Total synthesis and stereochemistry of cytoblastin

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 8, 1998, Pages 1243-1254

  Moreno, Ofir A ^a   Kishi, Yoshito ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Cytoblastin; Natural products; Protein kinase C; Tumor promoters

Indexed keywords

CYTOBLASTIN; DIACYLGLYCEROL; INDOLACTAM V; INDOLE DERIVATIVE; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; STEREOCHEMISTRY;

CARCINOGENS; INDOLES; LACTAMS; STEREOISOMERISM;

EID: 0031704435     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00113-8     Document Type: Article

References (33)

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31. We are indebted to Drs. Kumagai and Naganawa at Microbial Chemistry Research Foundation for a sample of natural cytoblastin.
32. MacroModel version 45 provided courtesy of Professor Still, Columbia University Minimizations were performed on a Silicon Graphics Indigo workstation.
33. Assays performed by Professor Rando at Harvard Medical School and by Dr Gusovsky at Eisai Research Institute.