Investigation of the effect of theophylline administration on total, free, short-chain acyl and long-chain acyl carnitine distributions in rat renal tissues

Cell Biochemistry and Function

Volumn 16, Issue 3, 1998, Pages 165-171

  Alhomida, A S ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Acylcarnitine; Carnitine; Kidney; Lipolysis; Rat; Theophylline

Indexed keywords

ACYLCARNITINE; CARNITINE; THEOPHYLLINE;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FATTY ACID OXIDATION; KIDNEY PARENCHYMA; LIPID TRANSPORT; LIPOLYSIS; MALE; MITOCHONDRION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ACYLATION; ANIMALS; CARNITINE; FATTY ACIDS; KIDNEY; MALE; RATS; RATS, WISTAR; THEOPHYLLINE; TIME FACTORS;

ANIMALIA;

EID: 0031715123     PISSN: 02636484     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0844(199809)16:3<165::AID-CBF782>3.0.CO;2-2     Document Type: Article

References (41)

1. Bieber, L. L. (1988). Carnitine. Ann. Rev. Biochem., 57, 261-283.
2. Hoppel, C. (1992). The physiological role of L-carnitine. In: L-Carnitine and its Role in Medicine: from Functions to Therapy. (Ferrari, R., DiMauro, S. and Sherwood, G., eds.) Academic Press: California, pp. 5-19.
3. Lysiak, W., Toth, P. P., Swelter, C. H. and Bieber, L. L. (1986). Quantitation of the afflux of acylcarnitine from rat heart, brain and liver mitochondria. J. Biol. Chem., 261, 13698-13703.
4. Alhomida, A. S., Duhaiman, A. S., Al-Jafari, A. A. and Junaid, M. A. (1995). Determination of L-carnitine, acylcarnitine and total carnitine levels in plasma and tissues of camel (Camelus dromedarius). Comp. Biochem. Physiol., 111B, 441-445.
5. Al-Eissa, M. S. and Alhomida, A. S. (1997). A study of the distribution of total, free, short-chain acyl and long-chain acyl carnitine in whole-blood and plasma of Arabian sand gazelles (Gazella subgutturosa marica). Comp. Haematol. Int., 1, 65-69.
6. Alhomida, A. S., Al-Jafari, A. A., Junaid, M. A., Al-Whaiby, S. A. and Duhaiman, A. S. (1995). Age, sex and diabetes-related changes in total, free and acylcarnitine in human plasma. Med. Sci. Res., 23, 167-169.
7. Alhomida, A. S., Duhaiman, A. S., Al-Jafari, A. A., Sobki, S., Al-Sulaiman, M. and Al-Khadar, A. (1996). Serum total, free and acyl carnitine concentrations in chronic glomerulonephritis patients. Med. Sci, Res., 24, 495-498.
8. Alhomida, A. S. (1997). Effect of chronic renal hemodialysis on serum total, free and acyl carnitine concentrations in adult chronic pyelonephritis patients. Arch. Med. Res., 28, 101-107.
9. Alhomida, A. S., Sobki, S. H., Al-Sulaiman, M. H. and Al-Khadar, A. A. (1997). Influence of gender and chronic hemodialysis treatment on total, free and acyl carnitine concentrations in human serum. Int. Urol. Nephrol., 29, 479-487.
10. Bohles, H., Evangeliou, A., Bervoets, K., Eckert, I. and Sewell, A. (1994). Carnitine esters in metabolic diseases. Eur. J. Pediatr., 153, 557-561.
11. Aranda, J. V. and Turmen, T. (1979). Methylxanthines in apnea of prematurity. Clin. Perinatol., 6, 87-107.
12. Jacobs, M. H., Senior, R. M. and Kessler, G. (1976). Clinical experience with theophylline. Relationship between dosage, serum concentration and toxicity J. Am. Med. Assoc., 235, 1983-1986.
13. Woo, O. F., Pond, S. M., Benowitz, N. J. and Olson, K. R. (1984). Benefit of hemoperfusion in acute theophylline intoxication. Clin. Toxicol., 22, 411-424.
14. Supinski, G. S., Chandler, D. and Kelson, S. G. (1984). The effects of caffeine and theophylline on diaphragm contractility. Am. Rev. Respir. Des., 130, 429-433.
15. Rall, T. W (1985). Central nervous system stimulants: the methylxanthines. In: The Pharmacological Basis of Therapeutics. (Gilman, A. G., Goodman, L. S., Rall, T. W. and Murad, F., eds.) MacMillan Publishing Co: New York, pp. 589-595.
16. Scotini, E., Carpenedo, F. and Fassina, G. (1983). New derivatives of methylxanthines: Effects of thiocaffeine, thiotheophylline and 8-phenyltheophylline on lipolysis and on phosphodieterase activities. Pharmacol. Res. Commun., 15, 131-143.
17. Fredholm, B. B. and Lindgren, E. (1984). The effects of alkylxanthines and other phosphodiesterase inhibitors on adenosine-receptor mediated decrease in lipolysis and cyclic AMP accumulations in rat rat cells. Acta Pharmacol. Toxicol., 54, 64-71.
