Immunohistochemical demonstration of tissue transglutaminase in amyloid plaques

Acta Neuropathologica

Volumn 96, Issue 4, 1998, Pages 395-400

  Zhang, Wei ^a   Johnson, Brett R ^a   Suri, Dorothy E ^a   Martinez, Jose ^b   Bjornsson, Thorir D ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Amyloid peptide; Amyloid deposits; Protein polymerization; Tissue transglutaminase

Indexed keywords

AMINO ACID; AMYLOID BETA PROTEIN; DIMER; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN PRECURSOR;

AGED; ALZHEIMER DISEASE; ARTICLE; CASE REPORT; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IODINATION; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN POLYMERIZATION; SOLUBILITY; TISSUE DISTRIBUTION;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BRAIN; CEREBRAL CORTEX; FEMALE; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; POLYMERS; REFERENCE VALUES; SENILE PLAQUES; STAINING AND LABELING; TRANSGLUTAMINASES;

EID: 0031690048     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050910     Document Type: Article

References (40)

1. Aeschlimann D, Paulsson M (1994) Transglutaminases: protein cross-linking enzymes in tissues and body fluids. Thromb Haemost 71: 402-415
2. Ausubel FM, Brent R, Kingston RE, Moore DD, Smith JA, Seidman JG, Struhl K (1994) Immunohistochemical staining. In: Current protocols in molecular biology, vol 2. Wiley, New York, Sections 14.1.-2
3. Barrow CJ, Yasuda A, Kenny PTM, Zagorski MG (1992) Solution conformations and aggregational properties of synthetic amyloid β-peptides of Alzheimer's disease. J Mol Biol 225: 1075-1093
4. Bueé L, Ding W, Delacourte A, Fillit H (1993) Binding of secreted human neuroblastome proteoglycans to the Alzheimer's amyloid A4 peptide. Brain Res 601: 154-163
5. Campisi A, Renis M, Russo A, Sorrenti V, Di Giacomo C, Castroina C, Vanella A (1992) Transglutaminase activity in primary and subcultured rat astroglial cells. Neurochem Res 17: 1201-1205
6. Castano EM, Ghiso J, Prelli F, Gorevic PD, Migheli A, Frangione B (1986) In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease beta-peptide. Biochem Biophys Res Commun 141: 782-789
7. Dudek SM, Johnson GVW (1993) Transglutaminase catalyzes the formation of sodium dodecyl sulfate-insoluble, Alz-50-reactive polymers of τ. J Neurochem 61: 1159-1162
8. Dudek SM, Johnson GV (1994) Transglutaminase facilitates the formation of polymers of the beta-amyloid peptide. Brain Res 651: 129-133
9. Folk JE (1980) Transglutaminases. Annu Rev Biochem 49: 517-531
10. Fraser PE, Nguyen JT, Chin DT, Kirschner DA (1992) Effects of sulfate ions on Alzheimer β/A4 peptide assemblies: implications for amyloid fibril-proteoglycan interactions. J Neurochem 59: 1531-1540
11. Gentile V, Saydak M, Chiocca AE, Akande O, Birckbichler PJ, Lee NK, Stein JP, Davies PJA (1991) Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminase. J Biol Chem 266: 478-483
12. Gilad GM, Varon LE (1985) Transglutaminase activity in rat brain: characterization, distribution, and changes with age. J Neurochem 45: 1522-1526
13. Glenner GG, Wong CW (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120: 885-890
14. Grundke-Iqbal I, Iqbal K, Quinlan M, Tung Y-C, Zaidi M, Wisniewski H (1986) Microtubule-associated protein tau. A component of Alzheimer paired helical filament. J Biol Chem 61: 6084-6089
15. Hand D, Perry MJM, Haynes LW (1993) Cellular transglutaminases in neural development. Int J Dev Neurosci 11: 709-720
16. Hantgan RR, Francis CW, Scheraga HA, Marder VJ (1987) Fibrinogen structure and physiology. In: Colman RW, Hirsh J, Marder VJ, Salzman EW (eds) Hemostasis and thrombosis, basic principles and clinical practice, 2nd edn. Lippincott, Philadelphia, pp 269-288
