Cross-reactive HIV-1-specific CTL in recent seroconverters from Pune, India

Indian Journal of Medical Research

Volumn 108, Issue AUG., 1998, Pages 35-41

  Paranjape, Ramesh S ^a   Gadkari, Deepak A ^d   Lubaki, Michel ^b   Quinn, Thomas C ^b,c   Bollinger, Robert C ^b  

^a NATIONAL AIDS RESEARCH INSTITUTE   (India)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d NATIONAL INSTITUTE OF VIROLOGY   (India)

Author keywords

Cytolytic T lymphocyte (CTL); Immunotype; Limiting dilution analysis (LDA); Precursor frequency; Subtype C

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

ARTICLE; CLINICAL ARTICLE; CROSS REACTION; CYTOTOXIC T LYMPHOCYTE; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INDIA; MALE; SEROCONVERSION; VIRUS IMMUNITY; VIRUS LOAD;

CROSS REACTIONS; FEMALE; GENE PRODUCTS, GAG; HIV-1; HUMANS; MALE; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0031715807     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Graham BS, Wright PF. Candidate AIDS vaccines. N Engl J Med 1995; 333 : 1331-9.
2. Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, et al. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994; 68 : 4650-5.
3. Gadkari DA, Moore D, Sheppard HW, Kulkarni SS, Mehendale SM, Bollinger RC. Transmission of genetically diverse strains of HIV-1 in Pune, Indian. India J Med Res 1998; 107 : 1-9.
4. Mulder J, McKinney N, Christerpherson C, Sninsky J, Greenfield L, Kwok S. A rapid and simple PCR assay for quantification of HIV RNA : application to acute retroviral infection. J Clin Microbiol 1994; 32 : 292-300.
5. Delwart EL, Shpaer EG, Louwagie J, McCutchan FE, Grez M, Rubsamen-Waigmann H, et al. Genetic relationships determined by a DNA heteroduplex mobility assay : analysis of HIV-1 env genes. Science 1993; 262 : 1257-61.
6. Delwart EL, Herring B, Learn GH, Rodrigo AG, Mullins JI. Heteroduplex mobility analysis HIV-1 env Subtyping kit. Protocol Version 3. Catelogue of NIH AIDS Research and Reference Reagent Program 1995; Rockville, MD, USA.
7. Tosato G. Generation of Epstein-Barr virus (EBV)Immortalized B cell lines. In : Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, editors, Current in Protocols in Immunology. Current Protocols 1994 : 1-3.
8. Lubaki MN, Egan MA, Siliciano RF, Weinhold KJ, Bollinger RC. A novel method for detection and ex vivo expansion of HIV type 1-specific cytolytic T lymphocytes. AIDS Res Hum Retroviruses 1994; 10 : 1427-31.
9. Huang XL, Fan Z, Liebmann J, Rinaldo C. Detection of human immunodeficiency virus type-1 -specific memory cytotoxic T lymphocytes in freshly donated and frozen-thawed peripheral blood mononuclear cells. Clin Diagn Lab Immunol 1995; 2 : 678-84.
10. Walker BD, Chakrabarti S, Moss B, Paradis TJ, Flynn T, Durno AG, et al. HlV-specific cytotoxic T lymphocytes in seropositive individuals. Nature 1987; 328 : 345-8.
11. Hoffenbach A, Langlade-Demoyen P, Dadaglio G, Vilmer E, Michel F, Mayaud C, et al. Unusually high frequencies of HlV-specific cytotoxic T lymphocytes in humans. J Immunol 1989; 142: 452-62.
12. Fazekas de ST, Groth S. The evaluation of limiting dilution assays. J Immunol Methods 1982; 49 : R11-23.
13. Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MBA. Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994; 68 : 6103-10.
14. Luzuriaga K, Holmes D, Hereema A. Wong J, Panicali DL, Sullivan JL. HIV-1 -specific cytotoxic T lymphocyte responses in the first year of life. J Immunol 1995; 154 : 433-43.
15. Carmichael A, Jin X, Sissons P, Borysiewicz L. Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1) specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection : differential CTL responses to HIV1 and Epstein-Barr viras in late disease. J Exp Med 1993; 177 : 249-56.
16. McFarland EJ, Harding PA, Luckey D, Conway B, Young RK, Kuritzkes DR. High frequency of gag-and envelope-specific cytotoxic T lymphocyte precursors in children with vertically acquired human immunodeficiency virus type I infection. J Infect Dis 1994; 170 : 766-74.
17. Rowland-Jones S, Sutton J, Ariyoshi K, Dong T, Gotch F, McAdam S, et al. HIV-specific cytotoxic T-cells in HIVexposed but uninfected Gambian women. Nature Med 1995; 1 : 59-64.
18. Cao H, Kanki P, Sankale JL, Dieng-Sarr A, Mazzara GP, Kalams S, et al. Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades : implications for vaccine development. J Virol 1997; 71 : 8615-23.
19. Jamieson BD, Aldrovandi GM, Planelles V, Jowett JBM, Gao L, Bloch LM, et al. Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity. J Virol 1994; 68 : 3478-85.
20. Ferrari G, Humphrey W, McElrath MJ, Excler JL, Duliege AM, Clements ML, et al. Clade B based HIV-1 vaccines elicite cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers. Proc Natl Acad Sci USA 1997; 94 : 1396-401.