Regioselective synthesis of new triheterocyclic compounds from 1,4- benzodiazepine

Synthetic Communications

Volumn 28, Issue 22, 1998, Pages 4221-4232

  Benelbaghdadi, R ^a   Hasnaoui, A ^a   Lavergne, J P ^b   Giorgi, M ^c   Pierrot, M ^c  

^a FACULTÉ DES SCIENCES SEMLALIA   (Morocco)

^b CNRS   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 OXADIAZOLO[4,5 D][1,4]BENZODIAZEPINE; 1,2,4 TRIAZOLO[4,3 D][1,4]BENZODIAZEPINE; BENZODIAZEPINE DERIVATIVE; HETEROCYCLIC COMPOUND; NITRILE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CYCLIZATION; EXTRACTION; STEREOISOMERISM; SYNTHESIS;

EID: 0031712172     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919809458703     Document Type: Article

References (12)

1. Hasnaoui, A., El Messaoudi, M., Lavergne, J.-P., Recl. Trav. Chim. Pays-Bas, 1985, 104, 129.
2. El Messaoudi, M., Hasnaoui, A., El Mouhtadi, M., Goupil, J.-M., Lavergne, J.-P., J. Heterocyclic Chem., 1988, 25, 453.
3. El Messaoudi, M., Hasnaoui, A., El Mouhtadi, M., Lavergne, J.-P., Bull. Soc. Chim. Belg., 1992, 101, 977.
4. Hasnaoui, A., Baouid, A., Lavergne, J.-P. J. Heterocyclic Chem., 1991, 28, 453.
5. Baouid, A., Benharref, A., Hasnaoui, A., Lavergne, J.-P. Bull. Soc. Chim. Belg., 1994, 103, 743.
6. El Messaoudi, M., Hasnaoui, A., Lavergne, J.-P., Synth. Commun., 1994, 24, 513.
7. Baouid, A., Hasnaoui, A., Lavergne, J.-P., Bull. Soc. Chim. Belg., 1996, 105, 339.
8. Benelbaghdadi, R., Hasnaoui, A., Lavergne, J.-P., Ibid, 1997, 106, 813.
9. Bellantuono, C., Reggi, G., Tognoni, G., Garattini, S., Drugs, 1980, 19, 195.
10. Bartsch, H., Erker, T., J. Heterocyclic Chem., 1988, 25, 1151.
11. 1/n. Cell length a: 16.21(5), cell length b: 9.24(5), cell length c: 16.60(5), cell angle alpha: 90.00 (2), cell angle beta: 94.42(2), cell angle gamma: 90.00(2), cell volume: 2468(1), cell formula units z: 4. Diffraction radiation type : Mo-K\α, radiation wavelength: 0.71073 A°. Cell measurement temperature: 298°K. Data collection: diffraction measurement device: Enraf Nonius CAD-4. Experimental absorption correction type: none. Diffraction reflections number: 6730, reflections number total: 4145, reflections number observed: 2165. Refinement data: refine ls structure factor coefficient: F. Refine ls R factor observed: 0.061, refine ls wR factor observed: 0.052, refine ls number reflections: 2165, refine ls number parameters: 316. Atom type scattering source: International Tables for Xray Crystallography (1974, vol.4).
12. 1/n. Cell length a: 8.238(2), cell length b: 13.581(3), cell length c: 18.540(3), cell angle alpha: 90.00(1), cell angle beta: 94.42(1), cell angle gamma: 90.00(1), cell volume: 2068(1), cell formula units z: 4. Diffraction radiation type: Mo-K\α, radiation wavelength: 0.71073 A°. Cell measurement temperature: 294°K. Data collection: diffraction measurement device: Enraf Nonius CAD-4. Experimental absorption correction type: none. Diffractionn reflections number: 7513, reflections number total: 3632, reflections number observed: 2562. Refinement data: refine ls structure factor coefficient: F. Refine ls R factor observed: 0.058, refine ls wR factor observed: 0.045, refine ls number reflections: 2562, refine ls number parameters: 290. Atom type scattering source: International Tables for Xray Crystallography (1974, vol.4).