Urease plays an important role in the chemotactic motility of Helicobacter pylori in a viscous environment

Infection and Immunity

Volumn 66, Issue 10, 1998, Pages 4832-4837

  Nakamura, Hiroki ^a   Yoshiyama, Hironori ^a   Takeuchi, Hiroaki ^a   Mizote, Tomoko ^a,b   Okita, Kiwamu ^a   Nakazawa, Teruko ^a  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b YAMAGUCHI PREFECTURAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; POVIDONE; UREASE;

ANIMAL CELL; ARTICLE; BACTERIAL COLONIZATION; CELL ADHESION; CELL MOTILITY; CHEMOTAXIS; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; GNOTOBIOTICS; HELICOBACTER PYLORI; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; STOMACH BIOPSY;

HELICOBACTER PYLORI;

EID: 0031707478     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.10.4832-4837.1998     Document Type: Article

References (30)

1. Adler, J. 1973. A method for measuring chemotaxis and use of the method to determine optimum conditions for chemotaxis by Escherichia coli. J. Gen. Microbiol. 74:77-91.
2. Atsumi, T., L. McCarter, and Y. Imae. 1992. Polar and lateral flagellar motors of marine Vibrio are driven by different ion-motive forces. Nature 355:182-184.
3. Berg, H. C. 1974. Dynamic properties of bacterial flagellar motors. Nature 249:77-79.
4. Blaser, M. J. 1993. Helicobacter pylori: microbiology of a 'slow' bacterial infection. Trends Microbiol. 1:255-260.
5. Clyne, M., and B. Drumim. 1996. The urease enzyme of Helicobacter pylori does not function as an adhesin. Infect. Immun. 64:2817-2820.
6. Creno, R. J., R. E. Wenk, and P. Bohlig. 1970. Automated micromeasurement of urea using urease and the Berthelot reaction. Am. J. Clin. Pathol. 54:828-832.
7. Eaton, K. A., D. R. Morgan, and S. Krakowka. 1992. Motility as a factor In the colonisation of gnotobiotic piglets by Helicobacter pylori. J. Med. Microbiol. 37:123-127.
8. Eaton, K. A., and S. Krakowka. 1994. Effect of gastric pH on urease-dependent colonization of gnotobiotic piglets by Helicobacter pylori. Infect. Immun. 62:3604-3607.
9. The EUROGAST Study Group. 1993. An international association between Helicobacter pylori infection and gastric cancer. Lancet 341:1359-1362.
10. Goodwin, C. S., J. A. Armstrong, T. Chilvers, M. Peters, M. D. Collins, L. Sly, W. McConnell, and W. E. S. Harper. 1989. Transfer of Campylobacter pylori and Campylobacter mustelae to Helicobacter gen. nov. as Helicobacter pylori comb. nov. and Helicobacter mustelae comb. nov., respectively. Int. J. Syst. Bacteriol. 39:397-405.
11. Hazel, S. L., A. Lee, L. Brady, and W. Hennessy. 1986. Campylobacter pyloridis and gastritis: association with intercellular spaces and adaptation to an environment of mucus as important factors In colonization of the gastric epithelium. J. Infect. Dis. 153:658-663.
12. Hu, L.-T., and H. L. T. Mobley. 1990. Purification and N-terminal analysis of urease from Helicobacter pylori. Infect. Immun. 58:992-998.
13. Jones, C. J., and S. Aizawa. 1991. The bacterial flagellum and flagellar motor: structure, assembly and function. Adv. Microb. Physiol. 32:109-172.
14. Khan, S., and R. M. Macnab. 1980. Proton chemical potential, proton electrical potential and bacterial motility. J. Mol. Biol. 138:599-614.
15. Kirschner, D. E., and M. J. Blaser. 1995. The dynamics of Helicobacter pylori infection of the human stomach. J. Theor. Biol. 176:281-290.
16. Macnab, R. M. 1992. Genetics and biogenesis of bacterial flagella. Annu. Rev. Genet. 26:131-158.
17. Manson, M. D., P. M. Tedesco, and H. C. Berg. 1980. Energetics of flagellar rotation In bacteria. J. Mol. Biol. 138:541-561.
18. Mendz, G. L., and S. L. Hazell. 1996. The urea cycle of Helicobacter pylori. Microbiology 142:2959-2967.
19. 3 into male rats and mice. Am. J. Anat. 106:247-265.
20. Mizote, T., H. Yoshiyama, and T. Nakazawa. 1997. Urease-independent chemotactic responses of Helicobacter pylori to urea, urease inhibitors, and sodium bicarbonate. Infect. Immun. 65:1519-1521.
21. Mobley, H. L. T., M. J. Cortesia, L. E. Rosenthal, and B. D. Jones. 1988. Characterization of urease from Campylobacter pylori. J. Clin. Microbiol. 26:831-836.
22. Parsonnet, J., S. Hansen, L. Rodriguez, A. B. Gelb, R. A. Warnke, E. Jellum, N. Orentreich, J. H. Vogelman, and G. D. Friedman. 1994. Helicobacter pylori infection and gastric lymphoma. N. Engl. J. Med. 330:1267-1271.
23. Phadnis, S. H., M. H. Parlow, M. Levy, D. Ilver, C. M. Caulkins, J. B. Connors, and B. E. Dunn. 1996. Surface localization of Helicobacter pylori urease and a heat shock proteIn homolog requires bacterial autolysis. Infect. Immun. 64:905-912.
24. Shimizu, T., T. Akamatsu, A. Sugiyama, H. Ota, and T. Katsuyama. 1996. Helicobacter pylori and the surface mucous gel layer of the human stomach. Helicobacter 1:207-218.
25. Smith, D. G. E., W. C. Russell, W. J. Ingledew, and D. Thirkell. 1993. Hydrolysis of urea by Ureaplasma urealyticum generates a transmembrane potential with resultant ATP synthesis. J. Bacteriol. 175:3253-3258.
26. Stuart-Tilley, A., C. Sardet, J. Pouyssegur, M. A. Schwartz, D. Brown, and S. L. Alper. 1994. Immunolocalization of anion exchanger AE2 and cation exchanger NHE-1 In distinct adjacent cells of gastric mucosa. Am. J. Physiol. 266:C559-C568.
27. Tomb, J. F., O. White, A. R. Kerlavage, R. A. Clayton, G. G. Sutton, R. D. Fleischmann, K. A. Ketchum, H. P. Klenk, S. Gill, B. A. Dougherty, K. Nelson, J. Quackenbush, L. Zhou, E. F. Kirkness, S. Peterson, B. Loftus, D. Richardson, R. Dodson, H. G. Khalak, A. Glodek, K. McKenney, L. M. Fitzegerald, N. Lee, M. D. Adams, E. K. Hickey, D. E. Berg, J. D. Gocayne, T. R. Utterback, J. D. Peterson, J. M. Kelley, M. D. Cotton, J. M. Weidman, C. Fujii, C. Bowman, L. Watthey, E. Wallin, W. S. Hayes, M. Borodovsky, P. D. Karp, H. O. Smith, C. M. Fraser, and J. C. Venter. 1997. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388: 539-547.
28. Tsuda, M., M. Karita, M. G. Morshed, K. Okita, and T. Nakazawa. 1994. A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach. Infect. Immun. 62:3586-3589.
29. Warren, J. R., and B. Marshall. 1983. Unidentified curved bacilli on gastric epithelium In active chronic gastritis. Lancet i:1273-1275.
30. Wotherspoon, A. C., C. Ortiz-Hidalgo, M. R. Falzon, and P. G. Isaacson. 1991. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet 338:1175-1176.