Characteristic immunolocalization of Ku protein as nuclear matrix

Hybridoma

Volumn 17, Issue 5, 1998, Pages 413-420

  Yu, Eunsil ^a   Song, Kyuyoung ^a   Moon, Heebom ^a   Maul, Gerd G ^b   Lee, Inchul ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; NUCLEAR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS MATRIX; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYBRIDOMA; IMMUNOBLOTTING; LYMPHOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SCID MOUSE; THYMUS; TISSUE DISTRIBUTION; XENOTRANSPLANTATION;

ANIMALIA;

EID: 0031703694     PISSN: 0272457X     EISSN: None     Source Type: Journal    
DOI: 10.1089/hyb.1998.17.413     Document Type: Article

References (47)

1. Berezney R, and Coffey DS: Identification of a nuclear protein matrix. Biochem Biophys Res Commun 1974;60:1410-1417.
2. Comings DE, and Okada TA: Nuclear proteins. III. The fibrillar nature of nuclear matrix. Exp Cell Res 1976;103:341-360.
3. Berezney R, and Coffey DS: Nuclear protein matrix: Association with newly synthesized DNA. Science 1975;189:291-293.
4. Faiferman I, and Pogo AO: Isolation of a nuclear ribonucleoprotein network that contains heterogeneous RNA and is bound to the nuclear envelope. Biochemistry 1975;14:3808-3815.
5. Herman R, Weymouth L, and Penman S: Heterogeneous nuclear RNA-protein fibers in chromatin-depleted nuclei. J Cell Biol 1978;78:663-674.
6. Herlan G, Eckert WA, Kaffenberger W, and Wunderlich F: Isolation and characterization of an RNA-containing nuclear matrix from tetrahymena macronuclei. Biochemistry 1979;18:1782-1788.
7. Mirkovitch J, Mirault M-E, and Laemmli UK: Organization of the higher-order chromatin loop: Specific attachment sites on nuclear scaffold. Cell 1984;39:223-232.
8. Berezney R, and Coffey DS: Nuclear matrix: Isolation and characterization of a framework structure from rat liver nuclei. J Cell Biol 1977;73:616-637.
9. Gasser SM, and Laemmli UK: A glimpse at chromosomal order. Trends Genet 1987;3:16-22.
10. Staufenbiel M, and Deppert W: Preparation of nuclear matrices from cultured cells: Subfractionation of nuclei in situ. J Cell Biol 1984;98:1886-1894.
11. Fey EG, Wan KM, and Penman S: Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition. J Cell Biol 1984;98:1973-1984.
12. Mimori T, Akizuki M, Yamagata H, Inada S, Yoshida S, and Homma M: Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies from patients with polymyositis-scleroderma overlap. J Clin Invest 1981;68:611-620.
13. Reeves WH: Use of monoclonal antibodies for the characterization of novel DNA-binding proteins recognized by human autoimmune sera. J Exp Med 1985;161:18-39.
14. Yaneva M, and Busch H: A 10S particle released from deoxyribonuclease-sensitive regions of HeLa cell nuclei contains the 86-kilodalton-70-kilodalton protein complex. Biochemistry 1986;25: 5057-5063.
15. Mimori T, and Hardin JA: Mechanism of interaction of Ku protein and DNA. J Biol Chem 1986;261:10375-10379.
16. Bilier PR, Griffith AJ, Craft J, and Hardin JA: Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. J Biol Chem 1993;268:7594-7601.
17. Falzon M, Fewell JW, and Kuff EL: EPB-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand translation in DNA. J Biol Chem 1993;268: 10546-10552.
18. Tuteja N, Tuteja R, Ochem A, Taneja P, Guang N, Simoncsits A, Susie S, Rahman K, Murasic L, Chen J, Zhang J, Wang S, Pongor S, and Falaschi A: Human DNA helicase II: A novel DNA unwinding enzyme identified as the Ku autoantigen. EMBO J 1994;13:4991-5001.
19. Lees-Miller SP, Chen YR, and Anderson CW: Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku antigen. Mol Cell Biol 1990;10:6472-6481.
20. Dvir A, Peterson SR, Knuth MW, Lu H, and Dynan WS: Ku antigen is a regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. Proc Natl Acad Sci USA 1992;89:11920-11924.
21. Anderson CW, and Lees-Miller SP: The nuclear serine/threonine protein kinase DNA-PK. Crit Rev Eukaryot Gene Expr 1992;2: 283-314.
22. Gottlieb TM, and Jackson SP: The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen. Cell 1993;72:131-142.
23. Suwa A, Hirakata M, Takeda Y, Jesch SA, Mimori T, and Hardin JA: DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA. Proc Natl Acad Sci USA 1994;91:6904-6908.
