Effect of time-varying load on degree of bronchoconstriction in the dog

Journal of Applied Physiology

Volumn 85, Issue 4, 1998, Pages 1464-1470

  Shinozuka, Norihiro ^a   Lavoie, Jean Pierre ^c   Martin, James G ^a   Bates, Jason H T ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Airway smooth muscle contraction; Impedance; Latch bridge; Lung resistance and elastance

Indexed keywords

METHACHOLINE;

ANIMAL EXPERIMENT; ARTICLE; BREATHING MUSCLE; BRONCHOSPASM; DOG; LUNG MECHANICS; LUNG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION;

EID: 0031709693     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.85.4.1464     Document Type: Article

References (22)

1. Antol, P., M. Fujita, and R. E. Hyatt. Characteristics of tachyphylaxis to inhaled histamine in anesthetized dogs. J. Appl. Physiol. 65: 1938-1943, 1988.
2. Balassy, Z., M. Mishima, and J. H. T. Bates. Changes in regional lung impedance after intravenous histamine bolus in dogs: effects of lung volume. J. Appl. Physiol. 78: 875-880, 1995.
3. Bates, J. H. T., A.-M. Lauzon, G. S. Dechman, G. N. Maksym, and T. F. Schuessler. Temporal dynamics of pulmonary response to intravenous histamine in dogs: effects of dose and lung volume. J. Appl. Physiol. 76: 616-626, 1994.
4. Bates, J. H. T., and R. Peslin. Acute pulmonary response to intravenous histamine at fixed lung volume in dogs. J. Appl. Physiol. 75: 405-411, 1993.
5. Bates, J. H. T., T. F. Schuessler, C. Dolman, and D. H. Eidelman. Temporal dynamics of acute isovolume bronchoconstriction in the rat. J. Appl. Physiol. 82: 55-62, 1997.
6. Coon, R. L. Reflex bronchodilation produced by phasic ventilation of the lungs. J. Appl. Physiol. 74: 811-816, 1993.
7. Dillon, P. F., M. O. Aksoy, S. P. Driska, and R. A. Murphy. Myosin phosphorylation and the crossbridge cycle in arterial smooth muscle. Science 211: 495-497, 1981.
8. Ding, D. J., J. G. Martin, and P. T. Macklem. Effects of lung volume on maximal methacholine-induced bronchoconstriction in normal humans. J. Appl. Physiol. 62: 1324-1330, 1987.
9. Fish, J. E., M. G. Ankin, J. F. Kelly, and V. I. Peterman. Regulation of bronchomotor tone by lung inflation in asthmatic and nonasthmatic subjects. J. Appl. Physiol. 50: 1079-1086, 1981.
10. Gerthoffer, W. T., and R. A. Murphy. Myosin phosphorylation and regulation of cross-bridge cycle in tracheal smooth muscle. Am. J. Physiol. 244 (Cell Physiol. 13): C182-C187, 1983.
11. Gunst, S. J., M.-F. Wu, and D. D. Smith. Contraction history modulates isotonic shortening velocity in smooth muscle. Am. J. Physiol. 265 (Cell Physiol. 34): C467-C476, 1993.
12. Li, W., and N. L. Stephens. Auxotonic loading and airway smooth muscle shortening. Can. J. Physiol. Pharmacol. 72: 1458-1463, 1994.
13. Lutchen, K. R., Z. Hantos, F. Petak, A. Adamicza, and B. Suki. Airway inhomogeneities contribute to apparent lung tissue mechanics during constriction. J. Appl. Physiol. 80: 1841-1849, 1996.
14. 1 measurements in a methacholine provocation test. Eur. Respir. J. 6: 680-686, 1993.
15. Moreno, R. H., C. Lisboa, J. C. Hogg, and P. D. Paré. Limitation of airway smooth muscle shortening by cartilage stiffness and lung elastic recoil in rabbits. J. Appl. Physiol. 75: 738-744, 1993.
16. Nagase, T., J. G. Martin, and M. S. Ludwig. Comparative study of mechanical interdependence: effect of lung volume on Raw during induced constriction. J. Appl. Physiol. 75: 2500-2505, 1993.
17. Robatto, F. M., S. Simard, H. Orana, P. T. Macklem, and M. S. Ludwig. Effect of lung volume on plateau response of airways and tissue to methacholine in dogs. J. Appl. Physiol. 73: 1908-1913, 1992.
18. Sasaki, H., and F. G. Hoppin, Jr. Hysteresis of contracted airway smooth muscle. J. Appl. Physiol. 47: 1251-1262, 1979.
19. Shen, X., S. Gunst, and R. S. Tepper. The effect of tidal ventilation on airway responsiveness to methacholine in rabbits (Abstract). Am. J. Respir. Crit. Care Med. 155: A544, 1997.
20. Shore, S., and J. G. Martin. Tachyphylaxis to inhaled aerosolized histamine in anesthetized dogs. J. Appl. Physiol. 59: 1355-1363, 1985.
21. Skloot, G., S. Permutt, and A. Togias. Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration. J. Clin. Invest. 96: 2393-2403, 1995.
22. Stephens, N. L., G. Morgan, W. Kepron, and C. Y. Seow. Changes in cross-bridge properties of sensitized airway smooth muscle. J. Appl. Physiol. 61: 1492-1498, 1986.