Pharmacokinetic and metabolism studies using uniformly stable isotope labeled proteins with HPLC/CRIMS detection

Biopharmaceutics and Drug Disposition

Volumn 19, Issue 7, 1998, Pages 439-444

  Osborn, Blaire L ^a   Abramson, Fred P ^a  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Growth hormone; HPLC CRIMS; Isotope labeled proteins; Macromolecules

Indexed keywords

CARBON; GROWTH HORMONE; PROTEIN; SULFATE;

ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; COMPARTMENT MODEL; CONTROLLED STUDY; DATA ANALYSIS; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOASSAY; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; MASS SPECTROMETRY; NONHUMAN; OXIDATION; PROTEIN METABOLISM; RAT; TECHNIQUE;

ANIMALS; CARBON ISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMAN GROWTH HORMONE; ISOTOPE LABELING; MALE; MASS SPECTROMETRY; NITROGEN ISOTOPES; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031695608     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199810)19:7<439::AID-BDD124>3.0.CO;2-B     Document Type: Article

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