Evaluation of muscle oxidative potential by 31P-MRS during incremental exercise in old and young humans

European Journal of Applied Physiology and Occupational Physiology

Volumn 78, Issue 5, 1998, Pages 460-465

  Chilibeck, Philip D ^a,b,c   McCreary, Cheryl R ^a,b   Marsh, Greg D ^a,b   Paterson, Donald H ^a,b   Noble, Earl G ^d   Taylor, Albert W ^d   Thompson, R Terry ^a,b  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d University of Saskatchewan ^*

Author keywords

31P MRS; Ageing; Citrate synthase; Lateral gastrocnemius; Oxidative capacity

Indexed keywords

CITRATE SYNTHASE; CREATINE PHOSPHATE; PHOSPHATE;

ADULT; AGED; ANKLE; ARTICLE; CELL PH; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE; FEMALE; GASTROCNEMIUS MUSCLE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; METABOLISM; MUSCLE; MUSCLE BIOPSY; MUSCLE TYPE ACCORDING TO FUNCTION; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION POTENTIAL; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; WORK CAPACITY;

ADULT; AGE FACTORS; AGED; AGING; BIOPSY; CITRATE (SI)-SYNTHASE; EXERTION; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MUSCLE FIBERS; MUSCLE, SKELETAL; OXYGEN CONSUMPTION; PHOSPHORUS ISOTOPES;

EID: 0031716674     PISSN: 03015548     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004210050446     Document Type: Article

References (42)

