An efficient] large-scale synthesis of (R)-(-)-mevalonolactone using simple biological and chemical catalysts

Synthesis

Volumn , Issue 9, 1998, Pages 1259-1263

  Orru, Romano V A ^a   Osprian, Ingrid ^a   Kroutil, Wolfgang ^a   Faber, Kurt ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Chemoenzymatic synthesis; Enantioconvergent; Epoxide hydrolase; Mevalonolactone

Indexed keywords

MEVALONOLACTONE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; TECHNIQUE;

EID: 0031690074     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-6108     Document Type: Article

References (37)

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37. 3 hydrate is critical. The reaction was performed immediately after the reagent was received from Fluka.