Inhibitory effects of S-nitrosocaptopril on vasomotor tone

Acta Pharmacologica Sinica

Volumn 19, Issue 5, 1998, Pages 485-488

  Lin, Mo Jun ^a   Yang, Xin Ping ^a   Wang, Jing ^a   Jia, Bing Jun ^a   Jia, Li ^b  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Angiotensin converting enzyme inhibitor; Arginine; Captopril; Nitric oxide; Phenylephrine; Renal circulation; S nitrosocaptopril; Thoracic aorta; Vascular endoth'elium; Vasodilation

Indexed keywords

ARGININE; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; N(G) METHYLARGININE; NITRIC OXIDE; S NITROSOCAPTOPRIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; DRUG EFFECT; MALE; NONHUMAN; PERFUSION PRESSURE; RABBIT; RENAL ARTERY; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASODILATATION;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; AORTA, THORACIC; ARGININE; CAPTOPRIL; ENDOTHELIUM, VASCULAR; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PHENYLEPHRINE; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RENAL CIRCULATION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 0031711184     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Furchgott RF. Role of endothelium in responses of vascular smooth muscle. Circ Res 1983; 53: 557-73.
2. Singh RT, Hogg N, Joseph J, Kalyanaraman B. Mechanism of nitric oxide release from S-nitrosothiols. J Biol Chem 1996; 271: 18596-603.
3. Stamler JS, Jaraki O, Osborne J, Simon DI, Keaney J, Vita J, et al. Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc Natl Acad Sci USA 1992; 89: 7674-7.
4. Jia L. Some advance in angiotensin converting enzyme inhibitor. Prog Physiol Sci 1985; 16: 229-34.
5. Jia L, Liu XJ, Pei RJ. The clinical trial and medical application prospect of nitric oxide and its donor. Chin Pharmacol Bull 1997; 13: 204-6.
6. Loscalzo J, Smick D, Andon N, Cooke J. S-nitrosocaptopril. I . Molecular characterization and effects on the vasculature and on platelets. J Pharmacol Exp Ther 1989; 249: 726-9.
7. Jia L, Furchgott RF. Inhibition by sulfhydryl compounds of vascular relaxation induced by nitric oxide and endothelium-derived relaxing factor. J Pharmacol Exp Ther 1993; 267: 371-8.
8. Wang J, Jia BJ. Effects of pressor area of ventral surface of medulla oblongata on the vasotonicity of renal vessels of rats. Acta Physiol Sin 1993; 45: 359-67.
9. Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333: 664-6.
10. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109-42.
11. Fung H-L, Chong S, Kowaluk E, Hough K, Kakemi M. Mechanisms for the pharmacologic interaction of organic nitrates with thiols. Existence of an extracellular pathway for the reversal of nitrate vascular tolerance by N-acetylcysteine. J Pharmacol Exp Ther 1988; 245: 524-30.
12. Taddei S, Virdis A, Mattei P, Ghiadoni L, Sudano I, Salvetti A. Defective L-arginine-nitric oxide pathway in offspring of essential hypertensive patients. Circulation 1996; 94: 1298-1303.