메뉴 건너뛰기




Volumn 358, Issue 6, 1998, Pages 649-656

Effects of an antiarrhythmic drug A-2545 on canine ventricular arrhythmia models; comparison with mexiletine and flecainide

Author keywords

A 2545; Dog; Flecainide; Mexiletine; Programmed electrical stimulation; Ventricular arrhythmia

Indexed keywords

ADRENALIN; DIGITALIS; FLECAINIDE; MEXILETINE; N3 (2,2,5,5 TETRAMETHYL 3 PYRROLINYL 3 CARBOXAMIDO)PROPYLPHTHALIMIDE; UNCLASSIFIED DRUG;

EID: 0031700658     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005307     Document Type: Article
Times cited : (7)

References (30)
  • 1
    • 0028819771 scopus 로고
    • Acute antiarrhythmic effects of intravenously administered amiodarone on canine ventricular arrhythmia
    • Awaji T, Wu ZJ, Hashimoto K (1995) Acute antiarrhythmic effects of intravenously administered amiodarone on canine ventricular arrhythmia. J Cardiovasc Pharmacol 26:869-878
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 869-878
    • Awaji, T.1    Wu, Z.J.2    Hashimoto, K.3
  • 2
    • 0001127258 scopus 로고
    • An analysis of the time relations of electrocardiogram
    • Bazett HC (1918) An analysis of the time relations of electrocardiogram. Heart 7:353-370
    • (1918) Heart , vol.7 , pp. 353-370
    • Bazett, H.C.1
  • 3
    • 0029761233 scopus 로고    scopus 로고
    • Effects of dofetilide, a class III antiarrhythmic drug, on various ventricular arrhythmias in dogs
    • Chen JG, Xue YX, Eto K, Ni C, Hashimoto K (1996) Effects of dofetilide, a class III antiarrhythmic drug, on various ventricular arrhythmias in dogs. J Cardiovasc Pharmacol 28:576-584
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 576-584
    • Chen, J.G.1    Xue, Y.X.2    Eto, K.3    Ni, C.4    Hashimoto, K.5
  • 4
    • 0000080398 scopus 로고
    • New table for multiple comparisons with a control
    • Dunnett C (1963) New table for multiple comparisons with a control. Biometrics 19:482-491
    • (1963) Biometrics , vol.19 , pp. 482-491
    • Dunnett, C.1
  • 5
    • 0019991255 scopus 로고
    • Ventricular activation patterns of spontaneous and induced ventricular rhythms in canine one-day-old myocardial infarction: Evidence for focal and reentrant mechanisms
    • El-Sherif N, Mehra R, Gough WB, Zeiler RH (1982) Ventricular activation patterns of spontaneous and induced ventricular rhythms in canine one-day-old myocardial infarction: evidence for focal and reentrant mechanisms. Circ Res 51:152-166
    • (1982) Circ Res , vol.51 , pp. 152-166
    • El-Sherif, N.1    Mehra, R.2    Gough, W.B.3    Zeiler, R.H.4
  • 6
    • 0015908242 scopus 로고
    • Spontaneous and induced cardiac arrhythmias in subendocardial Purkinje fibers surviving extensive myocardial infarction in dogs
    • Friedman PL, Stewart JR, Wit AL (1973) Spontaneous and induced cardiac arrhythmias in subendocardial Purkinje fibers surviving extensive myocardial infarction in dogs. Circ Res 33:612-626
    • (1973) Circ Res , vol.33 , pp. 612-626
    • Friedman, P.L.1    Stewart, J.R.2    Wit, A.L.3
  • 7
    • 0022478580 scopus 로고
    • New antiarrhythmic agents. 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamides and 2,2,5,5-tetramethylpyrrolidine-3-carboxamides
    • Hankovszky OH, Hideg K, Bodi I, Frank L (1986) New antiarrhythmic agents. 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamides and 2,2,5,5-tetramethylpyrrolidine-3-carboxamides. J Med Chem 29:1138-1152
    • (1986) J Med Chem , vol.29 , pp. 1138-1152
    • Hankovszky, O.H.1    Hideg, K.2    Bodi, I.3    Frank, L.4
  • 8
    • 0027480449 scopus 로고
    • Antiarrhythmic effects of bisaramil in canine models of ventricular arrhythmia
