Gas bubbles and their influence on microorganisms

Applied Mechanics Reviews

Volumn 51, Issue 1, 1998, Pages 113-120

  Chalmers, Jeffrey J ^a  

^a Ohio State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITIVES; ANIMAL CELL CULTURE; BIOCHEMICAL OXYGEN DEMAND; MICROORGANISMS; OXYGEN; SOLUBILITY;

DAMAGE MECHANISM; OXYGENATION;

BUBBLES (IN FLUIDS);

EID: 0031699417     PISSN: 00036900     EISSN: None     Source Type: Journal    
DOI: 10.1115/1.3098986     Document Type: Article

References (46)

1. Augenstein D, Sinskey AJ, and Wang DIC (1971), Effect of shear on the death of two strains of mamalian tissue cells, Biotechnol Bioeng 13, 409-418.
2. Backer M, Metzger L, Slaber P, Nevitt K, and Boder G (1988), Large-scale production of monoclonal antibodies in suspension culture, Biotechnol Bioeng 32 993-1000.
3. Bailey J and Ollis D (1986), Biochemical Engineering Fundamentals, Me Graw Hill, New York, New York.
4. Bavarian F, Fan LS, and Chalmers JJ (1991), Microscopic visualization of insect cell-bubble interactions. I: Rising bubbles, air-medium interface, and the foam layer, Biotechnol Prog 7 140-150.
5. Blanchard DC and Syzdek LD (1972), Concentration of bacteria in jet drops from bursting bubbles, J Geophysical Res 77 5087-5099.
6. Boulton-Stone JM and Blake JR (1993), Gas-bubbles bursting at a free surface, J Fluid Mech 154 437-466.
7. Chalmers JJ and Bavarian F (1991), Microscopic visualization of insect cell-bubble interactions. II: The bubble film and bubble rupture, Biotechnol Prog 7 151-158.
8. Chattopadhyay D, Rathman JF, and Chalmers JJ (1995a), Protective effect of specific medium additives with respect to bubble rupture, Biotechnol Bioeng 45 473-480.
9. Chattopadhyay D, Rathman JF, and Chalmers JJ (1995b), Thermodynamic approach to explain cell adhesion to air-medium interfaces, Biotechnol Bioeng 48 649-658.
10. Dodge T and Hu W (1986), Growth of hybridoma cells under different agitation conditions, Biotechnol Letters 8 683-686.
11. Garcia-Briones MA and Chalmers JJ (1992), Cell-bubble interactions: Mechanisms of suspended cell damage, Ann NY Acad Sci 665 219-229.
12. Garcia-Briones MA, Brodkey RS, and Chalmers JJ (1994), Computer simulations of the rupture of a gas bubble at a gas-liquid interface and its implications in animal cell damage, Chem Eng Sci 49 2301-2320.
13. Handa A, Emery A, and Spier RE (1987), On the evaluation of gas-liquid interfacial effects on hybridoma viability in bubble column bioreactors, Develop Biol Standard 66 241 -252.
14. Handa-Corrigan A, Emety AN, and Spier RE (1989), Effect of gas-liquid interfaces on the growth of suspended mammalian cells: Mechanism of cell damage by bubbles. Enz Microb Technol 11 230-235.
15. Hink WF and Strauss E (1979), Suspension culture of the Cabbage Looper (TN-368) cell line, Tissue Cult Assoc Man 5 1023-1025.
16. Hulscher M and Onken U (1988), Influence of bovine serum albumin on the growth of hybridoma cells in air-lift loop reactors using serum free medium, Biotechnol Lett 10 689-694.
17. Jobses I, Martens D, and Tramper J (1990), Lethal effects during gas sparging in animal cell culture. Biotechnol Bioeng 10 801-814.
18. Kilbum DG and Webb F (1968), Cultivation of animal cells at controlled dissolved oxygen partial pressure, Biotechnol Bioeng 10 801-814.
19. Kunas KT and Papoutsakis ET (1990a), The protective effect of serum against hydrodynamic damage of hybridoma cells in agitated and surface-aerated bioreactors, J Biotechnol 15 57-70.
20. Kunas KT and Papoutsakis ET (1990b), Damage mechanism of suspended animal cells in agitated bioreactors with and without bubble entrain-ment, Biotechnol Bioeng 36 476- 483.
21. Lee G, Huard T, Kaminski M and Palsson B (1988), Effect of mechanical agitation on hybridoma cell growth, Biotechnol Letters 10 625-628.
22. Lin A and Miller W (1992), CHO cells responses to low oxygen: regulation of oxygen consumption and sensitization to oxygen stress, Biotechnol Bioeng 40 505-516.
