Distribution of ceftazidime in rat tissues

Biopharmaceutics and Drug Disposition

Volumn 19, Issue 7, 1998, Pages 473-478

  Granero, Luis ^a   Chesa Jiménez, Jesús ^a   Torres Molina, Francisca ^a   Péris, José Esteban ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Ceftazidime; Rats; Tissue distribution

Indexed keywords

CEFTAZIDIME; CEPHALOSPORIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; EXTRACELLULAR FLUID; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PARTITION COEFFICIENT; RAT; TISSUE DISTRIBUTION;

ANIMALS; CEFTAZIDIME; CEPHALOSPORINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXTRACELLULAR SPACE; HALF-LIFE; INFUSIONS, INTRAVENOUS; MALE; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 0031695928     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199810)19:7<473::AID-BDD125>3.0.CO;2-M     Document Type: Article

References (15)

1. L. Granero, M. Santiago, J. Cano, A. Machado and J.E. Peris, Analysis of ceftriaxone and ceftazidime distribution in cerebrospinal fluid and cerebral extracellular space in awake rats by in vivo microdialysis. Antimicrob. Agents Chemother., 39, 2728-2731 (1995).
2. F. Jehl, Ph. Birckel and H. Monteil, Hospital routine analysis of penicillins, third-generation cephalosporins and aztreonam by conventional and high-speed high-performance liquid chromatography. J. Chromatogr., 413, 109-119 (1987).
3. J.G. Wagner, Pharmacokinetic absorption plots from oral data alone or oral/intravenous data and an exact Loo-Riegelman equation. J Pharm. Sci., 72, 838-842 (1983).
4. M. Gibaldi and D. Perrier, Pharmacokinetics, Marcel Dekker, New York, 1982.
5. G. Lam, M. Chen and W.L. Chiou, Determination of tissue to blood partition coefficients in physiologically-based pharmacokinetic studies. J. Pharm. Sci., 71, 454-455 (1982).
6. R.N. Pierson, D.C. Price, J. Wang and R.K. Jain, Extracellular water measurements: organ tracer kinetics of bromide and sucrose in rats and man. Am. J. Physiol., 253, F254-F264 (1978).
7. A. Tsuji, T. Yoshikawa, K. Nishide, H. Minami, M. Kimura, E. Nakashima, T. Terasaki, E. Miyamoto, C.H. Nightingale and T. Yamana, Physiologically based pharmacokinetic model for β-lactam antibiotics I: Tissue distribution and elimination in rats. J. Pharm. Sci., 72, 1239-1252 (1983).
8. J.J. Schentag, Clinical significance of antibiotic tissue penetration. Clin. Pharmacokinet., 16(Suppl. 1), 25-31 (1989).
9. T.M. Barrat and M. Walser, Extracellular fluid in individual tissues and in whole animals: the distribution of radiosulfate and radiobromide. J. Clin. Invest., 48, 55-56 (1969).
10. G.B. Wallace and B.B. Brodie, The distribution of administered bromide in comparison with chloride and its relation to body fluids. J. Pharmacol. Exp. Ther., 65, 214-219 (1939).
11. D.M. Ryan, U. Mason and S.M. Harding, The penetration of ceftazidime into extravascular fluid, J. Antimicrob. Chemother., 8(Suppl. B), 283-288 (1981).
12. B. Hoffstedt and M. Walder, Penetration of ceftazidime into extracellular fluid in patients. J. Antimicrob. Chemother., 8(Suppl. B), 289-292 (1981).
13. D. Adam, B. Reichart and K.J. Williams, Penetration of ceftazidime into human tissue in patients undergoing cardiac surgery. J. Antimicrob. Chemother., 12(Suppl. A), 269-273 (1983).
14. K.B. Bischoff, R.L. Dedrick, D.S. Zaharko and J.A. Longstreth, Methotrexate pharmacokinetics. J. Pharm. Sci., 60, 1128-1133 (1971).
15. Y. Igari, Y. Sugiyama, S. Awazu and M. Hanano, Comparative physiologically based pharmacokinetics of hexobarbital, phenobarbital, and thiopental in the rat. J. Pharmacokinet. Biopharm., 10, 53-75 (1982)