Deregulated expression of the retinoid X receptor α prevents muscle differentiation in P19 embryonal carcinoma cells

Cell Growth and Differentiation

Volumn 9, Issue 9, 1998, Pages 713-722

  Pratt, M A Christine ^a   Crippen, Craig ^a   Hubbard, Keith ^a   Menard, Michel ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DIMETHYL SULFOXIDE; DNA FRAGMENT; MESSENGER RNA; RETINOID X RECEPTOR;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL LEVEL; EMBRYO; GENE EXPRESSION REGULATION; MESODERM; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERTANT;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARCINOMA, EMBRYONAL; CELL DEATH; CELL DIFFERENTIATION; CLONE CELLS; DIMETHYL SULFOXIDE; GENE EXPRESSION REGULATION, NEOPLASTIC; MUSCLES; MUTATION; PHENOTYPE; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA; MURINAE;

EID: 0031697761     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schutz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., and Evans, R. M. The nuclear receptor superfamily: the second decade. Cell, 83: 835-839, 1995.
2. Heyman, R. A., Mangelsdorf, D. J., Dyck, J. A., Stein, R. B., Eichele, G., Evans, R. M., and Thaller, C. 9-cis Retinoic acid is a high affinity ligand for the retinoid X receptor. Cell, 68: 397-406, 1992.
3. Levin, A. A., Sturzenbecker, L. J., Kazmer, S., Bosakawski, T., Huselton, C., Allenby, G., Speck, J., Krattzeisen, C., Rosenberger, M., Lovey, A., and Grippo, J. F. 9-cis Retinoic acid stereoisomer binds and activates the nuclear receptor RXRα. Nature (Lond.), 355: 359-361, 1992.
4. Mangelsdorf, D. J., Ong, E. S., Dyk, J. A., and Evans, R. M. Nuclear receptor that identifies a novel retinoic acid response pathway. Nature (Lond.), 345: 224-229, 1990.
5. Mangelsdorf, D. J., Borgmeyer, U., Heyman, R. A., Zhou, J. Y., Ong, E. S., Oro, A. E., Kakizuka, A., and Evans, R. M. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev., 6: 329-344, 1992.
6. Leid, M., Kastner, P., and Chambon, P. Multiplicity generates diversity in the retinoic acid signalling pathways. Trends Biochem. Sci., 17: 427-433, 1992.
7. Glass, C. K. Differential recognition of target genes by nuclear receptor monomers, dimers and heterodimers. Endocrinol. Rev., 15: 391-407, 1994.
8. Zhang, X., Hoffmann, B., Tran, P. B-V., Graupner, G., and Pfahl, M. Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors. Nature (Lond.), 355: 441-445, 1992.
9. 3 signalling. Nature (Lond.), 355: 446-449, 1992.
10. Leid, M., Kastner, P., Lyons, R., Nakshatri, H., Saunders, M., Zacharewski, T., Chen, J-Y., Staub, A., Garnier, J-M., Mader, S., and Chambon, P. Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell, 68: 377-395, 1992.
11. Lohnes, D. P., Kastner, P., Dierich, A., Mark, M., LeMeur, M., and Chambon, P. Function of retinoic acid receptor γ in the mouse. Cell, 73: 643-658, 1993.
12. Li, E., Sucov, H. M., Lee, K-F., Evans, R. M., and Jaenisch, R. Normal development and growth of mice carrying a targeted disruption of the α1 retinoic acid receptor. Proc. Natl. Acad. Sci. USA, 90: 1590-1594, 1993.
13. Lufkin, T., Lohnes, D., Mark, M., Dierich, P., Gorry, M-P., Gaub, M., LeMeur, M., and Chambon, P. High postnatal lethality and testis degeneration in retinoic acid receptor α mutant mice. Proc. Natl. Acad. Sci. USA, 90: 7225-7229, 1993.
14. Sucov, H. M., Dyson, E., Gumeringer, C. L., Price, J., Chien, K. R., and Evans, R. M. RXRα mutant mice establish a genetic basis for vitamin A signalling in heart morphogenesis. Genes Dev., 8: 1007-1018, 1994.
15. Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., LeMeur, M., Decimo, D., Vonesch, J-L, Dolle, P., and Chambon, P. Genetic analysis of RXRα developmental function: convergence of RXR and RAR signalling pathways in heart and eye morphogenesis. Cell, 78: 987-1003, 1994.
16. Downes, M., Mynett-Johnson, L., and Muscat, G. E. O. The retinoic acid and retinoid X receptors are differentially expressed during myoblast differentiation. Endocrinology, 134: 2658-2660, 1994.
17. McBurney, M. W., and Rogers, B. J. Isolation of male murine embryonal carcinoma cells and their chromosomal replication patterns. Dev. Biol., 89: 503-508, 1982.
18. McBurney, M. W., Jones-Villeneuve, E. M. W., Edwards, M., and Anderson, P. Controlled differentiation of teratocarcinoma cells in culture. Nature (Lond.), 299: 165-167, 1982.
19. Jones-Villeneuve, E. M. V., McBurney, M. W., Rogers, K. A., and Kalnins, V. I. J. Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J. Cell Biol., 94: 253-262, 1982.
20. Edwards, M. K. S., Harris, J. F., and McBurney, M. W. Induced muscle differentiation in an embryonal carcinoma cell line. Mol. Cell. Biol., 3: 2280-2286, 1983.
21. Pratt, M. A. C., Kralova, J., and McBurney, M. W. A dominant negative mutation in the α retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell. Mol. Cell. Biol., 10: 6445-6453, 1990.
22. Rudnicki, M. A., Jackowski, G., Saggin, L., and McBurney, M. W. Actin and myosin expression during development of cardiac muscle from cultured embryonal carcinoma cells. Dev. Biol., 138: 348-358, 1990.
