DNA polymorphisms in the ACE gene, serum ACE activity and the risk of nephropathy in insulin-dependent diabetes mellitus

Nephrology Dialysis Transplantation

Volumn 13, Issue 10, 1998, Pages 2553-2558

  Freire, Maria Beatriz S ^a,d   Van Dijk, David J ^b,c   Erman, Arie ^b,c   Boner, Geoffrey ^b,c   Warram, James H ^a   Krolewski, Andrzej S ^a,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b RABIN MEDICAL CENTER   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

^d FACULDADE DE MEDICINA DE JUNDIAÍ   (Brazil)

^e Joslin Diabetes Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DNA POLYMORPHISM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEINURIA;

ALLELES; CASE-CONTROL STUDIES; CHILD; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; DNA; DNA PROBES; DNA TRANSPOSABLE ELEMENTS; FEMALE; GENE DELETION; GENOTYPE; HUMANS; MALE; PEPTIDYL-DIPEPTIDASE A; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 0031692515     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/13.10.2553     Document Type: Article

References (36)

1. Krolewski AS, Warram JH, Rand LI, Kahn CR. Epidemiologic approach to the etiology of type I diabetes mellitus and its complications. N Eng J Med 1987; 317: 1390-1398
2. Seaquist ER, Goetz FC, Rich S, Barbosa J. Familial clustering of diabetic kidney disease: evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med 1989; 320: 1161-1165
3. Borch-Johnsen K, Norgaard K, Hommel E, et al. Is diabetic nephropathy an inherited complication? Kidney Int 1992; 41: 719-722
4. Quinn M, Angelico MC, Warram JH, Krolewski AS. Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia 1996; 39: 940-945
5. Schmidt S, Ritz E. Genetics of the renin-angiotensin system and renal disease: a progress report. Curr Opin Neph Hypert 1997; 6: 146-51
6. Fogarty DG, Krolewski AS. Genetic susceptibility and the role of hypertension in diabetic nephropathy. Curr Opin Neph Hypert 1997; 6: 184-91
7. Liebermann J, Sastre A. Serum angiotensin-converting enzyme: Elevation in diabetes mellitus. Ann Int Med 1980; 93: 825-26
8. Hallab M, Berrut G, Bouhanick B, et al. Increase of activity of angiotensin-converting enzyme in insulin-dependent diabetic patients with permanent microalbuminuria. Arch Mal Coeur Vaiss 1992; 85: 1185-88
9. van Dijk DJ, Erman A, Erman T, Chen-Gal B, Sulkes J, Boner G. Increased serum angiotensin converting enzyme activity in type I insulin-dependent diabetes mellitus: its relation to metabolic control and diabetic complications. Eur J Clin Invest 1994; 24: 463-467
10. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin-I converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990; 86: 1343-1346
11. Marre M, Bernadet P, Gallois Y, et al. Relationship between angiotensin I converting enzyme gene polymorphism, plasma levels and diabetic retinal and renal complications. Diabetes 1994; 43: 384-388
12. Marre M, Jeunemaitre X, Gallois Y et al. Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulin-dependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group. J Clin Invest 1997; 99: 1585-1595
13. Lewis EJ, Hunsicker LG, Bain RP, Rohde RD, for the Collaborative Study Group. The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy. N Engl J Med 1993; 329: 1456-1462
14. Viberti GC, Mogensen CE, Groop LC, Pauls JF, for the European Microalbuminuria Captopril Study Group. Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. JAMA 1994; 271: 275-279
15. Ballerman BJ, Zeidel ML, Gunning ME, Brenner BM. Vasoactive peptides and the kidney. In: Brenner BM, Rector FC, ed. The Kidney. 4th ed. Saunders, Philadelphia: 1991: pp 510-583
16. Corvol P, Michaud A, Soubrier F, Williams TA. Recent advances in knowledge of the structure and function of the angiotensin I converting enzyme. J Hypert 1995; 13 [Suppl. 3]: S3-S10
