Phosphorylation of cytosolic phospholipase A2 by IL-3 is associated with increased free arachidonic acid generation and leukotriene C4 release in human basophils

Journal of Allergy and Clinical Immunology

Volumn 102, Issue 3, 1998, Pages 512-520

  Miura, Katsushi ^a   Hubbard, Walter C ^a   MacGlashan Jr , Donald W ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Arachidonic acid; Cytosolic phospholipase A2; Human basophils; IL 3; Leukotriene C4

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 4 O METHYLPHORBOL 13 ACETATE 12 MYRISTATE; ANAPHYLATOXIN; COMPLEMENT COMPONENT C5A; INTERLEUKIN 3; IONOMYCIN; LEUKOTRIENE C4; PHOSPHOLIPASE A2;

ARACHIDONIC ACID METABOLISM; ARTICLE; BASOPHIL; CYTOKINE RELEASE; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MASS SPECTROMETRY; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

EID: 0031704440     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(98)70142-3     Document Type: Article

References (37)

1. MacGlashan DW Jr, Hubbard WC. Interleukin-3 alters free arachidonic acid generation in C5a-stimulated human basophils. J Immunol 1993;151:6358-69.
2. Kurimoto Y, de Weck AL, Dahinden CA. The effect of interleukin 3 upon IgE-dependent and IgE-independent basophil degranulation and leukotriene generation. Eur J Immunol 1991;21:361-8.
3. Schleimer RP, Derse CP, Friedman B, Gillis S, Flaut M, Lichtenstein LM, et al. Regulation of human basophil mediator release by cytokines. I. Interaction with antiinflammatory steroids. J Immunol 1989;143:1310-7.
4. Brunner T, Heusser CH, Dahinden CA. Human peripheral blood basophils primed by interleukin-3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation. J Exp Med 1993;177:605-11.
5. MacGlashan DW Jr, White JM, Huang SK, Ono SJ, Schroeder J, Lichtenstein LM. Secretion of interleukin-4 from human basophils: the relationship between IL-4 mRNA and protein in resting and stimulated basophils. J Immunol 1994;152:3006-16.
6. MacGlashan DW Jr, Warner JA. Stimulus-dependent leukotriene release from human basophils: a comparative study of C5a and Fmet-leu-phe. J Leukoc Biol 1991;49:29-40.
7. Yamaguchi M, Hirai K, Ohta K, Suzuki K, Kitani S, Takaishi T, et al. Culturing in the presence of IL-3 converts anti-IgE nonresponding basophils into responding basophils. J Allergy Clin Immunol 1996;97:1279-87.
8. Kurimoto Y, de Weck AL, Dahinden CA. Interleukin 3-dependent mediator release in basophils triggered by C5a. J Exp Med 1989;170:467-79.
9. Steinhiblber D. 5-lipoxygenase: expression and regulation of activity. Pharm Acta Helv 1994;69:3-14.
10. 2 activity and leukotriene C4 release. J Pharm Exp Ther 1998;284:847-57.
11. Lin LL, Wartmann M, Lin A, Knoph JL, Seth A, Davis RJ. cPLA2 is phosphorylated and activated by MAP kinase. Cell 1993;72:269-78.
12. Clark JD, Lin LL, Kriz RW, Ramesha CS, Sultzman LA, Lin AY, et al. A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP. Cell 1991;65:1043-51.
13. Sharp JD, White DL, Chiou XG, Goodson T, Gamboa GC, McClure D, et al. Molecular cloning and expression of human Ca2+-sensitive cytosolic phospholipase A2. J Biol Chem 1991;266:14850-3.
14. Leslie CC, Voelker DR, Channon JY, Wall MM, Zelarney PT. Properties and purification of an arachidonoyl-hydrolyzing phospholipase A2 from a macrophage cell line, RAW 264.7. Biochim Biophys Acta 1988;963:476-92.
15. Diez E, Louis-Flamberg P, Hall RH, Mayer RJ. Substrate specificities and properties of human phospholipase A2 in a mixed vesicle model. J Biol Chem 1992;267:18342-8.
16. Serhan CN, Haeggstrom JZ, Leslie CC. Lipid mediator networks in cell signaling: update and impact of cytokines. FASEB J 1996;10:1147-58.
17. Clark JD, Schievella AR, Nalefski EA, Lin L-L. Cytosolic phospholipase A2. J Lipid Mediat Cell Signal 1995;12:83-117.
