Evidence for a second genetic locus in Carney complex

British Journal of Dermatology

Volumn 139, Issue 4, 1998, Pages 572-576

  Irvine, A D ^a   Armstrong, D K B ^a   Bingham, E A ^b   Hadden, D R ^b   Nevin, N C ^a   Hughes, A E ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL VICTORIA HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 2P; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE LOCUS; HEART MYXOMA; HUMAN; LENTIGINOSIS; MALE; MULTIPLE ENDOCRINE NEOPLASIA; PEDIGREE; PRIORITY JOURNAL;

BREAST NEOPLASMS; CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; CHROMOSOME MAPPING; DNA; FEMALE; HEART NEOPLASMS; HUMANS; LENTIGO; MULTIPLE ENDOCRINE NEOPLASIA; MYXOMA; PEDIGREE; SKIN NEOPLASMS; SYNDROME;

EID: 0031690215     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1998.02450.x     Document Type: Article

References (17)

1. Carney JA, Young WF. Primary pigmented nodular adrenocortical disease and its associated conditions. Endocrinologist 1992; 2: 6-21.
2. Carney JA, Headington JT, Su WPD. Cutaneous myxomas. A major component of the complex of myxomas, spotty pigmentation, and endocrine overactivity. Arch Dermatol 1986; 122: 790-8.
3. Carney JA, Toorkery BC. Myxoid fibroadenoma and allied conditions (myxomatosis) of the breast: a heritable disorder with special associations including cardiac and cutaneous myxomas. Am J Surg Pathol 1991; 15: 713-21.
4. McCarthy PM, Pichler JM, Schaff HV et al. The significance of multiple, recurrent, and 'complex' cardiac myxomas. J Thorac Cardiovasc Surg 1986; 91: 389-96.
5. Manthos CL, Sutherland RS, Sims JE et al. Carney's complex with hormone producing Sertoli cell tumor of the testicle. J Urol 1993; 150: 1511-12.
6. Yen RS, Allen BR, Ott R et al. The syndrome of right atrial myxoma, spotty skin pigmentation and acromegaly. Am Heart J 1992; 123: 243-4.
7. Utiger CA, Headington JT. Psammomatous melanotic schwannoma: a new cutaneous marker for Carney's complex. Arch Dermatol 1992; 129: 202-4.
8. Stratakis CA, Carney JA, Lin JP et al. Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2. J Clin Invest 1996; 97: 699-705.
9. Handley J, Carson D, Sloan J et al. Multiple lentigines, myxoid tumours and endocrine overactivity; four cases of Carney's complex. Br J Dermatol 1992; 126: 367-71.
10. Armstrong DKB, Irvine AD, Handley JM et al. Carney complex: report of a kindred with predominantly cutaneous manifestations. Br J Dermatol 1997; 136: 578-82.
11. Calender A, Schuffenecker I, Lenoir GM. The genetics of multiple endocrine neoplasia (MEN). Horm Res 1992; 38 (Suppl. 2): 16-23.
12. Mulligan LM, Eng C, Healey CS et al. Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC. Nat Genet 1994; 6: 70-4.
13. Eng C, Smith DP, Mulligan LM et al. Point mutation within the tyrosinase kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours. Hum Mol Genet 1994; 3: 237-41.
14. Grantz I, Yamada T, Tashiro Y et al. Mapping of the gene encoding the melanocortin-1 (alpha-melanocyte stimulating hormone) receptor (MC1R) to human chromosome 16q24.3. Genomics 1994; 19: 394-5.
15. Gantz I, Tashiro T, Barcroft C et al. Localization of the genes encoding the melanocortin-2 (adrenocorticotrophic hormone) and melanocortin-3 receptors to chromosomes 18p11.2 and 20q13.2-q13.3 by fluorescence in situ hybridization. Genomics 1993; 18: 166-7.
16. Lathrop GM, Lalouel JM, Julier C et al. Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci USA 1984; 81: 3443-6.
17. Murphy CM, Grau-Massanes M, Shanchez RL. Multiple cutaneous myxomas. Report of a case without other elements of Carney's complex. J Cutan Pathol 1995; 22: 556-62.