Correction of autoimmune lymphoproliferative syndrome by bone marrow transplantation

Bone Marrow Transplantation

Volumn 22, Issue 4, 1998, Pages 375-380

  Sleight, B J ^a,c   Prasad, V S ^b   DeLaat, C ^a   Steele, P ^b   Ballard, E ^a   Arceci, R J ^a   Sidman, C L ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmune lymphoproliferative syndrome; Fas gene defects; Lymphoma; Lymphoproliferative disorder

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYCLOSPORIN A; FAS ANTIGEN;

ARTICLE; AUTOIMMUNITY; BONE MARROW TRANSPLANTATION; CASE REPORT; CONTROLLED STUDY; DRUG CYTOTOXICITY; EXON; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; INFANT; LYMPHADENOPATHY; LYMPHOCYTE PROLIFERATION; LYMPHOPROLIFERATIVE DISEASE; MALE; NONHODGKIN LYMPHOMA; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; T LYMPHOCYTE;

EID: 0031707361     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701306     Document Type: Article

References (20)

1. Owen JJ, Jenkinson EJ. Apoptosis and T-cell repertoire selection in the thymus. Ann NY Acad Sci 1992; 663: 305-310.
2. + T cell population bearing a distinctive β chain in MRL lpr/lpr mice suggests a role for the fas protein in peripheral T cell selection. Eur J Immunol 1994; 24: 2761-2766.
3. Sidman CL, Marshall JD, von Boehmer H. Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice. Eur J Immunol 1992; 22: 499-504.
4. Lichter P, Walczak H, Weitz S et al. The human APO-1 (APT) antigen maps to 10q23, a region that is syntenic with mouse chromosome 19. J Immunol 1992; 14: 179-180.
5. Inazawa J, Itoh H, Abe T, Nagata S. Assignment of the human Fas antigen gene (FAS) to 10q24.1. Genomics 1992; 14: 821-822.
6. Cheng J, Liu C, Koopman J, Mountz JD. Characterization of human fas gene. Exon/intron organization and promotor region. J Immunol 1995; 154: 1239-1245.
7. Itoh N, Yonehara S, Ishii A et al. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991; 66: 233-243.
8. Watanabe-Fukunaga R, Brannan CI, Copeland NG et al. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992; 356: 314-317.
9. Adachi M, Watanabe-Fukunaga RW, Nagata S. Aberrant transcription caused by the insertion of an early transposable element of an intron of the Fas antigen gene of lpr mice. Proc Natl Acad Sci USA 1993; 90: 1756-1760.
10. Takahashi T, Tanaka M, Brannan CI et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas Ligand. Cell 1994; 76: 969-976.
11. Rieux-Laucat F, Le Deist F, Hivroz C et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995; 268: 1347-1349.
12. Fisher GH, Rosenberg FJ, Straus SE et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 1995; 81: 935-946.
13. Drappa J, Vaishnaw AK, Sullivan KE et al Fas gene mutations in the Canale - Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity. New Engl J Med 1996; 335: 1643-1649.
14. Miller G, Lipman M. Release of infectious Epstein - Barr virus by transformed marmoset leukocytes. Proc Natl Acad Sci USA 1973; 70: 190-194.
15. Murphy ED, Roths JB. A single gene model for massive lymphoproliferation with immune complex disease in new mouse strain MRL. Topics in Hematology: Proceeding of the 16th International Congress of Hematology, Kyoto, Japan, 1976, pp 69-72.
16. Moscovitch M, Rosenmann E, Neeman Z, Slavin S. Successful treatment of autoimmune manifestations in MRL/1 and MRL/n mice using total lymphoid irradiation (TLI). Exp Mol Pathol 1983; 38: 33-47.
17. Allen RD, Marshall JD, Roths JB, Sidman CL. Bone marrow transplantation from mutant lpr/lpr mice. Functional abnormalities rather than alloantigenic differences appear to determine the development of a graft-vs.-host-like syndrome. Eur J Immunol 1990; 20: 2057-2066.
18. Izui S, Kelley VE, Masuda K et al. Induction of various auto-antibodies by mutant gene lpr in several strains of mice. J Immunol 1984; 133: 227.
19. Morse HC, Roths JB, Davidson WF et al. Abnormalities induced by the mutant gene, lpr. Patterns of disease and expression of murine leukemia viruses in SJL/J mice homozygous and heterozygous for lpr. J Exp Med 1985; 161: 602-616.
20. Ogatta Y, Kimura M, Shimada K et al. Distinctive expression of lpr in the heterozygous state on different genetic backgrounds. Cell Immunol 1993; 148: 91-102.