Pancreatic enzyme-induced pancreatitis and systemic complications in rats

Japanese Journal of Pharmacology

Volumn 77, Issue 3, 1998, Pages 185-191

  Yamano, Mayumi ^a   Miyata, Keiji ^a   Yamada, Toshimitsu ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Acute pancreatitis; Elastase; Pancreatic enzyme; Pulmonary dysfunction; Trypsin

Indexed keywords

BILE SALT; CHYMOTRYPSIN A; KALLIKREIN; LEUKOCYTE ELASTASE; PANCREAS ENZYME; PANCREATIC ELASTASE; TAUROCHOLIC ACID; TRIACYLGLYCEROL LIPASE; TRYPSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; EDEMA; LIVER DISEASE; LUNG BLOOD VESSEL; LUNG DISEASE; MALE; NONHUMAN; PANCREAS; PANCREAS HEMORRHAGE; PANCREATITIS; RAT; WATER CONTENT;

EID: 0031713470     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.77.185     Document Type: Article

References (27)

1. Montravers P, Chollet-Martin S, Marmuse JP, Gougerot-Pocidalo MA and Desmonts JM: Lymphatic release of cytokines during acute lung injury complicating severe pancreatitis. Am J Respir Crit Care Med 152, 1527-1533 (1995)
2. Tahamont MV, Barie PS, Blumenstock FA, Hussain MH and Malik AB: Increased lung vascular permeability after pancreatitis and trypsin infusion. Am J Pathol 109, 15-26 (1982)
3. 2CaEDTA in experimental hemorrhagic pancreatitis in pigs. Scand J Gastroenterol 22, 35-41 (1987)
4. Kiviniemi H, Stahlberg MI, Jalovaara P, Ramo J and Kairaluoma M: Methylprednisolone in acute canine hemorrhagic pancreatitis. Acta Chir Scand 154, 31-35 (1988)
5. Chardavoyne R, Asher A, Bank S, Stein TA and Wise L: Role of reactive oxygen metabolites in early cardiopulmonary changes of acute hemorrhagic pancreatitis. Dig Dis Sci 34, 1581-1584 (1989)
6. Zhu ZH, Holt S, el Lbishi MS, Grady T, Taylor TV and Powers RE: A somatostatin analogue is protective against retrograde bile salt-induced pancreatitis in the rat. Pancreas 6, 609-613 (1991)
7. Klar E, Schratt W, Foitzik T, Buhr H, Herfarth C and Messmer K: Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas. Dig Dis Sci 39, 2639-2644 (1994)
8. Nakae Y, Naruse S, Kitagawa M, Hirao S, Yamamoto R and Hayakawa T: Activation of trypsinogen in experimental models of acute pancreatitis in rats. Pancreas 10, 306-313 (1995)
9. Stone PJ, Morris SM, Martin BM, McMahon MP, Faris B and Franzblau C: Repair of protease-damaged elastin in neonatal rat aortic smooth muscle cell cultures. J Clin Invest 82, 1644-1654 (1988)
10. Morris SM and Stone PJ: Immunocytochemical study of the degradation of elastic fibers in a living extracellular matrix. J Histochem Cytochem 43, 1145-1153 (1995)
11. Lungarella G, Gardi C, de Santi MM and Luzi P: Pulmonary vascular injury in pancreatitis: evidence for a major role played by pancreatic elastase. Exp Mol Pathol 42, 44-59 (1985)
12. Toki N, Sumi H and Takasugi S: Purification and characterization of kallikrein from plasma of patients with acute pancreatitis. Clin Sci 60, 199-205 (1981)
13. Fujimoto K, Ogawa M, Murata A, Kitahara T, Takatsuka Y and Kosaki G: Diagnostic significance of immunological assay of pancreatic elastases in acute pancreatitis. Clin Biochem 16, 26-27 (1983)
14. Iwaki K, Ogawa M, Tanaka S and Kosaki G: Radioimmunoassay for human pancreatic chymotrypsin and measurement of serum immunoreactive chymotrypsin contents in various diseases. Res Commun Chem Pathol Pharmacol 40, 489-496 (1983)
15. Lesi C, Ruffilli E, De-Mutiis R, Zoni L, Baldoni F and Malaguti P: Serum elastase 1 in clinical practice. Pancreas 3, 444-449 (1988)
16. Vaziri ND, Chang D, Malekpour A and Radaht S: Pancreatic enzymes in patients with end-stage renal disease maintained on hemodialysis. Am J Gastroenterol 83, 410-412 (1988)
17. Le Moine O, Devaster JM, Deviere J, Thiry P, Cremer M and Ooms HA: Trypsin activity. A new marker of acute alcoholic pancreatitis. Dig Dis Sci 39, 2634-2638 (1994)
18. Niederau C, Fronhoffs K, Klonowski H and Schulz HU: Active pancreatic digestive enzymes show striking differences in their potential to damage isolated rat pancreatic acinar cells. J Lab Clin Med 125, 265-275 (1995)
19. Hong SS, Case RM and Kim KH: Analysis in the isolated perfused cat pancreas of factors implicated in the pathogenesis of pancreatitis. Pancreas 3, 450-458 (1988)
20. Balldin G, Borgstrom A, Genell S and Ohlsson K: The effect of peritoneal lavage and aprotinin in the treatment of severe acute pancreatitis. Res Exp Med Berl 183, 203-213 (1983)
21. Bergenfeldt M, Berling R and Ohlsson K: Levels of leukocyte proteases in plasma and peritoneal exudate in severe, acute pancreatitis. Scand J Gastroenterol 29, 371-375 (1994)
22. Ventrucci M, Pezzilli R, Gullo L, Plate L, Sprovieri G and Barbara L: Role of serum pancreatic enzyme assays in diagnosis of pancreatic disease. Dig Dis Sci 34, 39-45 (1989)
23. Malfertheiner P and Kemmer TP: Clinical picture and diagnosis of acute pancreatitis. Hepatogastroenterology 38, 97-100 (1991)
24. Reichart E, Boerkmann P, Plenat F, Marie B, Rogerieux F and Lambre C: The trypsin-induced leucostasis which leads to emphysema in the hamster is not due to contaminating endotoxins. J Pathol 178, 215-220 (1996)
25. Garcia-Szabo RR, Johnson A and Malik AB: Leukocytes are required for the trypsin-induced increase in lung vascular permeability. Am J Pathol 124, 377-383 (1986)
26. Ip MP, KIeinerman J and Sorensen J: The effect of elastase on pulmonary elastin and collagen: comparison of intravenous and intratracheal exposure. Exp Lung Res 1, 181-189 (1980)
27. Stokke T, Burchardi H, Hensel I, Kostering H, Kathner T and Rahlf G: Continuous intravenous infusion of elastase in normal and agranulocytic minipigs - effects on the lungs and the blood coagulation system. Resuscitation 14, 61-79 (1986)