    • Haruno A, Hashimoto K (1993) Antiarrhythmic effects of bisaramil in canine models of ventricular arrhythmia. Eur J Pharmacol 233:1-6
    • (1993) Eur J Pharmacol , vol.233 , pp. 1-6
    • Haruno, A.1    Hashimoto, K.2
  • 9
    • 0015345599 scopus 로고
    • The mechanism of sensitization of the ventricle to epinephrine by halothane
    • Hashimoto K, Hashimoto K (1972) The mechanism of sensitization of the ventricle to epinephrine by halothane. Am Heart J 83:652-658
    • (1972) Am Heart J , vol.83 , pp. 652-658
    • Hashimoto, K.1    Hashimoto, K.2
  • 10
    • 0021362942 scopus 로고
    • Antiarrhythmic plasma concentrations of mexiletine on canine ventricular arrhythmias
    • Hashimoto K, Ishii M, Komori S (1984) Antiarrhythmic plasma concentrations of mexiletine on canine ventricular arrhythmias. J Cardiovasc Pharmacol 6:213-219
    • (1984) J Cardiovasc Pharmacol , vol.6 , pp. 213-219
    • Hashimoto, K.1    Ishii, M.2    Komori, S.3
  • 11
    • 0021855145 scopus 로고
    • Canine digitalis arrhythmia as a model for detecting Na-channel blocking antiarrhythmic drugs: A comparative study using other canine arrhythmia models and the new antiarrhythmic drugs, propafenone. tocanide and SUN 1165
    • Hashimoto K, Ishii M, Komori S, Mitsuhashi H (1985) Canine digitalis arrhythmia as a model for detecting Na-channel blocking antiarrhythmic drugs: a comparative study using other canine arrhythmia models and the new antiarrhythmic drugs, propafenone. tocanide and SUN 1165. Heart Vessels 1:29-35
    • (1985) Heart Vessels , vol.1 , pp. 29-35
    • Hashimoto, K.1    Ishii, M.2    Komori, S.3    Mitsuhashi, H.4
  • 12
    • 0025746309 scopus 로고
    • Effects of antiarrhythmic drugs on canine ventricular arrhythmia models: Which electrophysiological characteristics of drugs are related to their effectiveness?
    • Hashimoto K, Haruno A, Matsuzaki T, Sugiyama A, Akiyama K (1991a) Effects of antiarrhythmic drugs on canine ventricular arrhythmia models: which electrophysiological characteristics of drugs are related to their effectiveness? Cardiovasc Drugs Ther 5:805-818
    • (1991) Cardiovasc Drugs Ther , vol.5 , pp. 805-818
    • Hashimoto, K.1    Haruno, A.2    Matsuzaki, T.3    Sugiyama, A.4    Akiyama, K.5
  • 14
    • 0025316066 scopus 로고
    • Electrophysiologic effects of E-4031, a class III antiarrhythmic agent, on re-entrant ventricular arrhythmias in a canine 7-day-old myocardial infarction model
    • Katoh H, Ogawa S, Furuno I, Sato Y, Yoh S, Saeki K, Nakumura Y (1990) Electrophysiologic effects of E-4031, a class III antiarrhythmic agent, on re-entrant ventricular arrhythmias in a canine 7-day-old myocardial infarction model. J Pharmacol Exp Ther 253:1077-1082
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 1077-1082
    • Katoh, H.1    Ogawa, S.2    Furuno, I.3    Sato, Y.4    Yoh, S.5    Saeki, K.6    Nakumura, Y.7
  • 15
    • 0027407161 scopus 로고
    • Effects of flecainide and d-sotalol on myocardial conduction and refractoriness: Relation to antiarrhythmic and proarrhythmic drug effects
    • Kidwell GA, Gonzalez MD (1993) Effects of flecainide and d-sotalol on myocardial conduction and refractoriness: relation to antiarrhythmic and proarrhythmic drug effects. J Cardiovasc Pharmacol 21:621-632
    • (1993) J Cardiovasc Pharmacol , vol.21 , pp. 621-632
    • Kidwell, G.A.1    Gonzalez, M.D.2
  • 16
    • 0028203260 scopus 로고
    • Effects of MS-551, a new class III antiarrhythmic drug, on programmed stimulation-induced ventricular arrhythmias, electrophysiology, and hemodynamics in a canine myocardial infarction model