1. 31P-NMR spectroscopy and the metabolic properties of different muscle fibres. J Appl Physiol 68:644-649
2. Anuola S, Marniemi J, Alanen E, Mantyla M, Saraste M, Rusko H (1988) Muscle metabolic profile and oxygen transport capacity as determinants of aerobic and anaerobic thresholds. Eur J Appl Physiol 57:726-734
3. Barstow TJ, Buchthal SD, Zanconato S, Cooper DM (1994) Changes in potential controllers of human skeletal muscle respiration during incremental calf exercise. J Appl Physiol 77:2169-2176
4. Bendahan D, Confort-Gouny S, Kozak-Reiss G, Cozzone PJ (1990) Heterogeneity of metabolic response to muscular exercise in humans. FEBS Lett 272:155-158
5. Brooke MH, Kaiser KK (1970) Three "myosin ATPase" systems: The nature of their pH lability and sulfhydryl dependence. J Histochem Cytochem 18:670-672
6. Chance B, Eleff S, Bank W, Leigh JS, Warnell R (1982) 31-P NMR studies of control of mitochondrial function in phosphofructokinase-deficient human skeletal muscle. Proc Natl Acad Sci USA 79:7714-7718
7. Coggan AR, Spina RJ, King DS, Rogers MA, Brown M, Nemeth PM, Holloszy JO (1992a) Skeletal muscle adaptations to endurance training in 60- to 70-yr-old men and women. J Appl Physiol 72:1780-1786
8. Coggan AR, Spina RJ, Rogers MA, King DS, Brown M, Nemeth PM, Holloszy JO (1992b) Histochemical and enzymatic comparison of the gastrocnemius muscle of young and elderly men and women. J Gerontol 47:B71-B76
9. Davis JA, Whipp BJ, Lamarra N, Huntsman DJ, Frank MH, Wasserman K (1982) Effect of ramp slope on determination of aerobic parameters from the ramp exercise test. Med Sci Sports Exerc 14:339-343
10. Iotti S, Funicello R, Zaniol P, Barbiroli B (1991) The rate of phosphate transport during recovery from muscular exercise depends on cytosolic [H+]. Biochem Biophys Res Commun 178:871-877
11. Keh-Evans L, Rice CL, Noble EG, Paterson DH, Cunningham DA, Taylor AW (1992) Comparison of histochemical, biochemical and contractile properties of triceps surae of trained aged subjects. Can J Aging 11:412-425
12. Kemp GJ, Taylor DJ, Styles P, Radda GK (1993a) The production, buffering and efflux of protons in human skeletal muscle during exercise and recovery. NMR Biomed 6:73-83
13. Kemp GJ, Taylor DJ, Thompson CH, Hands LJ, Rajagopalan B, Styles P, Radda GK (1993b) Quantitative analysis by 31-P magnetic resonance spectroscopy of abnormal mitochondrial oxidation in skeletal muscle during recovery from exercise. NMR Biomed 6:302-310
14. Kemp GJ, Hands LJ, Ramaswami G, Taylor DJ, Nicolaides A, Amato A, Radda GK (1995) Calf muscle mitochondrial and glycogenolytic ATP synthesis in patients with claudication due to peripheral vascular disease analysed using. 31-P magnetic resonance spectroscopy. Clin Sci 89:581-590
15. Kent-Braun JA, Miller RG, Weiner MW (1993) Phases of metabolism during progressive exercise to fatigue in human skeletal muscle. J Appl Physiol 75:573-580
16. Lewis SF, Haller RG, Cook JD, Nunnally RL (1985) Muscle fatigue in McArdle's disease studied by 31P-NMR: effect of glucose infusion. J Appl Physiol 59:1991-1994
17. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
18. Marsh GD, Paterson DH, Thompson RT, Driedger AA (1991) Coincident thresholds in intracellular phosphorylation potential and pH during progressive exercise. J Appl Physiol 71:1076-1081
19. Marsh GD, Paterson DH, Thompson RT, Cheung PK, MacDermid J, Arnold JMO (1993) Metabolic adaptations to endurance training in older individuals. Can J Appl Physiol 18:366-378
20. McCreary CR, Chilibeck PD, Marsh GD, Paterson DH, Thompson RT (1996) Kinetics of pulmonary oxygen uptake and muscle phosphates during moderate intensity calf exercise. J Appl Physiol 81:1331-1338
21. McCully KK, Boden BP, Tuchler M, Fountain MR, Chance B (1989) Wrist flexor muscle of elite rowers measured with magnetic resonance spectroscopy. J Appl Physiol 67:926-932
22. McCully K, Vanderborne K, Walter G, Posner J, Leigh J (1992) Comparison of muscle metabolism between the lateral and medial gastrocnemius. FASEB J 6:A963
23. McCully KK, Fielding RA, Evans WJ, Leigh JS, Posner JD (1993) Relationships between in vivo and in vitro measurements of metabolism in young and old human calf muscles. J Appl Physiol 75:813-819
24. 2 saturation and PCr Kinetics after exercise in normal humans. J Appl Physiol 77:5-10
25. Meredith CN, Frontera WR, Fisher EC, Hughes VA, Herland JC, Edwards J, Evans WJ (1989) Peripheral effects of endurance training in young and old subjects. J Appl Physiol 66:2844-2849
26. 31P-NMR spectroscopy, rsEMG, and histochemical fibre types of human wrist flexor muscles. J Appl Physiol 76:531-538
27. Paganini AT, Foley JM, Meyer RA (1997) Linear dependence of muscle phosphocreatine kinetics on oxidative capacity. Am J Physiol 272:C501-C510
28. Potwarka J, Drost DJ, Williamson PC (1995) Time domain quantification of P-31 brain spectra. Proceedings of the Society of Magnetic Resonance, 3rd meeting, Nice, France, p 1986
29. Ross BD, Radda GK, Gadian DG, Rocker G, Esiri M, Falconer-Smith J (1981) Examination of a case of suspected McArdle's syndrome by 31-P nuclear magnetic resonance. N Engl J Med 304:1338-1342
30. Srere PA (1969) Citrate synthase. Methods Enzymol 13:3-8
31. Sugden PH, Newsholme EA (1975) The effects of ammonium, inorganic phosphate and potassium ions on the activity of phosphofructokinases from muscle and nervous tissues of vertebrates and invertebrates. Biochem J 150:113-122
32. 31P nuclear magnetic resonance spectroscopy study of the anaerobic threshold in humans. J Appl Physiol 68:2060-2066
33. Taylor DJ, Bore PJ, Styles P, Gadian DG, Radda GK (1983) Bioenergetics of intact human muscle: a P nuclear magnetic resonance study. Mol Biol Med 1:77-94
34. Taylor DJ, Styles P, Matthews PM, Arnold DA, Gadian DG, Bore P, Radda GK (1986) Energetics of human muscle: exercise-induced ATP depletion. Mag Reson Med 3:44-54
35. Taylor DJ, Kemp GJ, Thompson CH, Radda GK (1997) Ageing: effects on oxidative function of skeletal muscle in vivo. Mol Cell Biochem 174:321-324
36. Thomas SG, Cunningham DA, Thompson J, Rechnitzer PA (1985) Exercise training and "ventilatory threshold" in elderly. J Appl Physiol 59:1472-1476
37. Thompson CH, Kemp GJ, Radda G (1995) Triiodothyronine-induced changes in proton efflux from rat skeletal muscle in vivo. Eur J Endocrinol 133:260-264
38. Thompson RT, Muirhead N, Marsh GD, Gravelle D, Potwarka JJ, Driedger AA (1996) Effect of anaemia correction on skeletal muscle metabolism in patients with end-stage renal disease: 31-P magnetic resonance spectroscopy assessment. Nephron 73:436-441
39. Vanderborne K, McCully K, Kakihira H, Prammer M, Bolinger L, Detre JA, De Meirleir K, Walter G, Chance B, Leigh JS (1991) Metabolic heterogeneity in human calf muscle during maximal exercise. Proc Natl Acad Sci USA 88:5714-5718
40. 31P NMR signals using the variable projection method and prior knowledge. Mag Reson Med 6:92-98
41. Whipp BJ, Davis JA, Torres F, Wasserman K (1981) A test to determine parameters of aerobic function during exercise. J Appl Physiol 50:217-221
42. 31P-magnetic resonance spectroscopy of leg muscle metabolism during exercise in children and adults. J Appl Physiol 74:2214-2218