17. Hubert C, Houot AM, Corvol P, Soubrier F. Structure of the angiotensin I converting enzyme gene. Two alternate promoters correspond to evolutionary steps of a duplicated gene. J Biol Chem 1991; 266: 15377-15383
18. Mattei MG, Hubert C, Alhenc-Gelas F, Roeckel N, Corvol P, Soubrier F. Angiotensin-I converting enzyme is on chromosome 17. (abstract) Cytogenet Cell Genet 1989; 51: 1041
19. Doria A, Warram JH, Rich SS, Krolewski AS. Determination of DNA haplotypes in unrelated individuals using denaturing gradient gel blots: angiotensin I converting enzyme locus. Hum Genet 1994; 94: 117-123
20. Villard E, Tiret L, Visvikis S, Rakotovao R, Cambien F, Soubrier F. Identification of new polymorphisms of the angiotensin I converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two QTL segregation-linkage analysis. Am J Hum Genet 1996; 56: 1268-1278
21. Cambien F, Poirier O, Lecerf L, et al. Deletion polymorphism in the gene for angiotensin-I converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-644
22. Ruiz J, Blanche H, Cohen N, et al. Insertion deletion polymorphism of the angiotensin converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA 1994; 91: 3662-3665
23. Dike Y, Hata A, Ogata Y, Numata Y, Shido K, Kondo K. Angiotensin converting enzyme as a genetic risk factor for coronary artery spasm. Implication in the pathogenesis of myocardial infarction. J Clin Invest 1995; 96: 2975-2979
24. Gardemann A, Weiss T, Schwarts O, et al. Gene polymorphism but not catalytic activity of angiotensin I converting enzyme is associated with coronary artery disease and myocardial infarction in low-risk patients. Circulation 1995; 92: 2796-2799
25. Lindpaintner K, Pfeffer MA, Kreutz R, et al. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 1995; 332: 706-711
26. Yoshida H, Mitarai T, Kawamura T, et al. Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy. J Clin Invest 1995; 96: 2162-2169
27. Hunley TE, Julian BA, Phillips III JA, et al. Angiotensin converting gene polymorphism: Potential silencer motif and impact on progression in IgA nephropathy. Kidney Int 1996; 49: 571-577
28. Schmidt S, Schone N, Ritz E and the diabetic nephropathy study group. Association of ACE gene polymorphisms and diabetic nephropathy? Kidney Int 1995; 17: 1176-1181
29. Tarnow L, Cambien F, Rossing P, et al. Lack of relationship between Insertion/Deletion polymorphism in the angiotensin-I converting enzyme gene and diabetic nephropathy and proliferative retinopathy in IDDM patients. Diabetes 1995; 44: 489-493
30. Doria A, Warram JH, Krolewski AS. Genetic predisposition to diabetic nephropathy: evidence for a role of angiotensin-I converting enzyme gene. Diabetes 1994; 43: 690-695
31. Kalter-Leibovici O, van Dijk DJ, Leibovici L et al. Risk factors for development of diabetic nephropathy and retinopathy in Jewish IDDM patients. Diabetes 1991; 40: 204-210
32. Erman A, Rabinov M, Rosenfeld J. Albumin determination in frozen urines-underestimated results. Clin Chim Acta 1998; 174: 255-261
33. Doria A, Warram JH, Krolewski AS. Molecular characterization of a DdeI melting polymorphism at the angiotensin I converting enzyme (ACE) locus. Hum Mut 1994; 4: 155-157
34. Rigat B, Hubert C, Corvol P. Soubrier F. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene. Nucleic Acids Res 1992; 20: 1433
35. Rothman KJ. Modern Epidemiology. Little, Brown & Company, Boston: 1986: pp 85 114
36. Villard E, Tiret L, Visvikis S, Rakotovao R, Cambien F. Soubrier F. Identification of new polymorphisms of the angiotensin I-converting enzyme (ACE) gene, a study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. Am J Hum Genet 1996; 58: 1268 78