24. Morozov VE, Falzon M, Amderson CW, and Kuff EL: DNA-dependent protein kinase is activated by nicks and larger single-stranded gaps. J Biol Chem 1994;269:16684-16688.
25. Kharbanda S, Pandey P, Jin S, Inoue S, Bharti A, Yuan ZM, Weichselbaum R, Weaver D, and Kufe D: Functional interaction between DNA-PK and c-Abl in response to DNA damage. Nature 997;386:732-735.
26. Getts RC, and Stamato TD: Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant. J Biol Chem 1994;269:15982-15984.
27. Smider V, Kimryn-Rathmell W, Lieber MR, and Gilbert C: Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science 1994;266:288-291.
28. Tacciaoli GE, Goulieb TM, Blunt T, Proestley A, Demengeot J, Mizuta R, Lehmann AR, Alt FW, Jackson SP, and Jeggo PA: Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 1994;265:1442-1445.
29. Lees-Miller SP, Godbout R, Chan DW, Weinfeld M, Day RSIII, Barron GM, and Allalunis-Turner J: Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science 1995;267:1183-1185.
30. Blunt T, Finnie NJ, Taccioli GE, Smith GCM, Demengeot J, Gottlieb T, Mizuta R, Varghese AJ, Alt FW, Jeggo PA, and Jackson SP: Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the mouse scid mutation. Cell 1995;80:813-823.
31. Kirschgessner CU, Patil CK, Evans JW, Cuomo DA, Fried LM, Carter T, Oettinger MA, and Brown JM: DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science 1995;267:1178-1183.
32. Fey EG, and Penman S: Nuclear matrix proteins reflect cell type of origin in cultured human cells. Proc Natl Acad Sci USA 1988;85:121-125.
33. He D, Nickerson JA, and Penman S: Core filament of nuclear matrix. J Cell Biol 1990;110:569-579.
34. Kohler G, and Milstein G: Continuous cultures of fused cells secreting antibody probes. Proc Natl Acad Sci USA 1983;80: 1194-1198.
35. Reeves WH, Sthoeger ZM: Molecular cloning of cDNA encoding the p70 (Ku) lupus autoantigen. J Biol Chem 1989;264:5047-5052.
36. Nakayasu H, and Berezney R: Nuclear matrins: Identification of the major nuclear matrix proteins. Proc Natl Acad Sci USA 1991;88:10312-10316.
37. Chaly N, Bladon T, Setterfield G, Little JE, Kaplan JG, and Brown DL: Changes in distribution of nuclear matrix antigens during the mitotic cell cycle. J Cell Biol 1984;99:661-671.
38. Lehner CF, Eppenberger HM, Fakan S, and Nigg EA: Nuclear substructure antigens. Monoclonal antibodies against components of nuclear matrix preparations. Exp Cell Res 1986;162:205-219.
39. Noaillac-Depeyre J, Azum M, Geraud M, Mathieu C, and Gas N: Distribution of nuclear matrix proteins in interphase CHO cells and rearrangements during the cell cycle: An ultrastructural study. Biol Cell 1987;61:23-32.
40. Berezney R: Organization and functions of the nuclear matrix. In: Chromosomal Nonhistone Proteins. Hnilica LS (Ed.), Vol. IV, CRC Press, Boca Raton, FL, 1984, pp. 119-180.
41. Allaway GP, Vivino AA, Kohn LD, Notkins LA, and Prabhakar BS: Characterization of the 70 kDa component of the human Ku autoantigen expressed in insect cell nuclei using a baculovirus vector. Biochem Biophys Res Commun 1990;168:747-755.
42. Yaneva M, and Jhiang S: Expression of the Ku protein during cell proliferation. Biochim Biophys Acta 1991;1090:181-187.
43. Wang J, Satoh M, Pierani A, Schmitt J, Chou C, Stunnenberg HG, Roeder RG, and Reeves WH: Assembly and DNA binding of recombinant Ku (p70/p80) autoantigen defined by a novel monoclonal antibody specific for p70/p80 heterodimers. J Cell Sci 1994;107:3223-3233.
44. Fewell JW, and Kuff EL: Intracellular redistribution of Ku immunoreactivity in response to cell-cell contact and growth modulating components in the medium. J Cell Sci 1996;109:1937-1946.
45. Higashiura M, Shimizu Y, Tanimoto M, Morita T, and Yagura T: Immunolocalization of Ku-proteins (p80/p70): localization of p70 to nucleoli and periphery of both interphase nuclei and metaphase chromosomes. Exp Cell Res 1992;201:444-451.
46. Getzenberg RH, Pienta KJ, Huang EYW, Murphy BC, and Coffey DS: Modification of the intermediate filament and nuclear matrix networks by the extracellular matrix. Biochem Biophys Res Commun 1991;179:340-344.
47. Replogle-Schwab TS, Gezenberg RH, Donat TL, and Pienta KJ: Effects of organ site on nuclear matrix protein composition. J Cell Biochem 1996;62:132-141.