Protracted intravenous fluorouracil infusion with radiation therapy management of localized pancreaticobiliary carcinoma: A phase I Eastern Cooperative Group trial. J. Clin. Oncol. 13(1):227-232; 1995.
29. Davis, B. J.; Raben, A.; Casper, E.; Minsky, B. D. Acute toxicity and efficacy of postoperative combined modality therapy for adenocarcinoma of the pancreas. Proceedings of the 38th Annual ASTRO Meeting, (Abst #2039). Int. J. Radiat. Oncol. Biol. Phys. 36(1):297; 1996.
30. Regine, W. F.; John, W. J.; Strodel, W. E.; Mohiuddin, M. Dose-intensive chemoradiation following pancreaticoduodenectomy for pancreatic carcinoma - A phase I study. Proceedings of the 38th Annual ASTRO Meeting, (Abstr. #2042). Int. J. Radiat. Oncol. Biol. Phys. 36(1):299; 1996.
31. Burris, H. A.; Moore, M. J.; Anderson, J.; Green, M. R.; Rothenberg, M. L.; Modiano, M. R.; Cripps, M. C.; Portenoy, R. K.; Storniolo, A. M.; Tarassoff, P.; Nelson, R.; Door, F. A.; Stephens, C. D.; von Hoff, D. D. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J. Clin. Oncol. 15(6):2403-2413; 1997.
32. Rothenberg, M. L.; Moore, M. J.; Cripps, M. C.; Andersen, J. S.; Portenoy, R. K.; Burris, H. A. III; Green, M. R.; Tarassoff, P. G.; Brown, T. D.; Casper, E. S.; Storniolo, A. M.; von Hoff, D. D. A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer. Ann. Oncol. 7:347-353; 1996.
33. Peters, L. J.; Goepfert, H.; Ang, K. K.; Byers, R. M.; Maor, M. H.; Gullamondegui, D.; Morrison, W. H.; Weber, R. S.; Garden, A. S.; Frankenthaler, R. A.; Oswald, M. J.; Brown, B. W. Evaluation of the dose for postoperative radiation therapy of head and neck cancer: First report of a prospective randomized trial. Int. J. Radiat. Oncol. Biol. Phys. 26:3-9; 1993.
34. Gianni, A. M.; Siena, S.; Bregni, M.; DiNicola, M.; Orefice, S.; Cusumano, F.; Salvadori, B.; Luini, A.; Greco, M.; Zucali, R.; Rilke, F.; Zambetti, M.; Valagussa, P.; Bonadonna, G. Efficacy, toxicity, and applicability of high dose sequential chemotherapy as adjuvant treatment in operable breast cancer with 10 or more involved axillary nodes: Five year results. J. Clin. Oncol. 15:2312-2321; 1997.
35. Tepper, J. R.; O'Connell, M. J.; Petroni, G. R.; Hollis, D.; Cooke, E.; Benson, A. B. III; Cummings, B.; Gunderson, L. L.; MacDonald, J. S.; Martenson, J. A. Adjuvant postoperative fluorouracil modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: Initial results of intergroup 0114. J. Clin. Oncol. 15:2030-2039; 1997.
36. Zaniboni, A. Adjuvant chemotherapy on colorectal cancer with high dose leucovorin and fluorouracil: Impact on disease free survival and overall survival. J. Clin. Oncol. 15:2432-2441; 1997.
37. DeVita, V. T. Principles of cancer management: Chemotherapy. In: DeVita, V. T.; Hellman, S.; Rosenberg, S. A., eds. Cancer: Principles and practice of oncology, 5th ed. 333-347; 1997.
38. Foa, R.; Guarini, A.; Cignetti, A.; Cronin, K.; Rosenthal, F.; Gansbacher, B. Cytokine gene therapy: A new strategy for the management of cancer patients. Nat. Immun. 13:65-75; 1994.