Cell-substratum interactions as a predictor of cytotoxicity

In Vitro and Molecular Toxicology: Journal of Basic and Applied Research

Volumn 11, Issue 2, 1998, Pages 183-192

  Keese, Charles R ^a,c   Karra, Narayan ^a   Dillon, Bridget ^a   Goldberg, Alan M ^b   Giaever, Ivar ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c Applied BioPhysics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZALKONIUM CHLORIDE; DODECYL SULFATE SODIUM; POLYSORBATE 20; TRITON X 100;

ANIMAL CELL; ARTICLE; BIOSENSOR; CELL CULTURE; CELL INTERACTION; CELL MOTILITY; CELL MOTION; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; ELECTRODE; EPITHELIUM CELL; FIBROBLAST; MONOLAYER CULTURE; NONHUMAN;

EID: 0031716119     PISSN: 10979336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. ALBRECHT-BUEHLER, A. (1977). The Phagokinetic Tracks of 3T3 Cells. Cell 11, 395-404.
2. BEVERLEY, C.L., HIGGINS, P.J., and BORENFREUND, E. (1984). Exp. Cell Biol. 52, 170-175.
3. BORENFREUND, E., and PUERNER, J.A. (1986). Cytotoxicity of metals, metal-metal and metal-chelator combinations assayed in vitro. Toxicology 39, 121-134.
4. GHOSH, P.M., KEESE, C.R., and GIAEVER, I. (1994). Morphological response of mammalian cells to pulsed ac fields. Bioelectrochemistry and Bioenergetics 33, 121-133.
5. GIAEVER, I., and KEESE, C.R. (1984). Monitoring fibroblast behavior in tissue culture with an applied electric field. PNAS USA 81, 3761-3764.
6. GIAEVER, I., and KEESE, C.R. (1986). Use of electric fields to monitor the dynamical aspects of cell behavior in tissue culture. IEEE Trans. Biomed. Eng. 33, 242-247.
7. GIAEVER, I., and KEESE, C.R. (1991). Micromotion of mammalian cells measured electrically. PNAS USA 88, 7896-7900.
8. GIAEVER, I., and KEESE, C.R. (1992). Toxic?, Cells can tell: Chemtech, 116-125.
9. GIAEVER, I., and KEESE, C.R. (1993). A morphological biosensor for mammalian cells Nature 366, 591-592.
10. JUMBLATT, M.M., SIMMONS, S.J., and NEUFELD, A.H. (1987). Corneal epithelial wound closure: A tissue culture model of ocular irritancy, in: In Vitro Toxicology: Approaches to Validation. A. Goldberg (ed.), Mary Ann Liebert; New York, NY pp. 139-145.
11. KEESE, C.R., and GIAEVER, I. (1994). A biosensor that monitors cell morphology with electrical fields. IEEE Eng. Med. Biol., 401-408.
12. KNOX, P., UPHILL, P.F., FRY, J.R., BEAFORD, J., and BALLS, M. (1986). Food Chem. Toxicol. 24(6), 457-463.
13. LO, C.M., KEESE, C.R., and GIAEVER, I. (1993). Monitoring motion of confluent cells in tissue culture. Exp. Cell Res. 204, 102-109.
14. MAILE, W., LINDL, T., and WEISS, D.G. (1987). New methods for cytotoxicity testing: Quantitative video microscopy of intracellular motion and mitochondria-specific fluorescence. Mol. Toxicol. 1(4), 427-437.
15. NOBEL, P.B., and LEVINE, M.D. (1986). Computer-Assisted Analysis of Cell Locomotion and Chemotaxis. CRC Press, Boca Raton, FL.
16. OSBORNE, R., and PERKINS, M.A. (1991). In vitro toxicology: Mechanisms and new technology, Vol. 8, A. Goldberg, (ed.), Mary Ann Liebert, New York, NY. pp. 317-324.
17. PARCE, J.W., OWICKE, J.C., KERCSO, K.M., SIGAL, G.B., WADA, H.G., MUIR, V.C., BOUSSE, L.J., ROSS, K.L., SIKIC, B.I., and MCCONNELL, H.M. (1989). Detection of cell-affecting agents with a silicon biosensor, Science 246, 243-247.
18. PASTERNAK, A.S., and MILLER, W.M. (1996). Measurement of trans-epithelial electrical resistance in perfusion: Potential application for in vitro ocular toxicity testing. Biotech. and Bioeng. 50, 568-579.
19. SHOPSIS, C., BORENFREUND, E., and STARK, D.M. (1987). Validation studies on a battery of potential in vitro alternatives to the Draize test, in: In vitro Toxicology - Approaches to Validation. A. Goldberg (ed.), Mary Ann Liebert; New York, NY. pp. 31-44.
20. WEISS, D.G. (1987). Videomicroscopic measurements of living cells: Dynamic determination of multiple end points for invitro toxicology. Mol. Toxicol. 1(4), 465-488.