    • Kondoh K, Hashimoto H, Nishiyama H, Umemura K, Ozaki T, Uematsu T, Nakashima M (1994) Effects of MS-551, a new class III antiarrhythmic drug, on programmed stimulation-induced ventricular arrhythmias, electrophysiology, and hemodynamics in a canine myocardial infarction model. J Cardiovasc Pharmacol 23:674-680
    • (1994) J Cardiovasc Pharmacol , vol.23 , pp. 674-680
    • Kondoh, K.1    Hashimoto, H.2    Nishiyama, H.3    Umemura, K.4    Ozaki, T.5    Uematsu, T.6    Nakashima, M.7
  • 17
    • 0023134609 scopus 로고
    • Effect of flecainide acetate on prevention of electrical induction of ventricular tachycardia and occurrence of ischemic ventricular fibrillation during the early postmyocardial infarction period: Evaluation in a conscious canine model of sudden death
    • Kou WH, Nelson SD, Lynch JJ, Montgomery DG, DiCarlo L, Lucchesi BR (1987) Effect of flecainide acetate on prevention of electrical induction of ventricular tachycardia and occurrence of ischemic ventricular fibrillation during the early postmyocardial infarction period: evaluation in a conscious canine model of sudden death. J Am Coll Cardiol 9:359-365
    • (1987) J Am Coll Cardiol , vol.9 , pp. 359-365
    • Kou, W.H.1    Nelson, S.D.2    Lynch, J.J.3    Montgomery, D.G.4    DiCarlo, L.5    Lucchesi, B.R.6
  • 18
    • 0015740580 scopus 로고
    • Electrophysiological properties of canine Purkinje cells in one-day-old myocardial infarction
    • Lazzara R, El-Sherif N, Scherlag BJ (1973) Electrophysiological properties of canine Purkinje cells in one-day-old myocardial infarction. Circ Res 33:722-734
    • (1973) Circ Res , vol.33 , pp. 722-734
    • Lazzara, R.1    El-Sherif, N.2    Scherlag, B.J.3
  • 19
    • 0021875075 scopus 로고
    • An evaluation of automaticity and triggered activity in the canine heart one to four days after myocardial infarction
    • Le Marec H, Dangman KH, Danilo P Jr, Rosen MR (1985) An evaluation of automaticity and triggered activity in the canine heart one to four days after myocardial infarction. Circulation 71:1224-1236
    • (1985) Circulation , vol.71 , pp. 1224-1236
    • Le Marec, H.1    Dangman, K.H.2    Danilo Jr., P.3    Rosen, M.R.4
  • 20
    • 0022541357 scopus 로고
    • The effects of doxorubicin on ventricular tachycardia
    • Le Marec H, Spinelli W, Rosen MR (1986) The effects of doxorubicin on ventricular tachycardia. Circulation 74:881-889
    • (1986) Circulation , vol.74 , pp. 881-889
    • Le Marec, H.1    Spinelli, W.2    Rosen, M.R.3
  • 21
    • 0023236574 scopus 로고
    • Effects of flecainide acetate on ventricular tachyarrhythmia and fibrillation in dogs with recent myocardial infarction
    • Lynch JJ, DiCarlo LA, Montgomery DG, Lucchesi BR (1987) Effects of flecainide acetate on ventricular tachyarrhythmia and fibrillation in dogs with recent myocardial infarction. Pharmacology 35:181-193
    • (1987) Pharmacology , vol.35 , pp. 181-193
    • Lynch, J.J.1    DiCarlo, L.A.2    Montgomery, D.G.3    Lucchesi, B.R.4
  • 23
    • 0023932102 scopus 로고
    • Effects of class I drugs on reentrant ventricular tachycardia in a canine model of myocardial infarction: On their antiarrhythmic and proarrhythmic mechanisms
    • Miyazaki T, Ogawa S, Sakai T, Hosokawa M, Sakurai K, Nakamura Y (1988) Effects of class I drugs on reentrant ventricular tachycardia in a canine model of myocardial infarction: on their antiarrhythmic and proarrhythmic mechanisms. Jpn Circ J 52:254-261
    • (1988) Jpn Circ J , vol.52 , pp. 254-261
    • Miyazaki, T.1    Ogawa, S.2    Sakai, T.3    Hosokawa, M.4    Sakurai, K.5    Nakamura, Y.6
  • 24
    • 0027423559 scopus 로고
