LOH at 16p13 is a novel chromosomal alteration detected in benign and malignant microdissected papillary neoplasms of the breast

Human Pathology

Volumn 29, Issue 10, 1998, Pages 1113-1118

  Lininger, Ruth A ^a   Park, Won Sang ^b   Man, Yan Gao ^b   Pham, Thu ^b   MacGrogan, Gaëtan ^b   Zhuang, Zhengping ^b   Tavassoli, Fatteneh A ^b  

^a ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^b NONE

Author keywords

Breast; Genetics; LOH; Neoplasms; Papillary

Indexed keywords

DNA; PROTEIN P53;

ARTICLE; BREAST CARCINOMA; CHROMOSOMAL LOCALIZATION; CHROMOSOME 16P; CONTROLLED STUDY; EPITHELIUM HYPERPLASIA; GENE MUTATION; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRADUCTAL CARCINOMA; MICROSATELLITE INSTABILITY; PAPILLARY CARCINOMA; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR GENE;

EID: 0031697968     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(98)90422-1     Document Type: Article

References (24)

1. Smith H, Lu Y, Deng G, et al: Molecular aspects of early stages of breast cancer progression. J Cell Biochem 17G:144-152, 1993
2. Tsuda H, Uei Y, Fukutomi T, et al: Different incidence of loss of heterozygosity on chromosome 16q between intraductal papilloma and intracystic papillary carcinoma of the breast. Jpn J Cancer Res 85:992-996, 1994
3. Tsuda H, Callen D, Fukutomi T, et al: Allele loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of difference in phenotype and extent of spread. Cancer Res 54:513-517, 1994
4. Tsuda H: Differential diagnosis of intracystic papillary tumors of the breast by examination of loss of heterozygosity on chromosome 16q. Jpn J Cancer Chemother 22:52-58, 1995 (suppl 1)
5. Lakhani S, Slack D, Hamoudi R, et al: Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations. Lab Invest 74:129-135, 1996
6. Tavassoli F: Papillary lesions, in Pathology of the Breast. Norwalk, CT, Appleton & Lange, 1992, pp 193-228
7. Zhuang Z, Berttheau P, Emmert-Buck M, et al: A new microdissection technique for archival DNA analysis of specific cell populations in lesions less than one millimeter. AmJ Pathol 146:620-625, 1995
8. Gyapay G, Morissette J, Vignal A, et al: The 1993-1994 Genethon human genetic linkage map. Nature Genet 7:246-249, 315, 1994
9. Peral B, Ward C, San Millan J, et al: Evidence of linkage disequilibrium in the Spanish polycystic kidney disease I population. Am J Hum Genet 54:899-908, 1994
10. Bjornsson J, Short M, Kwiatkowski D, et al: Tuberous sclerosis-associated renal cell carcinoma: Clinical, pathological, and genetic features. AmJ Pathol 149:1201-1208, 1996
11. European Chromosome 16 Tuberous Sclerosis Consortium: Identification and characterization of the tuberous sclerosis gene on chromosome 16. Cell 75:1305-1315, 1993
12. Shen Y, Kozman H, Thompson A, et al: A PCR-based genetic linkage map of human chromosome 16. Genomics 22:68-76, 1994
13. Gomez M: Tuberous Sclerosis. New York, NY, Raven Press, 1988
14. Povey S, Armour J, Farndon P, et al: Report on 3rd International Chromosome 9 Workshop. Ann Hum Genet 58:177-250, 1994
15. Gabow P: Autosomal dominant polycystic kidney disease. N EnglJ Med 329:332-342, 1993
16. Gabow P: Polycystic kidney disease: Clues to pathogenesis. Kidney Int 40:989-996, 1991
17. Peral B, San Millan J, Ong A, et al: Screening the 3′ region of the polycystic kidney disease 1 (PKD1) gene reveals six novel mutations. Am J Hum Genet 58:86-96, 1996
18. Reeders S, Breuning M, Davies K, et al: A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16. Nature 317:542-544, 1985
19. Tsuchiya H, Orimoto K, Kobayashi K, et al: Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (TSC2) gene product of the Eker rat model. Cancer Res 56:429-433, 1996
20. D'Agati V, Trudel M: Lectin characterization of cystogenesis in the SBM transgenic model of polycystic kidney disease. J Am Soc Nephrol 3:975-983, 1992
21. Avner E, Sweeney WJ, Nelson W: Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease. Proc Natl Acad Sci U S A 89:7447-7451, 1992
22. Qian F, Watnick TJ, Onuchic LF, et al: The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I. Cell 87:979-987, 1996
23. Mulley J, Sutherland G: Integrating maps of chromosome 16. Curr Opin Genet Dev 3:425-431, 1993
24. Whitmore S, Apostolou S, Lane S, et al: Isolation and characterization of transcribed sequences from a chromosome 16 hn-cDNA library and the physical mapping of genes and transcribed sequences using a high-resolution somatic cell panel of human chromosome 16. Genomics 20:169-175, 1994