Estimation of the effects of prednisolone on bone metabolism in rats by biochemical markers

Journal of Bone and Mineral Metabolism

Volumn 16, Issue 3, 1998, Pages 162-169

  Koyama, Shintaro ^a   Kushida, Kazuhiro ^a   Takahashi, Masaaki ^a   Kawana, Kouichi ^a   Hoshino, Hironobu ^a   Ishihara, Chiaki ^a   Inoue, Tetsuo ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone mineral density; Osteocalcin; Osteoporosis; Pyridinoline; Steroid

Indexed keywords

BIOCHEMICAL MARKER; OSTEOCALCIN; PREDNISOLONE; PYRIDINOLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE MASS; BONE METABOLISM; BONE MINERAL; BONE TURNOVER; CONTROLLED STUDY; CROSS LINKING; DRUG EFFECT; DRUG POTENCY; DUAL ENERGY X RAY ABSORPTIOMETRY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031691939     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007740050041     Document Type: Article

References (52)

1. Adinoff AD, Hollister JR (1983) Steroid-induced fractures and bone loss in patients with asthma. N Engl J Med 309:265-268
2. Ruegsegger P, Medici TC, Anliker M (1983) Corticosteroid-induced bone loss. A longitudinal study of alternate day therapy in patients with bronchial asthma using quantitative computed tomography. Eur J Clin Pharmacol 25:615-620
3. Gennari C (1985) Glucocorticoids and bone. In: Peck WA (eds) Bone and mineral research, vol 13. Elsevier, Amsterdam, pp 213-232
4. Fucik RF, Kukreja SC, Hargis GK, Bowser EN, Henderson WJ, Williams GA (1975) Effect of glucocorticoids on function of the parathyroid glands in man. J Clin Endocrinol Metab 40:152-155
5. Lukert BP, Adams JS (1976) Calcium and phosphorus homeostatis in man. Effect of corticosteroids. Arch Intern Med 136:1249-1253
6. Hahn TJ, Halstead LR, Teitelbaum SL, Hahn BH (1979) Altered mineral metabolism in glucocorticoid-induced osteopenia. Effect of 25-hydroxyvitamin D administration. J Clin Invest 64:655-665
7. Jowsey J, Riggs BL (1970) Bone formation in hypercortisonism. Acta Endocrinol 63:21-28
8. Meunier PJ, Dempster DW, Edonard C, Chapuy MC, Arlot M, Charhon S (1984) Bone histomorphometry in corticosteroidinduced osteoporosis in Cushing's syndrome. Adv Exp Med Biol 171:197-200
9. Caniggia A, Nuti R, Lore F, Vattimo A (1981) Pathophysiology of the adverse effects of glucoactive corticosteroids on calcium metabolism in man. J Steroid Biochem 15:153-161
10. 47Ca kinetics in normal subjects. Acta Endocrinol 61:173-192
11. Dietrich JW, Canalis EM, Maina DM, Raisz LG (1979) Effects of glucocorticoids on fetal rat bone collagen synthesis in vitro. Endocrinology 104:715-721
12. 3H]tetracycline. Calcif Tissue Res 20:275-290
13. 3H] tetracycline excretion from prelabeled. J Bone Miner Res 3:621-627
14. Goulding A, Gold E (1988) Effects of chronic prednisolone treatment on bone resorption and bone composition in intact and ovariectomized rats and in ovariectomized rats receiving β-estradiol. Endocrinology 122:482-487
15. Colwell A, Eastell R, Assiri AMA, Russel RGG (1990) Effect of diet on deoxypyridinoline excretion. In: Christiansen C, Overgaard K (eds) Osteoporosis. Osteoporosis Aps, Copenhagen, pp 590-591
16. Eastell R, Hampton L, Colwell A, Green JR, Assiri AMA, Hesp R, Russel RGG, Reeve J (1990) Urinary collagen crosslinks are highly correlated with radioisotopic measurements of bone resorption. In: Christiansen C, Overgaard K (eds) Osteoporosis. Osteoporosis Aps, Copenhagen, pp 469-470
17. Bressort C, Meunier PJ, Chapuy MC, Lejeune E, Edourd C, Darby AJ (1979) Histomorphometric profile, pathophysiology and reversibility of corticosteroid-induced osteoporosis. Metab Bone Dis Relat Res 1:303-319
18. Delmas PD, Schlemmer A, Gineyts E, Riis B, Christiansen C (1991) Urinary excretion of pyridinoline crosslinks correlates with bone turnover measured on iliac crest biopsy in patients with vertebral osteoporosis. J Bone Miner Res 6:639-644
19. Ohishi T, Kushida K, Takahashi M, Kawana K, Yagi K, Kawakami K, Horiuchi K, Inoue T (1994) Urinary bone resorption markers in patients with metabolic bone disorders. Bone (NY) 15:15-20
20. Brown JP, Delmas PD, Malaval L, Edouard C, Chapuy MC, Meunier PJ (1984) Serum bone Gla-protein: a specific marker for bone formation in postmenopausal osteoporosis. Lancet 1:1091-1093
21. Ismail F, Epstein S, Fallon MD, Thomas SB, Reinhardt TA (1988) Serum bone gla protein and the vitamin D endocrine system in the oophorectomized rat. Endocrinology 122:624-630
22. Griffin MG, Kimble R, Hopfer W, Pacifici R (1993) Dual-energy X-ray absorptiometry of the rat: accuracy, precision, and measurement of bone loss. J Bone Miner Res 8:795-800
23. Sievanen H, Kannus P, Jarvinen M (1994) Precision of measurement by dual energy X-ray absorptiometry of bone mineral density and content in rat hindlimb in vitro. J Bone Miner Res 9:473-478