23. Braun, T. G., Buschhausen-Denker, E., Bober, E., Tannich, E., and Arnold, H. H. A novel human muscle factor related to but distinct from myoD induces myogenic conversion in 10T2 fibroblasts. EMBO J., 8: 701-709, 1989.
24. Edmonson, D. G., and Olson, E. N. A gene with homology to the myc similarity region of MyoD is expressed during myogenesis and is sufficient to activate the muscle differentiation program. Genes Dev., 3: 628-640, 1989.
25. Wright, W. E., Sassoon, D. A., and Lin, V. K. Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD1. Cell, 56: 607-617, 1989.
26. Vasseur, M., Duprey, P., Brulet, P., and Jacob, F. One gene and one pseudogene for the cytokeratin endo A. Proc. Natl. Acad. Sci. USA, 82: 1155-1159, 1985.
27. Schulte-Merker, S., and Smith, J. C. Mesoderm formation in response to Brachyury requires FGF signalling. Curr. Biol., 5: 62-67, 1995.
28. Wilkinson, D. G., Bhatt, S., and Herrmann, B. G. Expression of the mouse T gene and its role in mesoderm formation. Nature (Lond.), 343: 650-659, 1990.
29. Herrmann, B. G., Labeit, S., Poustka, A., King, T. R., and Lehrach, H. Cloning of the T gene required in mesoderm formation in the mouse. Nature (Lond.), 343: 617-622, 1990.
30. Smith, J. C., Price, B. M., Green, J. B. A., Weigel, D., and Herrmann, B. G. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell, 7: 79-87, 1991.
31. Vidricaire, G., Jardine, K., and McBurney, M. W. Expression of the Brachyury gene during mesoderm development in differentiating embryonal carcinoma cell cultures. Development (Camb.), 120: 115-122, 1994.
32. Gaunt, S. J., Bloom, M., and De Robertis, E. M. Expression of the mouse goosecoid gene during mid-embryogenesis may mark mesenchymal cell lineages in the developing head, limbs and body wall. Development (Camb.), 117: 769-778, 1993.
33. Benezra, R., Davis, R. L., Lockshon, D., Turner, D. L., and Weintraub, H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell, 61: 49-59, 1990.
34. Schmidt-Kastner, P. K., Jardine, K., Cormier, M., and McBurney, M. W. Genes transfected into embryonal carcinoma stem cells are both lost and inactivated at high frequency. Somat. Cell Mol. Genet., 22: 383-392, 1996.
35. Dollè, P., Fraulob, V., Kastner, P., and Chambon, P. Developmental expression of murine retinoid X receptor (RXR) genes. Mech. Dev., 45: 91-104, 1994.
36. Mangelsdorf, D. J., Umesono, K., Kliewer, S. A., Borgmeyer, U., Ong, E. S., and Evans, R. M. A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR. Cell, 66: 555-561, 1991.
37. Salbert, G., Fanjul, A., Piedrafita, F. J., Lu, X. P., Kim, S-J., Tran, P., and Pfahl, M. Retinoic acid receptors and retinoid X receptor-α down-regulate the transforming growth factor-β1 promoter by antagonizing AP-1 activity. Mol. Endocrinol., 7: 1347-1356, 1993.
38. Kamei, Y., Xu, L., Heinzel, T., Torchia, J., Kurokawa, R., Gloss, B., Lin, S-C., Heyman, R. A., Rose, D. W., Glass, C. K., and Rosenfeld, M. G. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell, 85: 403-414, 1996.
39. Zhang, X-k., Lehmann, J., Hoffmann, B., Dawson, M. I., Cameron, J., Graupner, G., Hermann, T., Tran, P., and Pfahl, M. Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature (Lond.), 358: 587-591, 1992.
40. Carnac, G., Albagli-Curiel, O., Levin, A., and Bonnieu, A. 9-cis Retinoic acid regulates the expression of the muscle determination gene Myf-5. Endocrinology, 133: 2171-2176, 1993.
41. Ruiz i Altaba, A., and Jessel, T. Retinoic acid modifies mesodermal patterning in early Xenopus embryos. Genes Dev., 5: 175-187, 1991.
42. Xiao, Y., Grieshammer, U., and Rosenthal, N. Regulation of a muscle-specific transgene by retinoic acid. J. Cell Biol., 129: 1345-1354, 1995.
43. Cunliffe, V., and Smith, J. C. Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. Nature (Lond.), 358: 427-430, 1992.
44. Srivastava, D., Cserjesi, P., and Olson, E. N. A subclass of bHLH proteins required for cardiac myogenesis. Science (Washington DC), 270: 1995-1999, 1995.
45. Lee, S., Christakos, S., and Small, M. B. Apoptosis and signal transduction: clues to a molecular mechanism. Curr. Opin. Cell Biol., 5: 286-291, 1993.
46. Chen, C., and Okayama, H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol., 7: 2745-2752, 1987.
47. Sucov, H. M., Murakami, K. K., and Evans, R. M. Characterization of an autoregulated response element in the mouse retinoic acid receptor type β gene. Proc. Natl. Acad. Sci. USA, 87: 5392-5396, 1990.
48. McBurney, M. W., Fournier, S., Jardine, K., and Sutherland, L. Intragenic regions of the murine Pgk-1 locus enhance integration of transfected DNAs into genomes of embryonal carcinoma cells. Somat. Cell Mol. Genet., 20: 515-528, 1994.
49. Affray, C., and Rougeon, F. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur. J. Biochem., 107: 303-314, 1980.
50. Solter, D., and Knowles, B. B. Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc. Natl. Acad. Sci. USA, 75: 5565-5569, 1978.