Ractopamine increases glucose turnover without affecting lipogenesis in the pig

Australian Journal of Agricultural Research

Volumn 49, Issue 7, 1998, Pages 1147-1152

  Dunshea, F R ^a   Leury, B J ^b   Tilbrook, A J ^c   King, R H ^a  

^a VIC INSTITUTE OF ANIMAL SCIENCE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Adipose tissue; agonist

Indexed keywords

EID: 0031693848     PISSN: 00049409     EISSN: None     Source Type: Journal    
DOI: 10.1071/A98001     Document Type: Article

References (28)

1. Adeola, O., McBride, B. W., and Young, L. G. (1992). Metabolic responses induced by isoproterenol in ractopamine-fed pigs. Journal of Nutrition 122, 1280-7.
2. Coutinho, L., Bergen, W., Merkel, R., and Smith, C. (1990). Quantitative characterization of the beta-adrenergic receptor subtype in porcine adipocytes. FASEB Journal 4, 650 (Abstract).
3. Dunshea, F. R., Eason, P. J., King, R. H., and Campbell, R. G. (1992a). Interrelations between gender, ractopamine and energy intake in finishing pigs. Proceedings of the Nutrition Society of Australia 17, 217.
4. Dunshea, F. R., Eason, P. J., King, R. H., and Campbell, R. G. (1993a). Effects of ractopamine, dietary energy and sex on protein and fat deposition in growing swine. Journal of Animal Science 71(Suppl. 1), 133 (Abstract).
5. Dunshea, F. R., Harris, D. M., Bauman, D. E., Boyd, R. D., and Bell, A. W. (1992b). Effect of porcine somatotropin on in vivo glucose kinetics and lipogenesis in the growing pig. Journal of Animal Science 70, 141-51.
6. Dunshea, F. R., and King, R. H. (1994). Temporal responses of plasma metabolites to ractopamine treatment in growing pigs. Australian journal of Agricultural Research 45, 1683-92.
7. Dunshea, F. R., and King, R. H. (1995). Responses to homeostatic signals in ractopamine-treated pigs. British Journal of Nutrition 73, 1-10.
8. Dunshea, F. R., King, R. H., and Campbell, R. G. (1993b). Interrelationships between dietary protein and ractopamine on protein and lipid deposition in finishing gilts. Journal of Animal Science 71, 2931-41.
9. Dunshea, F. R., King, R. H., Campbell, R. G., Sainz, R. D., and Kim, Y. S. (1993c). Interrelationships between sex and ractopamine on protein and lipid deposition in rapidly growing pigs. Journal of Animal Science 71, 2919-30.
10. Folch, J., Lees, M., and Stanley, G. H. S. (1957). A simple method for the isolation and purification of total lipides from animal tissues. Journal of Biological Chemistry 226, 497-509.
11. Freeman, C. P., Noakes, D. E., and Annison, E. F. (1970). The metabolism of glucose, acetate, palmitate, stearate and oleate in pigs. British Journal of Nutrition 24, 705-16.
12. Gopinath, R., and Etherton, T. D. (1989). Effects of porcine growth hormone on glucose metabolism of pigs: II. Glucose intolerance, peripheral tissue insulin sensitivity and glucose kinetics. Journal of Animal Science 67, 689-97.
13. Harris, D. M. (1995). Regulation of porcine adipose tissue lipogenesis by somatotropin. PhD Thesis, Cornell University.
14. Harris, D. M., Dunshea, F. R., Bauman, D. E., Boyd, R. D., Wang, S. Y., Johnson, P. A., and Clarke, S.D. (1993). Effect of in vivo somatotropin treatment of growing pigs on adipose tissue lipogenesis. Journal of Animal Science 71, 3293-300.
15. Honner, R. C., Dhillon, G. S., and Londos, C. (1985). cAMP-dependent protein kinase and lipolysis in rat adipoctyes. 1. Cell preparation, manipulation, and predictability in behaviour. Journal of Biology and Chemistry 260, 15122-9.
16. Liu, C. Y. and Mills, S. E. (1989). Determination of the affinity of ractopamine and clenbuterol for the beta-adrenoreceptor of the porcine adipocyte. Journal of Animal Science 67, 2937-42.
17. Liu, C. Y., Boyer, J. L., and Mills, S. E. (1989). Acute effects of beta-adrenergic agonists on porcine adipocyte metabolism in vitro. Journal of Animal Science 67, 2930-6.
18. Mersmann, H. J. (1987). Acute metabolic effects of adrenergic agents in swine. American Journal of Physiology 252, E85-E95.
19. Mills, S. E., Armentano, L. E., Russell, R. W., and Young, J. W. (1981) Rapid and specific isolation of radioactive biological samples. Journal of Dairy Science 64, 1719-23.
20. Mills, S. E., and Liu, C. Y. (1990). Sensitivity of lipolysis and lipogenesis to dibutytyl-cAMP and β-adrenergic agonists in swine adipocytes in vitro. Journal of Animal Science 68, 1017-23.
21. Mills, S. E., Liu, C. Y., Gu, Y., and Schinckel, A. P. (1990) Effects of ractopamine on adipose tissue metabolism and insulin binding in finishing hogs. Interaction with genotype and slaughter weight. Domestic Animal Endocrinology 7, 251-63.
22. Mitchell, A. D., Solomon, M. B., and Steele, N. C. (1990). Response of low and high protein select lines of pigs to the feeding of the beta-adrenergic agonist ractopamine (phenethanolamine). Journal of Animal Science 68, 3226-32.
23. Mitchell, A. D., Solomon, M. B., and Steele, N. C. (1991). Influence of level of dietary protein or energy on effects of ractopamine in finishing swine. Journal of Animal Science 69, 4487-95.
24. O'Hea, E. K., and Leveille, G. A. (1969). Significance of adipose tissue and liver as sites of fatty acid synthesis in the pig and the efficiency of utilization of various substrates for lipogenesis. Journal of Nutrition 99, 338-44.
25. Payne, R. W., Lane, P. W., and Genstat 5 Committee (1993). 'Genstat 5 Reference Manual.' (Oxford Science Publications: Oxford, UK.)
26. Peterla, T. A., and Scanes, C. G. (1990). Effects of β-adrenergic agonists on lipolysis and lipogenesis by porcine adipose tissue in vitro. Journal of Animal Science 68, 1024-9.
27. Takken, A., and Williams, K. C. (1981). A simplified procedure for long-term catheterisation of the anterior vena cava in adult pigs. Australian Veterinary Journal 57, 17-20.
28. Williams, A. C., Brunjes, P. M., Martin, R. J., Veehuizen, E. L., and Anderson, D. B. (1987). Influence of feeding ractopamine to finishing swine on the in vitro responsiveness of adipose tissue to ractopamine and insulin. Journal of Animal Science 65 (Suppl), 249 (Abstract).