18. Wijkander J, Dundler R. Macrophage arachidonate-mobilizing phospholipase A2: role of Ca2+ for membrane binding but not for catalytic activity. Biochem Biophys Res Commun 1992;184:118-24.
19. Nalefski EA, Sultzman LA, Martin DM, Kriz RW, Towler PS, Knopf JL, et al. Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca-dependent lipid binding domain and a Ca-independent catalytic domain. J Biol Chem 1994;269:18239-49.
20. Channon JY, Leslie CC. A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A with membrane in the macrophage cell line RAW 264.7. J Biol Chem 1990;265:5409-13.
21. Lin L-L, Lin AY, Knopf JL. Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid. Proc Natl Acad Sci USA 1992;89:6147-51.
22. Qiu Z-H, de Carvalho MS, Leslie CC. Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophages. J Biol Chem 1993;268:24506-13.
23. Kramer RM, Roberts EF, Hyslop PA, Utterback BG, Hui KY, Jakubow-ski JA. Differential activation of cytosolic phospholipase A2 (cPLA2) by thrombin and thrombin receptor agonist peptide in human platelets. Evidence for activation of cPLA2 independent of mitogen-activated protein kinases ERK1/2. J Biol Chem 1995;270:14816-23.
24. Nemenoff RA, Winitz S, Qian N-X, Putten VV, Johnson GL, Heasley LE. Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule protein 2 kinase and protein kinase C. J Biol Chem 1993;268:1960-4.
25. Xing M, Mattera R. Phosphorylation-dependent regulation of phospholipase A2 by G-proteins and Ca2+ in HL60 granulocytes. J Biol Chem 1992;267:25966-75.
26. Xu X-X, Rock CO, Qiu Z-H, Leslie CC, Jackowski S. Regulation of cytosolic phospholipase A2 phosphorylation and eicosanoid production by colony-stimulating factor 1. J Biol Chem 1994;269:31693-700.
27. Gilbert HS, Ornstein L. Basophil counting with a new staining method using alcian blue. Blood 1975;46:279-86.
28. MacGlashan DW Jr. Single-cell analysis of Ca++ changes in human lung mast cells: graded vs. all-or-nothing elevations after IgE-mediated stimulation. J Cell Biol 1989;109:123-34.
29. Hubbard WC, Litteist CL, Liu MC, Bleecher ER, Eggleston JC, Mckensie TC, et al. Profiling of prostaglandin biosynthesis in biopsy fragments of human lung carcinoma and normal human lung by capillary gas chromatography-negative ion chemical ionization mass spectrometry. Prostaglandins 1986;32:889-906.
30. MacGlashan DW Jr, Peters SP, Warner J, Lichtenstein LM. Characteristics of human basophil sulfidopeptide leukotriene release: releasability defined as the ability of the basophil to respond to dimeric crosslinks. J Immunol 1986;136:2231-9.
31. Hayes EC, Lombarde DL, Girard Y. Measuring leukotrienes of slow-reacting substance of anaphylaxis: development of a specific radioimmunoassay. J Immunol 1983;131:429-33.
32. Warner JA, Peters SP, Lichtenstein LM, Hubbard W, Yancey KB, Stevenson HC, et al. Differential release of mediators from human basophils: differences in arachidonic acid metabolism following activation by unrelated stimuli. J Leukoc Biol 1989;45:558-71.
33. Bokoch GM. Chemoattractant signaling and leukocyte activation. Blood 1995;86:1649-60.
34. Okuda K, Sanghera JS, Pelech SL, Kanakura Y, Hallek M, Griffin JD, et al. Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase. Blood 1992;79:2880-7.
35. Bittorf T, Jaster R, Brock J. Rapid activation of the MAP kinase pathway in hematopoietic cells by erythropoietin, granulocyte-macrophage colony stimulating factor and interleukin-3. Cell Signal 1994;6:305-11.
36. Balboa MA, Balsinde J, Winstead MV, Tischfield JA, Dennis EA. Novel group V phospholipase A2 involved in arachidonic acid mobilization in murine P388D1 macrophages. J Biol Chem 1996;271:32381-4.
37. 1 Cells. J Biol Chem 1993;268:21875-82.