Granulocyte-macrophage colony-stimulating factor in patients with neutropenic fever is potent after low-risk but not after high-risk neutropenic chemotherapy regimens: Results of a randomized phase III trial

Journal of Clinical Oncology

Volumn 16, Issue 9, 1998, Pages 2930-2936

  Ravaud, Alain ^a   Chevreau, Christine ^b   Cany, Laurent ^b   Houyau, Philippe ^b   Dohollou, Nadine ^b   Roché, Henri ^b   Soubeyran, Pierre ^b   Bonichon, Françoise ^b   Mihura, Jeanne ^b   Eghbali, Houchinge ^b   Tabah, Isabelle ^b   Bui, Binh Nguyen ^b  

^a INSTITUT BERGONIÉ   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; BLEOMYCIN; CEFTRIAXONE; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUOROURACIL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IFOSFAMIDE; MITOMYCIN; NAVELBINE; PIPERACILLIN; PREDNISOLONE; VINCRISTINE; VINDESINE;

ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG INDICATION; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NEUTROPENIA; PRIORITY JOURNAL; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 0031690503     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.9.2930     Document Type: Article

References (17)

1. Bodey GP, Buckley M, Sathe YS, et al: Quantitative relationship between circulating leukocytes and infection in patients with acute leukemia. Ann Intern Med 64:328-340, 1966
2. Pizzo PA: Granulocytopenia and cancer therapy. Past problems, current solutions, future challenges. Cancer 54:328-334, 1984
3. Rolston KV, Berkey P, Bodey GP, et al: A comparison of imipenem to ceftazidime with or without amikacin as empiric therapy in febrile neutropenic patients. Arch Intern Med 152:283-291, 1992
4. Antman K, Griffin JD, Elias A, et al: Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression. N Engl J Med 319:593-598, 1988
5. De Vries, Biesma B, Willem PHB, et al: A double blind placebo controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma. Cancer Res 51:116-122, 1991
6. Crawford F, Ozer H, Stoller R, et al: Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer. N Engl J Med 325:164-170, 1991
7. Bui BN, Chevallier B, Chevreau C, et al: Efficacy of lenograstim on hematologic tolerance to MAID chemotherapy in patients with advanced soft tissue sarcoma and consequences on treatment dose-intensity. J Clin Oncol 13:2629-2636, 1995
8. American Society of Clinical Oncology: Recommendations for the use of hemato-poietic colony-stimulating factors: Evidence-based, clinical practice guidelines. J Clin Oncol 12:2471-2508, 1994
9. Update of recommendations for the use of hematopoietic colony- stimulating factors: Evidence-based clinical practice guidelines. J Clin Oncol 14:1957-1960, 1996
10. Blay JY, Fervers B, Latour JF, et al: Standards, options et recommandations pour l'utilisation des facteurs de croissance hématopoïétique en cancérologie. Bull Cancer 82:487s-508s, 1995 (suppl 4)
11. Miller AB, Hoogstraten B, Staguet M, et al: Reporting results of cancer treatment. Cancer 47:207-214, 1981
12. Maher DW, Lieschke GJ, Green M, et al: Filgrastim in patients with chemotherapy-induced febrile neutropenia. A double-blind placebo-controlled trial. Ann Intern Med 121:492-501, 1994
13. Mayordomo JI, Rivera F, Diaz-Puente MT, et al: Improving treatment of chemo-therapy-induced neutropenic fever by administration of colony-stimulating factors. J Natl Cancer Inst 87:803-808, 1995
14. Vellenga E, Uyl-de Groot CA, de Wit R, et al: Randomized placebo-controlled trial of granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related febrile neutropenia. J Clin Oncol 14:619-627, 1996
15. Biesma B, de Vries EGE, Willemse PHB, et al: Efficacy and tolerability of recombinant human granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related leukopenia and fever. Eur J Cancer 26:932-936, 1990
16. Bodey GP, Anaissie E, Gutterman J, et al: Role of granulocyte-macrophage colony-stimulating factor as adjuvant treatment in neutropenic patients with bacterial and fungal infection. Eur J Clin Microbiol Infect Dis 13:18-22, 1994 (suppl 2)
17. Pizzo PA: Management of fever in patients with cancer and treatment-induced neutropenia. N Engl J Med 328:1323-1332, 1993