    • Effect of E-4031, a new class III antiarrhythmic drug, on reentrant ventricular arrhythmias in comparison with conventional class I drugs
    • Ogawa S, Mitamura H, Katoh H (1993) Effect of E-4031, a new class III antiarrhythmic drug, on reentrant ventricular arrhythmias in comparison with conventional class I drugs. Cardiovasc Drugs Ther 7 [Suppl 3]:621-626
    • (1993) Cardiovasc Drugs Ther , vol.7 , Issue.3 SUPPL. , pp. 621-626
    • Ogawa, S.1    Mitamura, H.2    Katoh, H.3
  • 25
    • 0028950724 scopus 로고
    • Reentrant arrhythmias in the subacute infarction period: The proarrhythmic effect of flecainide acetate on functional reentrant circuits
    • Restivo M, Yin H, Caref EB, Patel AI, Ndrepepa G, Avitable MJ, Assadi MA, Isber N, El-Sherif N (1995) Reentrant arrhythmias in the subacute infarction period: the proarrhythmic effect of flecainide acetate on functional reentrant circuits. Circulation 91:1236-1246
    • (1995) Circulation , vol.91 , pp. 1236-1246
    • Restivo, M.1    Yin, H.2    Caref, E.B.3    Patel, A.I.4    Ndrepepa, G.5    Avitable, M.J.6    Assadi, M.A.7    Isber, N.8    El-Sherif, N.9
  • 26
    • 0001954570 scopus 로고    scopus 로고
    • Antiarrhythmic drugs
    • Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Goodman Gilman A (eds) McGraw-Hill, New York
    • Roden DM (1996) Antiarrhythmic drugs. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Goodman Gilman A (eds) Goodman and Gilman's the pharmacological basis of therapeutics, 9th edn. McGraw-Hill, New York, pp 839-874
    • (1996) Goodman and Gilman's the Pharmacological Basis of Therapeutics, 9th Edn. , pp. 839-874
    • Roden, D.M.1
  • 27
    • 0001862422 scopus 로고
    • Afterdepolarizations and triggered activity: Distinction from automaticity as an arrhythmogenic mechanism
    • Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE (eds) Raven Press, New York
    • Wit AL, Rosen MR (1992) Afterdepolarizations and triggered activity: distinction from automaticity as an arrhythmogenic mechanism. In: Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE (eds) The heart and cardiovascular system, 2nd edn. Raven Press, New York, pp 2113-2163
    • (1992) The Heart and Cardiovascular System, 2nd Edn. , pp. 2113-2163
    • Wit, A.L.1    Rosen, M.R.2
  • 28
    • 0027502217 scopus 로고
    • Effects of a new class I antiarrhythmic drug bidisomide on canine ventricular arrhythmia models
    • Wu ZJ, Awaji T, Hirasawa A, Motomura S, Hashimoto K (1993) Effects of a new class I antiarrhythmic drug bidisomide on canine ventricular arrhythmia models. Mol Cell Biochem 119:159-169
    • (1993) Mol Cell Biochem , vol.119 , pp. 159-169
    • Wu, Z.J.1    Awaji, T.2    Hirasawa, A.3    Motomura, S.4    Hashimoto, K.5
  • 29
    • 0029987125 scopus 로고    scopus 로고
    • Antiarrhythmic and proarrhythmic effects of sematilide in canine ventricular arrhythmia models
    • Xue YX, Eto K, Akie Y, Hashimoto K (1996) Antiarrhythmic and proarrhythmic effects of sematilide in canine ventricular arrhythmia models. Jpn J Pharmacol 70:129-138
    • (1996) Jpn J Pharmacol , vol.70 , pp. 129-138
    • Xue, Y.X.1    Eto, K.2    Akie, Y.3    Hashimoto, K.4
  • 30
    • 0031875948 scopus 로고    scopus 로고
    • Antiarrhythmic effects of a novel class III drug, KCB-328, on canine ventricular arrhythmia models
    • Xue Y, Tanabe S, Nabuchi Y, Hashimoto K (1998) Antiarrhythmic effects of a novel class III drug, KCB-328, on canine ventricular arrhythmia models. J Cardiovasc Pharmacol 32:239-247
    • (1998) J Cardiovasc Pharmacol , vol.32 , pp. 239-247
    • Xue, Y.1    Tanabe, S.2    Nabuchi, Y.3    Hashimoto, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.