Intramuscular tramadol versus ketorolac in the treatment of pain following nasal surgery: A controlled multicenter trial

Current Therapeutic Research - Clinical and Experimental

Volumn 59, Issue 9, 1998, Pages 608-618

  Colletti, Vittorio ^a   Carner, Marco ^a   Vincenzi, Andrea ^b   Dallari, Stefano ^b   Mira, Eugenio ^c   Benazzo, Marco ^c   Cosentino, Gaetano ^d   Bellussi, Luisa ^d   Passali, Desiderio ^d  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d UNIVERSITY OF SIENA   (Italy)

Author keywords

Ketorolac; Nasal surgery; Postoperative pain; Tramadol

Indexed keywords

KETOROLAC; TRAMADOL;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG TOLERANCE; FEMALE; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NOSE SURGERY; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLEEP; TREATMENT INDICATION;

EID: 0031712296     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(98)85059-5     Document Type: Article

References (27)

1. Davies P, Ogg T. Postoperative pain relief. Practitioner. 1992;236:840-842.
2. Linscott MS. Analgesics in the management of acute pain. Clin Ther. 1986;1:9-21.
3. Szabo S, Spill WF, Rainsford KD. Non-steroidal anti-inflammatory drug-induced gastropathy. Mechanisms and management. Med Toxicol Adverse Drug Exp. 1989;4:77-94.
4. Benedetti C. Acute pain: Physiopathology and consequences. ALGOS. 1991;8:34-44.
5. Duthie DJR, Nimmo WS. Adverse effects of opioid analgesic drugs. Br J Anaesth. 1987; 59:61-77.
6. Raffa RB, Friderichs E. The basic science aspect of tramadol hydrochloride. Pain Rev. 1996;3:249-271.
7. Raffa RB, Friderichs E, Reimann W, et al. Opioid and non opioid components independently contribute to the mechanism of action of tramadol, an ́atypicaĺ opioid analgesic. J Pharmacol Exp Ther. 1992;260:275-285.
8. Driessen B, Schultz H, Reimann W. Evidence for a non opioid component in the analgesic action of tramadol. Naunyn-Schmiedeberg's Arch Pharmacol. 1990;341:R104. Abstract 415.
9. Driessen B, Reimann W. Interaction of the central analgesic, tramadol, with the uptake and release of 5-hydroxytryptamine in the rat brain in vitro. Br J Pharmacol. 1992;105: 147-151.
10. Desmeules JA, Piguet V, Collart L, Dayer P. Contribution of monoaminergic modulation to the analgesic effect of tramadol. Br J Clin Pharmacol. 1996;41:7-12.
11. Tarradell R, Pol O, Farré M, et al. Respiratory and analgesic effects of meperidine and tramadol in patients undergoing orthopedic surgery. Methods Find Exp Clin Pharmacol. 1996;18:211-218.
12. Vickers MD, O'Flaherty D, Szekely SH, et al. Tramadol: Pain relief by an opioid without depression of respiration. Anaesthesia. 1992;47:291-296.
13. Cossmann M, Kohnen C. General tolerability and adverse event profile of tramadol hydrochloride. Rev Contemp Pharmacother. 1995;6:513-531.
14. Richter W, Barth H, Flohe L, Giertz H. Clinical investigation on the development of dependence during oral therapy with tramadol. Arzneim-Forsch Drug Res. 1985;35:1742-1744.
15. Vickers MD. The efficacy of tramadol hydrochloride in the treatment of postoperative pain. Rev Contemp Pharmacother. 1995;6:499-506.
16. Canepa G, Di Somma C, Ghia M, et al. Post-operative analgesia with tramadol: A controlled study compared with an analgesic combination. Int J Clin Pharmacol Res. 1993;XIII:43-51.
17. Fassolt A. Suppression of post-operative wound pain with Tramai (tramadol) 100 mg im. Schweiz Rundsch Med Prax. 1981;70:435-440.
18. Duggan AK. The cost of managing post-operative pain, a comparison of tramadol and morphine. Br J Med Econ. 1995;9:59-66.
19. Rooks WH, Maloney PJ, Shott LD, et al. The analgesic and anti-inflammatory profile of ketorolac and its tromethamine salt. Drugs Exp Clin Res. 1985;XI:479-492.
20. Kupers R, Callebaut V, Debois V, et al. Efficacy and safety of oral tramadol and pentazocine for postoperative pain following prolapsed intervertebral disc repair. Acta Anaesthesiol Belg. 1995;46:31-37.
21. Lehmann KA. Tramadol for the management of acute pain. Drugs. 1994;47(Suppl 1):19-32.
22. Lanzetta A, Vizzardi M, Letizia G, et al. Intramuscular tramadol versus ketorolac in patients with orthopedic and traumatologic postoperative pain: A comparative multicenter trial. Curr Ther Res. 1998;59:39-47.
23. Del Favero A. Ketorolac: Le rapioni di uno preoccupazione. Informazioni sui formaci. 1993;17:81-84.
24. Choo V, Lewis S. Ketorolac doses reduced. Lancet. 1993;342:109.
25. CPMP recommends ketorolac changes. SCRIP. 1993;1832:17.
26. Strom BL, Berlin JA, Kinman JL, et al. Parenteral ketorolac and risk of gastrointestinal and operative site bleeding. A postmarketing surveillance study. JAMA. 1996;275:376-382.
27. Radbruch L, Grond S, Lehmann KA. A risk-benefit assessment of tramadol in the management of pain. Drug Saf. 1996;15:8-29.