24. Hosoda K, Eguchi H, Nakamoto T, Kubota T, Honda H, Jindai S, Hasegawa R, Kiyoki T, Shiraki M (1992) A sandwich immunoassay for human intact osteocalcin. Clin Chem 38:2233-2238
25. Takahashi M, Ohishi T, Aoshima H, Kushida K, Inoue T, Horiuchi K (1993) Pre-fractionation with cation exchanger for determination of intermolecular crosslinks, pyridinoline and pentosidine, in hydrolysate. J Liq Chromatogr 16:1355-1370
26. Kivirikko KI, Laitinen O, Prockop DI (1967) Modification of a specific assay for hydroxyproline in urine. Anal Biochem 19:249-255
27. 3. Clin Orthop 181:264-268
28. Jee WSS, Park HZ, Roberts WE, Kenner GH (1970) Corticosteroid and bone. Am J Anat 129:477-478
29. 3. Clin Orthop 181:264-268
30. Korkor A, Martin KJ, Olgaard K, Bergfeld M, Teitelbaum S, Slatopolsky E (1983) Altered adenosine 3′,5′-monophosphate release in response to parathyroid hormone by isolated perfused bone from glucocorticoid-treated dogs. Endocrinology 113:625-631
31. Jee WSS, Park HZ, Roberts WE, Kenner GH (1970) Corticosteroid and bone. Am J Anat 129:477-480
32. Shepard RM, Horst RL, Hamstra AJ, Deluca HF (1979) Determination of vitamin D and its metabolites in plasma from normal and anephric man. Biochem J 182:55-69
33. Hara K, Akiyama Y, Ohkawa I, Tajima T (1993) Effect of menatetrenone on prednisolone-induced bone loss in rats. Bone (NY) 14:813-818
34. Yamazaki I, Shino A, Shimizu Y, Tsukuda R, Shirakawa Y, Kinoshita M (1986) Effect of ipriflavone on glucocorticoid-induced osteoporosis on rats. Life Sci 38:951-958
35. Bressort C, Meunier PJ, Chapuy MC, Lejeune E, Edourd C, Darby AJ (1979) Histomorphometric profile, pathophysiology and reversibility of corticosteroid-induced osteoporosis. Metab Bone Dis Relat Res 1:303-319
36. Nordin BEC, Marshall DH, Francis RH, Crilly RG (1981) The effects of sex steroids and corticosteroid hormone on bone. J Steroid Biochem 15:171-174
37. Findling JM, Adams ND, Lemann J, Gray RW, Thomas CJ, Tyrrell JB (1982) Vitamin D metabolites had parathyroid hormone in Cushing's syndrome: relationship to calcium and phosphorus homeostasis. J Clin Endocrinol Metab 54:1039-1044
38. Suzuki Y, Ichikawa Y, Saito E, Homma M (1983) Importance of increased urinary calcium excretion in the development of secondary hyperparathyroidism of patients under glucocorticoid therapy. Metabolism 32:151-156
39. 3 modulates glucocorticoid-induced alteration in serum bone gla protein and bone histomorphometry. Endocrinology 120:531-536
40. Storey E (1963) The influence of adrenal cortical hormones on bone formation and resorption. Clin Orthop 30:197-217
41. Ali NJ, Capewell S, Ward MJ (1991) Bone turnover during high dose inhaled corticosteroid treatment. Thorax 46:160-164
42. Gennari C, Imbimbo B, Montagnani M, Bernini M, Nardi P, Avioli LV (1984) Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans. Calcif Tissue Int 36:245-252
43. Morrison D, Ali NJ, Routledge PA, Capewell S (1992) Bone turnover during short course prednisolone treatment in patients with chronic obstructive airway disease. Thorax 47:418-420
44. Lukert BP, Higgino JC, Stoskopf MM (1986) Serum osteocalcin is increased in patients with hyperthyroidism and decreased in patients receiving glucocorticoids. J Clin Endocrinol Metab 62: 1056-1058
45. Nielsen HK, Thomas K, Eriksen EF, Charles P, Storm T, Morsekilde L (1988) The effects of high dose glucocorticoid administration on serum bone gammacarboxyglutamic acid containing protein, serum alkaline phosphatase and vitamin D metabolites in normal subjects. Bone Miner 4:105-113
46. Reid IR, Chapman GE, Frasen TRC (1986) Low serum osteocalcin levels in glucocorticoid treated asthmatics. J Clin Endocrinol Metab 62:379-383
47. Baron R, Tross R, Vignery A (1984) Evidence of sequential remodeling in rat trabecular bone: morphology, dynamic histomorphometry, and changes during skeletal maturation. Anat Rec 208:137
48. Van Hoof VO, Hoylaerts MF, Geryl H (1990) Age and sex distribution of alkaline phosphatase isoenzymes by agarose electrophoresis. Clin Chem 36:875-878
49. Wong GL (1979) Basal activities and hormone responsiveness of osteoclast-like and osteoblast-like bone cells are regulated by glucocorticoids. J Biol Chem 254:6337-6340
50. Hahn TJ, Westbrook SL, Halstead LR (1984) Cortisol modulation of osteoblast metabolic activity in cultured neonatal rat bone. Endocrinology 114:1864-1870
51. Gundberg CM, Markowitz ME, Mizruchi M, Rosen JF (1985) Osteocalcin in human serum: a circadian rhythm. J Clin Endocrinol Metab 60:736-739
52. Storey E (1960) Bone changes associated with cortisone administration in the rat. Br J Exp Pathol 41:207-213