18. Fredholm, B. B. (1980). Theophylline actions on adenosine receptors. Eur. J. Resp. Dis., 61, 29-36.
19. Al-Jafari, A. A., Junaid, M. A. and Alhomida, A. S. (1966). Investigation of the influence of theophylline feeding on total, free, short-chain acyl and long-chain acyl carnitine levels in skeletal muscle and liver of rats. In vivo, 10, 569-574.
20. Alhomida, A. S. (1997). Study of the effects of theophylline-related changes in total, free, short-chain acyl and long-chain acyl carnitine concentrations in rat heart. Toxicol., 121, 205-213.
21. Alhomida, A. S. (1996). Total, free, short-chain, long-chain acyl carnitine levels in Arabian camel milk (Camelus dromedarius). Ann. Nurt. Metabol., 40, 221-226.
22. Lilienthal, J. L., Zierler, K. L., Folk, B P., Buka, R. and Riley, M. J. (1950). A reference base and system for analysis of muscle constituents. J. Biol. Chem., 182, 501-508.
23. Markwell, M. A. K., Haes, S. M., Tolbert, N. E. and Bieber, L. L. (1981). Protein determination in membrane and lipoprotein samples: manual and automated procedures. Methods Enzymol., 72, 269-303.
24. Al-Kholafi, A. M. and Alhomida, A. S. (1977). Evaluation of theophylline-induced changes on plasma total, free, short-chain acyl and long-chain acyl carnitine concentrations in rats. Med. Sci. Res., 25, 31-34.
25. Winer, B. J., Brown, D. R., Michels, K., M (1991). Statistical Principles in Experimental Design. McGraw-Hill: New York.
26. Scammell, J. G. and Fregly, M. J. (1982). Effect of theophylline on thyroid status in the rat. Pharmacol., 25, 160-169.
27. Bukowiecki, L J., Lupien, J., Follea, N. and Jahjah, L. (1983). Effects of sucrose, caffeine and cola beverages on obesity, cold resistance and adipose tissue cellularity. Am. J. Physiol., 1244, R500-R507.
28. Donowitz, M., Tai, Y.-H. and Asarkof, N. (1980). Effects of serotonin on active electrolyte transport in rabbit ileum, gall bladder and colon. Am. J. Physiol., 239, G463-G472.
29. Field, M. (1971). Intestinal secretion: effect of cyclic AMP and its role in cholera. N. Engl. J. Med., 284, 1137-1142.
30. Mitenko, P, and Ogilvie, R (1973). Rational intravenous doses of theophylline. N. Engl. J. Med., 289, 600-603.
31. Rowe, D. J. F., Watson, I. D., Williams, J. and Berry, D. J. (1988). The clinical use and measurement of theophylline. Ann. Clin. Biochem., 25, 4-26.
32. Gross, C. J. and Henderson, L. M. (1984). Uptake of L-carnitine, D-carnitine and acetyl-L-carnitine by isolated guinea-pig enterocytes. Biochem. Biophys. Acta, 772, 209-212.
33. Hokland, B. M. and Bremer, J. (1986). Metabolism and excretion of carnitine and acylcarnitine in the perfused rat kidney. Biochem. Biophys. Acta, 886, 223-241.
34. Spindel, E. (1984). Action of the methylxanthines on the pituitary and pituitary-dependent hormones. In: The Methylxanthine Beverages and Foods: Chemistry, Consumption, and Health Effects. Alan R. Liss, Inc: New York, pp. 331-355.
35. Brass, E. P. (1992). Carnitine transport. In: L-Carnitine and its Role in Medicine: from Functions to Therapy. (Ferrari, R., DiMauro, S. and Sherwood, G., eds.) Academic Press: California, pp. 21-36.
36. Rebouche, C. J. (1989). Carnitine transport and tissue carnitine accretion in rats. Biochim. Biophys. Acta, 1033, 111-113.
37. Sartorelli, L., Mantovani, G and Ciman, M. (1989). Carnitine and deoxycarnitine concentration in rat tissues and urine after their administration. Biochim. Biophys. Acta, 1006, 15-18.
38. Alhomida, a. S., Duhaiman, A. S., Al-Jafari, A. A. and Junaid, M. A. (1996). Purification of carnitine acetyltransferase from the skeletal muscle of the camel (Camelus dromedarius). Mol. Cell, Biochem., 165, 95-101.
39. Alhomida, A. S., Al-Jafari, A. A., Duhaiman, A. S., Rabbani, N. and Junaid, M. A. (1996). Kinetic properties of purified carnitine acetyltransferase from the skeletal muscle of the Arabian camel (Camelus dromedarius). Biochimie, 78, 204-208.
40. Alhomida, A. S. (1996). Inhibition studies of the carnitine acetyltransferase from the skeletal muscle of the camel (Camelus dromedarius) by sulfhydride reagents and metal ions. Biochem. Mol. Biol. Int., 39, 923-931.
41. Alhomida, A. S. (1997). Investigation of the effects of theophylline administration on carnitine acetyltransferase activity of rat heart. J. Enz. Inhib , 12, 291-301.