Caffeine inhibits paresthesia induced by herpes simplex virus through action on primary sensory neurons in rats

Neuroscience Research

Volumn 31, Issue 3, 1998, Pages 235-240

  Shiraki, Kimiyasu ^a   Andoh, Tsugunobu ^a   Imakita, Masami ^b   Kurokawa, Masahiko ^a   Kuraishi, Yasushi ^a   Niimura, Michihito ^c   Kageyama, Seiji ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Acyclovir; Caffeine; Herpes simplex virus; Hypoalgesia; Paresthesia; Primary sensory neuron

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; CAFFEINE; CAFON; CENTRAL STIMULANT AGENT; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; HERPES; HERPES SIMPLEX VIRUS; HERPES SIMPLEX VIRUS 1; HYPOALGESIA; MALE; NERVE CELL; NONHUMAN; PARESTHESIA; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SPINAL GANGLION; TOPICAL DRUG ADMINISTRATION; VIRUS REPLICATION;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; BEHAVIOR, ANIMAL; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; GANGLIA, SENSORY; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNOHISTOCHEMISTRY; MALE; NEURONS, AFFERENT; NOCICEPTORS; PARESTHESIA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031692191     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(98)00050-9     Document Type: Article

References (30)

1. Andoh, T., Shiraki, K., Kurokawa, M., Kuraishi, Y., 1995. Paresthesia induced by cutaneous infection with herpes simplex virus in rats. Neurosci. Lett. 190, 101-104.
2. Blondeau, J.M., Aoki, F.Y., Nagy, J.I., 1993. Immunohistological characterisation of acute herpes simplex virus infection of lumbar dorsal root ganglia in the rat. J. Med. Microbiol. 38, 265-269.
3. Cook, K., Stevens, J.G., 1973. Pathogenesis of herpetic neuritis and gangionitis in mice: evidence of intra-axonal transport of infection. Infect. Immun. 7, 272-288.
4. Currie, K.P., Scott, R.H., 1992. Calcium-activated currents in cultured neurones from rat dorsal root ganglia. Br. J. Pharmacol. 106, 593-602.
5. Fredholm, B.B., 1995. Adenosine, adnosine receptors and the actions of caffeine. Pharmacol. Toxicol. 76, 93-101.
6. Gonzales, G.R., 1992. Post-herpes simplex type 1 neuralgia simulating post-herpetic neuralgia. J. Pain Sympt. Manag. 7, 320-323.
7. John, T.J., Mukundan, P., 1979. Virus inhibition by tea, caffeine and tannic acid. Indian J. Med. Res. 69, 542-545.
8. Karlsten, R., Gordh, T., Post, C., 1992. Local antinociceptive and hyperalgesic effects in the formalin test after peripheral administration of adenosine analogues in mice. Pharmacol. Toxicol. 70, 434-438.
9. Kimura, S., 1996. Reactivation of herpes simplex virus type 1 in cells of latently infected mouse trigeminal ganglia cultured in serum-free medium. Microbiol. Immunol. 40, 243-246.
10. Krohel, G.B., Richardson, J.R., Farrell, D.F., 1976. Herpes simplex neuropathy. Neurology 26, 596-597.
11. Kurokawa, M., Ochiai, H., Nagasaka, K., Neki, M., Xu, H., Kadota, S., Sutardjo, S., Matsumoto, T., Namba, T., Shiraki, K., 1993. Antiviral traditional medicines against herpes simplex virus (HSV-1) poliovirus, and measles virus in vitro and their therapeutic efficacies for HSV-1 infection in mice. Antiviral Res. 22, 175-188.
12. Laska, E.M., Sunshine, A., Zighelboim, I., Roure, C., Marrero, I., Wanderling, J., Olson, N., 1983. Effect of caffeine on acetaminophen analgesia. Clin. Pharmacol. Ther. 33, 498-509.
13. Layzer, R.B., Conant, M.A., 1974. Neuralgesia in recurrent herpes simplex. Neurology 31, 233-237.
14. Lund, K., Ziola, B., 1985. Cell sonicates used in the analysis of how measles and herpes simplex type 1 virus infections influence vero cell mitochondrial calcium uptake. Can. J. Biochem. Cell Biol. 63, 1194-1197.
15. McLean, J.H., Shipley, M.T., Bernstein, D.I., Corbett, D., 1993. Selective lesions of neural pathways following viral inoculation of the olfactory bulb. Exp. Neurol. 122, 209-222.
16. Misra, A.L., Pontani, R.B., Vadlamani, N.L., 1985. Potentiation of morphine analgesia by caffeine. Br. J. Pharmacol. 84, 789-791.
17. Neering, I.R., McBurney, R.N., 1984. Role for microsomal Ca storage in mammalian neurones? Nature 309, 158-160.
18. Pakzaban, P., Chiocca, E.A., 1994. Nerve growth factor protects against herpes simplex virus type 1 neurotoxicity in the rat striatum. Neuroreport 5, 993-996.
19. Penfold, M.E., Armati, P., Cunningham, A.L., 1994. Axonal transport of herpes simplex virions to epidermal cells: evidence for a specialized mode of virus transport and assembly. Proc. Natl. Acad. Sci. USA 91, 6529-6533.
20. Sawynok, J., Reid, A.R., 1996. Neurotoxin-induced lesions to central serotonergic, noradrenergic and dopaminergic systems modify caffeine-induced antinociception in the formalin tests and locomotor stimulation in rats. J. Pharmacol. Exp. Ther. 277, 646-653.
21. Sawynok, J., Yaksh, T.L., 1993. Caffeine as an analgesic adjuvant: a review of pharmacology and mechanisms of action. Pharmacol. Rev. 45, 43-85.
22. Sawynok, J., Reid, A.R., Doak, G.J., 1995. Caffeine antinociception in the rat hot-plate and formalin tests and locomotor stimulation involvement of noradrenergic mechanisms. Pain 61, 203-213.
23. Selmanowitz, V.J., 1971. Neurocutaneous herpes simplex. Int. J. Dermatol. 10, 227-232.
24. Shiraki, K., Rapp, F., 1988. Effect of caffeine on herpes simplex virus. Intervirology 29, 235-240.
25. 2+ signal termination in adult mouse DRG neurones. Neuroreport 5, 2073-2076.
26. Tanaka, S., Koike, T., 1992. Caffeine promotes survival of cultured sympathetic neurons deprived of nerve growth factor through a cAMP-dependent mechanism. Biochim. Biophys. Acta. 1175, 114-122.
27. White, C.L. III, Taxy, J.B., 1982. Early morphologic diagnosis of herpes simplex virus encephalitis: advantage of electron microscopy and immunoperoxidase staining. Hum. Pathol. 14, 135-139.
28. Yamamura, J., Koyasu, M., Sato, H., Kurokawa, M., Yoshida, Y., Amahabu, Y., Shiraki, K., 1996. Topical treatment of cutaneous herpes simplex virus-1 infection in mice with a specially formulated caffeine gel (Cafon). J. Dermatol. Sci. 12, 50-55.
29. Yamazaki, Z., Tagaya, I., 1980. Antiviral effects of atropine and caffeine. J. Gen. Virol. 50, 429-431.
30. Zimmermann, M., 1983. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16, 109-110.