Chlorambucil-induced pulmonary disease: A case report and review of the literature

Annals of Hematology

Volumn 77, Issue 1-2, 1998, Pages 85-87

  Khong, H T ^a   McCarthy, J ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Chlorambucil; Chronic lymphocytic leukemia; Interstitial pneumonitis; Pulmonary fibrosis

Indexed keywords

ANTIBIOTIC AGENT; CHLORAMBUCIL; PREDNISONE; STEROID;

AGED; ARTICLE; CASE REPORT; CHRONIC LYMPHATIC LEUKEMIA; DRUG ACCUMULATION; HUMAN; HUMAN CELL; INTERSTITIAL PNEUMONIA; MALE; PRIORITY JOURNAL;

AGED; ANTINEOPLASTIC AGENTS, ALKYLATING; CHLORAMBUCIL; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC; LUNG DISEASES; MALE;

EID: 0031712119     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002770050418     Document Type: Article

References (25)

1. Rubio FA (1972) Possible pulmonary effects of alkylating agents. N Engl J Med 287:1150-1151
2. Jacobs S (1975) The Hamman-Rich syndrome following treatment for lymphoma with chlorambucil. J La State Med Soc 127:311-315
3. Rose MS (1975) Busulfan toxicity syndrome caused by chlorambucil. Br Med J 1:123
4. Crofton J, Douglas A (eds) (1976) Respiratory diseases, 2nd edn. Blackwell Scientific Publications. Oxford
5. Refvem O (1977) Fatal intraalveolar and interstitial lung fibrosis in chlorambucil-treated chronic lymphocytic leukemia. Mt Sinai J Med (NY) 44:847-851
6. Cole SR, Myers TJ, Klalsky AU (1978) Pulmonary disease with chlorambucil therapy. Cancer 41:455-459
7. Godard PH, Marty JP, Michel FB (1979) Interstitial pneumonia and chlorambucil. Chest 76:471-473
8. Lane SD, Besa EC, Justh G, Joseph RR (1979) Fatal interstitial lung disease following high-dose chlorambucil therapy. Proc Am Soc Clin Oncol 20:313
9. Grand M, Spector JI, Zimbler H, Ross JS (1983) Pulse-dose chlorambucil-induced interstitial pneumonitis. Proc Am Soc Clin Oncol 2:C85
10. Hagemann SG (1984) Alveolitis and lung fibrosis with chlorambucil therapy. Prax Klin Pneumol 38:108-111
11. Carr ME (1986) Chlorambucil-induced pulmonary fibrosis: report of a case and review. Va Med 113:677-680
12. Giles FJ, Smith MP, Goldstone AH (1990) Chlorambucil lung toxicity. Acta Haematol 83:156-158
13. Mohr M, Kingreen D, Ruhl H, Huhn D (1993) Interstitial lung disease - an underdiagnosed side effect of chlorambucil? Ann Hematol 67:305-307
14. Crestani B, Jaccard A, Israel Biet D, Coudere LJ, Frija J, Clauvel JP (1994) Chlorambucil-associated pneumonitis. Chest 105:634-636
15. Green RA, Nichols NJ (1959) Pulmonary involvement in leukemia. Am Rev Respir Dis 80:833-844
16. Foon KA, Rai KR, Gale RP (1990) Chronic lymphocytic leukemia: new insights into biology and therapy. Ann Intern Med 113:525-539
17. Bodey GP (1975) Infections in cancer patients. Cancer Treat Rev 2:89-128
18. Robertson TI (1990) Complications and causes of death in B cell chronic lymphocytic leukaemia: a long term study of 105 patients. Aust N Z J Med 20:44-50
19. Sanders C, Perez EA, Lawrence HJ (1992) Opportunistic infections in patients with chronic lymphocytic leukemia following treatment with fludarabine. Am J Hematol 39:314-315
20. Travis LB, Curtis RE, Hankey BF, Fraumeni JF (1992) Second cancers in patients with chronic lymphocytic leukemia. J Natl Cancer Inst 84:1422-1427
21. Bertodero G, Scrihano G, Podda L, Berti R, Amadori G (1994) Occurrence of second neoplasms in chronic lymphocytic leukemia - experience at Padua hospital between 1979 and 1991. Ann Hematol 69:195-198
22. Rosenow EC (1972) The spectrum of drug-induced pulmonary disease. Ann Intern Med 77:977-991
23. Kreisman H, Wolkove N (1992) Pulmonary toxicity of anti-neoplastic therapy. Semin Oncol 19:508-520
24. Littler WA, Kay JM, Hasleton PS, Heath D (1969) Busulfan lung. Thorax 24:639-655
25. Patel AR, Shaw PC, Rhee HL, Sassoon H, Rao KP (1976) Cyclophosphamide therapy and interstitial pulmonary fibrosis. Cancer 38:1542-1549