23. MacIntyre F (1968), Bubbles: A boundary-layer “microtome” for micron thick samples of a liquid surface, J Phys Chem 72 589-592.
24. MacIntyre F (1972), Flow patterns in breaking bubbles, J Geophys Res 77 5211-5228.
25. Maiorella B, Inlow D, Shauger A, and Harano D (1988), Large-scale insect cell-culture for recombinant protein production, Bio/technol 6 1406-1410.
26. Martens DE, de Gooijer CD, Beuvery EC, and Tramper J (1992), Effect of serum on hybridoma viable cell density and production of monoclonal antibodies in CSTR's and on shear sensitivity in air-lift loop reactors, Biotechnol Bioeng 39 891-897.
27. Michaels JD, Peterson JF, Mclntire LV, and Papoutsakis EF (1991), Protection mechanisms of freely suspended animal cells (CRL 8018) from fluid-mechanical injury. Viscometric and biorector studies using serum, Pluronic F-68 and polyethylene glycol, Biotechnol Bioeng 38 169-180.
28. Michaels JD, Nowak JE, Mallik AK, Koczo K, Wasan DT, and Papoutsakis ET (1995a), Analysis of Cell-to-Bubble Attachment in Sparged Bioreactors in the Presence of Cell-Protecting Additives, Biotechnol Bioeng 47 407-419.
29. Michaels JD, Nowak JE, Mallik AK, Koczo K, Wasan DT, and Papoutsakis ET (1995b), Interfacial Properties of Cell Culture Media with Cell-Protecting Additives, Biotechnol Bioeng 47 420-430.
30. Miller W, Wilke C, and Blanch H (1987), Transient responses of hybridoma metabolism to changes in the oxygen supply rate in continuous culture, Bioprocess Eng. 3 103-111.
31. Mizrahi A (1984), Oxygen in human lymphoblastoid cell line cultures and effect of polymers in agitated and aerated cultures, Devel Biol Std 55 93-102.
32. Murhammer DW and Goochee CF (1988), Scaleup of insect cell cultures: protective effects of Pluronic F-68, Bio/technol 6 1411-1415.
33. Murhammer DW and Goochee CF (1990), Sparged animal cell bioreactors: mechanisms of cell damage and Pluronic F-68 protection, Biotechnol Prog 6 391-397.
34. Oh SKW, Nienow AW, Al-Rubeai M, and Emary AN (1989), Effect of agitation intensity with and without continuous sparging on the growth and antibody production of hybridoma cells, J Biotechnol 12 45-62.
35. Oiler A, Buser C, Tyo M, and Thilly W (1989), Growth of mammalian cells at high oxygen concentration, J Cell Science 94 263-274.
36. Orton D and Wang DIC (1991), Fluorescent visualization of cell death in bubble aerated bioreactors, Cell Culture Engineering III, Engineering Foundation, Feb 2-7.
37. Runyan W and Gyer R (1963), Growth of L cell suspensions on a Warbug apparatus, Proc Soc Biol Med 112 1027-1030.
38. Smith CG, Greenfield PF, and Randerson DH (1987), Technique for determining the shear sensitivity of mammalian cells in suspension culture, Biotechnol Tech 1 39-44.
39. Shuler ML and Kargi F (1992), Bioprocess Engineering, Prentice Hall, Englewood Cliffs, New Jersey.
40. Schurch U, Kramer H, Einsele A, Widmer F, and Eppenberger HM (1988), Experimental evaluation of laminar shear stress on the behavior of hybridoma mass cell culture, producing monclonel antibodies against mi-fondrial creatine kinase, J Biotechnol 22 245-270.
41. Swim H and Parker R (1960), Effect of Pluronic F-68 on growth of fibroblasts in suspension on rotary shakers, Proc Soc Biol Med 103 252-254.
42. Telling RC and Elsworth R (1965), Submerged culture of hamster kidney cells in a stainless steel vessel, Biotechnol Bioeng 7 417-434.
43. Tramper J, Williams J, and Joustra D (1986), Shear sensitivity of insect cells in suspension, Enzyme Microb Technol 8 33-36.
44. Tramper J, Smit JD, and Straatman J (1988), Bubble column design for growth of fragile insect cells, Bioprocess Eng 3 37-41.
45. Trinh K, Garcia-Briones MA, Hink FH, and Chalmers JJ (1994), Quantification of damage to suspended insect cells as a result of bubble rupture, Biotechnol Bioeng 43 37-45.
46. van Dissel J, Olievier K, Leigh P, and Van Further R (1986), Reaction vessel for the measurements of O2 consumption by small number of cells in suspension, J Immunol Meth 92 271 -280.