Plasma homocysteine, vitamin B6, vitamin B12 and folic acid in end-stage renal disease during low-dose supplementation with folic acid

American Journal of Nephrology

Volumn 18, Issue 5, 1998, Pages 367-372

  Hong, Sae Yong ^a,b   Yang, Dong Ho ^a   Chang, Sung Keun ^a  

^a Soonchunhyang University   (South Korea)

^b SoonChunHyang Univerity   (South Korea)

Author keywords

End stage renal disease; Folic acid; Hemodialysis; Homocysteine; Vitamin B12; Vitamin B6

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PYRIDOXINE;

ADULT; ARTICLE; BLOOD LEVEL; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; HEMODIALYSIS; HUMAN; HYPERHOMOCYSTEINEMIA; MALE; PRIORITY JOURNAL;

ADULT; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; HYPERTENSION; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PYRIDOXINE; RENAL DIALYSIS; VITAMIN B 12;

EID: 0031713016     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000013378     Document Type: Article

References (23)

1. Parfrey PS: Cardiac and cerebrovascular disease in chronic uremia. Am J Kid Dis 1993;21: 77-80.
2. Chauveau P, Chadefaux B, Coudé M, Aupetit J, Hannedouche T, Kamoun P, Jungers P: Hyperhomocysteinemia, a risk factor for atherosclerosis in chronic uremic patients. Kidney Int 1993;43(suppl 41):S72-77.
3. Bachmann J, Tepel M, Raidt H, Riezler R, Graefe U, Langer K, Zidek W: Hyperhomocysteinemia and the risk for vascular disease in hemodialysis patients. J Am Soc Nephrol 1995; 6:121-125.
4. Tsai C, Perrella MA, Yoshizumi M, Hsien CM, Habe E. Schlagel R, Lee ME: Promotion of vascular smooth muscle cell growth by homocysteine: A link to atherosclerosis. Proc Natl Acad Sci USA 1994;91:6369-6373.
5. Harpel PC, Chang VT, Bort W: Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: A potential biochemical link between thrombosis, atherosclerosis, and sulfhydryl compound metabolism. Proc Natl Acad Sci USA 1992;89:10193-10197.
6. Hajjar KA: Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J Clin Invest 1993;91:2873-2879.
7. Perna AF, Ingrosso D, Galletti P, Zappia V, De Santo NG: Membrane protein damage and methylation reaction in chronic renal failure. Kidney Int 1996;50:358-366.
8. Dennis VW, Robinson K: Homocysteinemia and vascular disease in end-stage renal disease. Kidney Int 1996;57.S11-S17.
9. Wilcken DEL, Gupta VJ: Sulphur containing amino acids in chronic renal failure with particular reference to homocysteine and cysteinehomocysteine mixed disulphide. Eur J Clin Invest 1979;9:301-317.
10. Wilcken DEL, Dudman NPB, Tyrrell PA, Robertson MR: Folic acid lowers elevated plasma homocysteine in chronic renal insufficiency: Possible implications for prevention of vascular disease. Metabolism 1988;37:697-701.
11. Ellis JM, McCully KS: Prevention of myocardial infarction by vitamin B6. Res Commun Mol Pathol Pharmacol 1995;89:208-220.
12. 12, and folate. Am J Epidemiol 1996;143:845-859.
13. Mayer EL, Jacobsen DW, Robinson K: Homocysteine and coronary atherosclerosis. J Am Coll Cardiol 1996;27:517-527.
14. Robinson K, Mayer EL, Miller DP, Green R, van Lente F, Gupta A, Kottke-Marchant K, Savon SR, Selhub J, Nissen SE, Kutner M, Topol EJ, Jacobsen DW: Hyperhomocysteinemia and low pyridoxal phosphate: Common and independent reversible risk factors for coronary artery disease. Circulation 1995;92: 2825-2830.
15. Arnadottir M, Brattstrom L, Simonsen O, Thysell H, Hultberg B, Andersson A, Nilsson-Ehle P: The effect of high-dose pyridoxine and folic acid supplementation on serum lipid and plasma homocysteine concentrations in dialysis patients. Clin Nephrol 1993;40:236-240.
16. Bostom AG, Shemin D, Lapane KL, Hume AL, Yobum D, Nadeau M, Bendich A, Selhub J, Rosenberg IH: High-dose B-bitamin treatment of hyperhomocysteinemia in dialysis patients. Kidney Int 1996;49:147-152.
17. Lazarus JM, Denker BM, Owen WF: Hcmodialysis, chap 56; in Brenner BM (ed): The Kidney, ed 5. Philadelphia, Saunders, 1996, p 2454.
18. Descombes E, Hanck AB, Fellay G: Water soluble vitamins in chronic hemodialysis patients and need for supplementation. Kidney Int 1993;43:1319-1325.
19. Atkins GL, Nimmo IA: Current trends in the estimation of Michaelis-Menten parameters. Anal Biochem 1980;104:1-9.
20. Araki A, Sako Y, Fukishima Y, Matsumoto M, Asada T, Kita T: Plasma sulfhydryl-containing amino acids in patients with cerebral infarction and in hypertensive subjects. Atherosclerosis 1989;79:139-146.
21. Refsum H, Heiland S, Ueland PM: Radioenzymic determination of homocysteine in plasma and urine. Clin Chem 1985;31:624-628.
22. Chadefaux B, Coude M, Hamet M, Aupetit J, Kamoun P: Rapid determination of total homocysteine in plasma. Clin Chem 1989;35: 2002-2013.
23. Guyton C, Hall JE: Dietary balances, regulation of feeding, obesity and starvation, vitamins and minerals, chap 71; in Guyton C, Hall JE (eds): Textbook of Medical Physiology, ed 9. Philadelphia, Saunders, 1996, pp 889-902.