17. Ho GJ, Gregory EJ, Smirnova IV, Zoubine MZ, Festoff BW (1994) Cross-linking of β-amyloid protein precursor catalyzed by tissue transglutaminase. FEBS Lett 349: 151-154
18. Ikura K, Takahata K, Sasaki R (1993) Cross-linking of a synthetic partial-length (1-28) peptide of the Alzheimer β/A4 amyloid protein by transglutaminase. FEBS Lett 326: 109-111
19. Iqbal K, Zaidi T, Thompson CH, Merz PA, Wisniewski HM (1984) Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition. Acta Neuropathol (Berl) 62: 167-177
20. Kang J, Lemaire H-G, Unterbeck A, Salbaum JM, Masters CL, Grzeschik K-H, Multhaup G, Beyreuther K, Muller-Hill B (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736
21. Kirschner DA, Abraham C, Selkoe DJ (1986) X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation. Proc Natl Acad Sci USA 83: 503-507
22. Korner G, Schneider DE, Purdon MA, Bjornsson TD (1989) Bovine aortic endothelial cell transglutaminase. Enzyme characterization and regulation of activity. Biochem J 262: 633-641
23. Kosik KS, Joachim CL, Selkoe DJ (1986) Microbubule-associated protein tau (τ) is a major antigenic component of paired helical filaments in Alzheimer disease. Proc Natl Acad Sci USA 83: 4044-4048
24. Lorand L, Conrad SM (1984) Transglutaminases. Mol Cell Biochem 58: 9-35
25. Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 82: 4245-4249
26. Masters CL, Multhaup G, Simms G, Pottgiesser J, Martins RN, Beyreuther K (1985) Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. EMBO J 4: 2757-2763
27. Merz PA, Wisniewski HM, Somerville RA, Bobin SA, Masters CL, Iqbal K (1983) Ulrastructural morphology of amyloid fibrils from neuritic and amyloid plaques. Acta Neuropathol (Berl) 60: 113-124
28. Miller DL, Papayannopoulos IA, Styles J, Bohin SA, Lin YY, Biemann K, Iqbal K (1993) Peptide composition of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease. Arch Biochem Biophys 301: 41-52
29. Pastuszko A, Wilson DF, Erecinska M (1986) A role for transglutaminase in neurotransmitter release by rat brain synaptosomes. J Neurochem 46: 499-508
30. Ponte P, Gonzalez-DeWhitt P, Schilling J, Miller J, Hsu D, Greenberg B, Davis K, Wallace W, Lieberburg I, Fuller F, Cordell B (1988) A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors. Nature 331: 525-527
31. 2 M receptor. FEBS Lett 338: 161-166
32. Roher AE, Lowenson JD, Clarke S, Wolkow C, Wang R, Cotter RJ, Reardon IM, Zurcher-Neely HA, Heinrikson RL, Ball MJ, Greenberg BD (1993) Structural alterations in the peptide backbone of β-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J Biol Chem 268: 3072-3083
33. Sanan DA, Weisgraber KH, Russell SJ, Mahley RW, Huang D, Saunders A, Schmechel D, Wisniewski T, Frangione B, Roses AD, Strittmatter WJ (1994) Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils. J Clin Invest 94: 860-869
34. Selkoe DJ, Abraham C, Ihara Y (1982) Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers. Proc Natl Acad Sci USA 79: 6070-6074
35. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olsen BJ, Klenk D (1985) Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85
36. Strittmatter WJ, Saunders AM, Schmechel D, Periack-Vance M, Enghild J, Salvesen GS, Roses AD (1993) Apolipoprotein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 90: 1977-1981
37. Tomski SJ, Murphy RM (1992) Kinetics of aggregation of synthetic β-amyloid peptide. Arch Biochem Biophys 294: 630-638
38. Wisniewski T, Ghiso J, Frangione B (1991) Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation. Biochem Biophys Res Commun 179: 1247-1254
39. Wong CW, Quaranta V, Glenner GG (1985) Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related. Proc Natl Acad Sci USA 82: 8729-8732
40. Zhang W, Johnson BR, Bjornsson TD (1996) Pharmacologic inhibition of transglutaminase-induced cross-linking of Alzheimer's amyloid β-peptide. Life Sci 60: 2323-2332