Effect of sesamin on growth and arachidonic acid content of neoplastic and non-neoplastic prostate epithelial cell cultures

Phytotherapy Research

Volumn 12, Issue 6, 1998, Pages 417-421

  Griffiths, Gareth ^a   Jones, Helen E ^b   Eaton, Colby L ^c   Shimizu, Sakayu ^d   Stobart, A Keith ^e  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b Tenovus Cancer Research Centre   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d KYOTO UNIVERSITY   (Japan)

^e UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

5 desaturation; Prostatic epithelial cells; Sesamin

Indexed keywords

ARACHIDONIC ACID; LIGNAN DERIVATIVE; PROSTAGLANDIN; SESAME SEED OIL; SESAMIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARACHIDONIC ACID METABOLISM; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DOG; NONHUMAN; PROSTAGLANDIN SYNTHESIS INHIBITION; PROSTATE ADENOCARCINOMA; PROSTATE EPITHELIUM;

EID: 0031693110     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199809)12:6<417::AID-PTR334>3.0.CO;2-9     Document Type: Article

References (20)

1. Bligh, E. G., and Dyer, W. J. (1959). A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37, 911-917.
2. 2: a growth dependent response mediated by activation of heat shock transcription factor. Mol. Cell Biol. 12, 1528-1534.
3. Chaudry, A., McClinton, S., Moffat, L. E. F., and Wahle, K. W. J. (1991). Essential fatty acid distribution in the plasma and tissue phospholipids of patients with benign and malignant prostatic disease. Br. J. Cancer 64, 1157-1160.
4. Chaudry, A., Wahle, K.W. J., McClinton, S., and Moffat, L. E. F. (1994). Arachidonic acid metabolism in benign and malignant issue in vitro: effect of fatty acids and cyclooxygenase inhibitors. Int. J. Cancer 57, 176-180.
5. Dahiya, R., Boyle, B., Goldberg, B. C. et al. (1992). Metastasis-associated alterations in phospholipids and fatty acids of human prostatic adenocarcinoma cell lines. Biochem. Cell Biol. 70, 548-554.
6. Eaton, C. L., Hamilton, T. C., Kenvyn, K., and Pierrepoint, C. G. (1985). Studies of androgen and oestrogen binding in normal canine prostatic tissue and in epithelial and stromal cell lines derived from the canine prostate. Prostate 7, 377-388.
7. Eaton, C. L., and Pierrepoint, C. G. (1988). Growth of a spontaneous canine prostatic adenocarcinoma in vivo and in vitro: Isolation and characterization of a neoplastic prostatic epithelial cell line, CPA 1. Prostate 12, 129-143.
8. Fujiyamafujiwara, Y., Umedasawada, R., Kuzuyama, M., and Igarashi, O. (1995). Effects of sesamin on the fatty acid composition of the liver of rats fed n-6 and n-3 fatty acid rich diet. J. Nut Sci. Vitamin 41, 217-225.
9. Griffiths, G., Jones, H. E., Eaton, C. L., and Stobart, A. K. (1997). Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. Prostate 31, 29-36.
10. Hirata, F., Fujita, K., Ishikura, Y., Hosoda, K., Ishikawa, T., and Nakamura, H. (1996). Hypocholesterolemic effect of sesame lignan in humans. Atherosclerosis 122, 135-136.
11. Holbrooke, N. J., Planchon, P., Veber, N. et al. (1995). Evidence for separate mechanisms of anti-proliferative action of indomethacin and prostaglandin on MCF-7 breast cancer cells. Life Sci. 57, 1233-1240.
12. Horrobin, D. F. (1990). Essential fatty acids, lipid peroxidation and cancer. In, Omega-6 Essential Fatty Acids: Pathophysiology and Roles in Clinical Medicine, ed. by D.F. Horrobin, pp. 351-377, Wiley-Liss, New York.
13. Hubbard, N. E., Lim, D., Somers, S. D., and Erickson, K. L. (1993). Effects of in vitro exposure to arachidonic acid on TNF-alpha production by murine peritoneal macrophages. J. Leukocyte Biol. 54, 105-110.
14. Jareonkitmongkol, S., Kawashima, H., and Shimizu, S. (1993). Inhibitory effect of iignan compounds on the formation of arachidonic acid in a delta-5-desaturase-defective mutant of Mortierella alpina 1S-4. J. Ferm. Bioeng. 76, 406-407.
15. Jones, H. E., Harwood, J. L., Bowen, I. D., and Griffiths, G. (1992). Lipid composition of subcellular membranes from larvae and prepupae of Drosophila melanogaster. Lipids 27, 984-987.
16. MacRae, W. D., and Towers, G. H. N. (1984). Biological activities of lignans. Phytochemistry 23, 1027-1031.
17. Mimura, A., Takebayashi, K., Niwano, M., Takahara, Y., Osawa, T., and Tokuda, H. (1994). Antioxidative and anticancer components produced by cell culture of sesame. ACS Symposium Series 547, 281-294.
18. Ogawa, T., Makino, T., Hirose, N., and Sugano, M. (1994). Lack of influence of low blood cholesterol levels on pancreatic carcinogenesis after initiation with N-nitrosobis (2-oxopropyl)amine in Syrian Golden Hamsters. Carcinogenesis 15, 1663-1666.
19. Shimizu, S., Akimoto, K., Shinmen, Y., Kawashima, H., Sugano, M., and Yamada, H. (1991). Sesamin is a potent and specific inhibitor of Δ5 desaturase in polyunsaturated fatty acid biosynthesis. Lipids 26, 512-516.
20. Umedasawada, R., Fujiwara, Y., and Igarashi, O. (1994). Effect of sesamin on cholesterol synthesis and on the distribution of incorporated Iinoleic acid in lipid subfractions in cultured rat cells. Biosci. Biotech. Biochem. 58, 2114-2115.