Moderate doses of intraoperative radiation severely suppress early strength of anastomoses in the rat colon

Radiation Research

Volumn 150, Issue 4, 1998, Pages 431-435

  Hendriks, T ^a   Wobbes, T ^a   De Man, B M ^a   Hoogenhout, J ^a   Seifert, W F ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CANCER SURGERY; COLON ANASTOMOSIS; COLON CANCER; IRRADIATION; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RAT; WOUND HEALING;

ANASTOMOSIS, SURGICAL; ANIMALS; COLON; COLONIC NEOPLASMS; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, RADIATION; INTRAOPERATIVE PERIOD; MALE; RADIOTHERAPY DOSAGE; RATS; RATS, WISTAR;

EID: 0031707144     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579662     Document Type: Article

References (25)

1. B. J. Cummings, Adjuvant radiation therapy for colorectal cancer. Cancer 70, 1372-1383 (1992).
2. B. D. Minsky, The role of adjuvant radiation therapy in the treatment of colorectal cancer. Hematol. Oncol. Clin. N. Am. 11, 679-697 (1997).
3. L. L. Gunderson, Past, present and future of intraoperative irradiation for colorectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 34, 741-744 (1996).
4. O. Abuchaibe, F. A. Calvo, I. Azinovic, J. Aristu, F. Pardo and J. Alvarez-Cienfuegos, Intraoperative radiotherapy in locally advanced recurrent colorectal cancer. Int. J. Radiat. Oncol. Biol. Phys. 26, 859-867 (1993).
5. E. Bussieres, F. N. Gilly, P. Rouanet, M. A. Mahé, A. Roussel, M. Delannes, J. P. Gérard and J. B. Dubois, Recurrences of rectal cancers: Results of a multimodal approach with intraoperative radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 34, 49-56 (1996).
6. L. L. Gunderson, H. Nelson, J. A. Martenson, S. Cha, M. Haddock, R. Devine, J. M. Fieck, B. Wolff, R. Dozois and M. J. O'Connell, Locally advanced primary colorectal cancer: Intraoperative electron and external beam irradiation ± 5-FU. Int. J. Radiat. Oncol. Biol. Phys. 37, 601-614 (1997).
7. K. M. Tveit, J. N. Wiig, D. R. Olsen, A. Storaas, J. P. Poulsen and K. E. Giercksky, Combined modality treatment including intraoperative radiotherapy in locally advanced and recurrent rectal cancer. Radiother. Oncol. 44, 277-282 (1997).
8. C. G. Willet, P. C. Shellito, J. E. Tepper, R. Eliseo, K. Convery and W. C. Wood, Intraoperative electron beam irradiation therapy for primary locally advanced rectal and rectosigmoid carcinoma. J. Clin. Oncol. 9, 843-849 (1991).
9. M. K. Tibbs, Wound healing following radiation therapy: A review. Radiother. Oncol. 42, 99-106 (1997).
10. L. P. Fielding, S. Stewart-Brown, L. Blesovsky and G. Kearny, Anastomotic integrity after operation for large bowel cancer: A multicentre study. Br. Med. J. 281, 411-414 (1980).
11. M. Turunen and P. Peltokallio, Surgical results in 657 patients with colorectal cancer. Dis. Colon Rectum 26, 606-612 (1983).
12. T. Hendriks and W. J. B. Mastboom, Healing of experimental intestinal anastomoses: Parameters for repair. Dis. Colon Rectum 33, 891-901 (1990).
13. W. F. Seifert, T. Wobbes, J. Hoogenhout, B. M. de Man, K. M. L. C. Huyben and T. Hendriks, Intraoperative irradiation delays anastomotic repair in rat colon. Am. J. Surg. 170, 256-261 (1995).
14. J. W. D. de Waard, T. Wobbes, B. M. de Man, C. J. van der Linden and T. Hendriks, Post-operative levamisole may compromise early healing of experimental intestinal anastomoses. Br. J. Cancer 72, 456-460 (1995).
15. T. K. Hunt, Comment. In Wound Healing and Wound Infection: Theory and Surgical Practice (T. K. Hunt, Ed.), pp. 192-193. Appleton-Century-Crofts, New York, 1980.
16. M. J. Koruda and R. H. Rolandelli, Experimental studies on the healing of colonie anastomoses. J. Surg. Res. 48, 504-515 (1990).
17. S. Weiber, H. Jiborn and B. Zederfeldt, Preoperative irradiation and colonic healing. Eur. J. Surg. 160, 47-51 (1994).
18. J. Biert, J. Hoogenhout, T. Wobbes and T. Hendriks, High-dose preoperative irradiation without detrimental effect on early repair of anastomoses in the colon of the rat. Radiat. Res. 147, 362-368 (1997).
19. J. M. Dominguez, S. M. Jakate, N. J. Speziale, M. H. Savin, W. E. Altringer and T. J. Saclarides, Intestinal anastomotic healing at varying times after irradiation. J. Surg. Res. 61, 293-299 (1996).
20. T. J. Saclarides, D. A. Rohrer, A. K. Bhattacharyya and M. S. Bapna, Effect of intraoperative radiation on the tensile strength of small bowel anastomoses. Dis. Colon Rectum 35, 151-157 (1992).
21. V. Vegesna, W. H. McBride, J. M. G. Taylor and H. R. Withers, The effect of interleukin-1β or transforming growth factor-β on radiation-impaired murine skin wound healing. J. Surg. Res. 59, 699-704 (1995).
22. S. Takahashi, M. Sugimoto, Y. Kotoura, N. Nishimatsu, Y. Shibamoto, M. Abe and T. Yamamuro, The effects of intraoperative radiotherapy on bone-healing ability in relation to different doses and postradiotherapy intervals. Int. J. Radiat. Oncol. Biol. Phys. 30, 1147-1152 (1994).
23. J. E. Tepper, W. Sindelar, E. L. Travis, R. Terrill and T. Padikal, Tolerance of canine anastomoses to intraoperative radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 9, 987-992 (1983).
24. M. G. Buell and R. K. Harding, Proinflammatory effects of local abdominal irradiation on rat gastrointestinal tract. Digest. Dis. Sci. 34, 390-399 (1989).
25. W. F. Seifert, T. Wobbes, J. Hoogenhout, B. M. de Man and T. Hendriks, Intra-operative irradiation prolongs the presence of matrix metalloproteinase activity in large bowel anastomoses of the rat. Radiat. Res. 147, 354-361 (1997).