On-line determination of reaction completion in a closed-loop hydrogenator using NIR spectroscopy

Applied Spectroscopy

Volumn 52, Issue 1, 1998, Pages 17-21

  Ward II, Howard W ^a   Sekulic, S Sonja ^a   Wheeler, Michael J ^b   Taber, Geraldine ^b   Urbanski, Frank J ^b   Sistare, Frank E ^b   Norris, Timothy ^a   Aldridge, Paul K ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b PFIZER INC   (United States)

Author keywords

Hydrogenation; Multivariate calibration; Near infrared; Near IR; NIR; Pharmaceutical; PLS

Indexed keywords

CATALYSTS; CHEMICAL REACTORS; DRUG PRODUCTS; GAS CHROMATOGRAPHY; INFRARED SPECTROSCOPY; LEAST SQUARES APPROXIMATIONS; PALLADIUM; REACTION KINETICS; SOLVENTS;

CLOSED LOOP HYDROGENATOR; MULTIVARIATE CALIBRATION; NEAR INFRARED SPECTROSCOPY; PARTIAL LEAST SQUARE METHOD; TETRAHYDROFURAN;

HYDROGENATION;

EID: 0031699467     PISSN: 00037028     EISSN: None     Source Type: Journal    
DOI: 10.1366/0003702981942582     Document Type: Article

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