Clinical usefulness of a new chemiluminescent two-site immunoassay for human calcitonin

Experimental and Clinical Endocrinology and Diabetes

Volumn 106, Issue 4, 1998, Pages 353-359

  Grauer, A ^a,b   Raue, F ^a   Ziegler, R ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Inst for Endocrinol and Nucl Med   (Germany)

Author keywords

Calcitonin; Diagnosis; Immunoassay; Medullary thyroid carcinoma

Indexed keywords

CALCITONIN; PENTAGASTRIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CALCITONIN BLOOD LEVEL; CHEMOLUMINESCENCE; CLINICAL TRIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FOLLOW UP; HUMAN; HUMAN EXPERIMENT; IMMUNOASSAY; MALE; MEDICAL DECISION MAKING; NORMAL HUMAN; PRIORITY JOURNAL; SCHOOL CHILD; VEIN CATHETERIZATION;

EID: 0031690024     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0029-1211997     Document Type: Article

References (17)

1. Barbot N, Calmettes C, Schuffenecker I, Saint Andre JP, Franc B, Rohrner V, Jallet P, Bigorgne JC: Pentagastrin Stimulation test and early diagnosis of medullary thyroid carcinoma using an immunoradiometric assay of calcitonin: comparison with genetic screening in hereditary medullary thyroid carcinoma. J Clin Endocrinol Metab 78: 114-120, 1994
2. Body JJ, Heath H, III : Nonspecific increases in plasma immunoreactive calcitonin in healthy individuals: discrimination from medullary thyroid carcinoma by a new extraction technique. Clin Chem 30: 511-514, 1984
3. Eng C, Mulligan LM: Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and hirschsprung disease. Hum Mutat 9: 97-109, 1997
4. Frank-Raue K, Hoppner W, Frilling A, Kotzerke J, Dralle H, Haase R, Mann K, Seif F, Kirchner R, Rendl J, Deckart HF, Ritter MM, Hampel R, Klempa J, Scholz GH, Raue F: Mutations of the ret protooncogene in German multiple endocrine neoplasia families: relation between genotype and phenotype. German Medullary Thyroid Carcinoma Study Group. J Clin Endocrinol Metab 81: 3780-1783, 1996
5. Grauer A, Blind E: Tumor markers for the medullary thyroid carcinoma. Rec Prog Canc Res 125: 55-89, 1992.
6. Grauer A, Raue F: Diagnostic value of the peptides of calcitonin gene. In: Schmidt-Gayk, H.; Blind, E. Roth, H.-J. (eds). Calcium regulating hormones and markers of bone metabolism; measurement and interpretation, pp. 85-93, Clin Lab Publikations. Heidelberg, 1997
7. Horvit PK, Gagel RF: The goitrous patient with an elevated serum calcitonin-what to do? J Clin Endocrinol Metab 82: 335-337, 1997
8. Motte P, Vauzelle P, Gardet P, Ghillani P, Caillou B, Parmentier C, Bohuon C, Bellet D: Construction and clinical validation of a sensitive and specific assay for serum mature calcitonin using monoclonal anti-peptide antibodies. Clin Chim Acta 174: 35-54, 1988
9. Niccoli P, Wion Barbot N, Caron P, Henry JF, de Micco C, Saint A, J.P., Bigorgne JC, Modigliani E, Conte Devolx B: Interest of routine measurement of serum calcitonin: study in a large series of thyroidectomized patients. The French Medullary Study-Group. J Clin Endocrinol Metab 82: 338-341, 1997
10. Pacini F, Fontanelli M, Fugazzola L, Elisei R, Romei C, Di Coscio G, Miccoli P, Pinchera A: Routine measurement of serum calcitonin in nodular thyroid diseases allows the preoperative diagnosis of unsuspected sporadic medullary thyroid carcinoma [see comments]. J Clin Endocrinol Metab 78: 826-829, 1994
11. Perdrisot R, Bigorgne JC, Guilloteau D, Jallet P: Monoclonal immunoradiometric assay of calcitonin improves investigation of familial medullary thyroid carcinoma. Clin Chem 36: 381-383, 1990
12. Raue F, Frank-Raue K: Gehört die Calcitoninbstimmung zur Abklärung der Struma nodosa? Dt. Äprzteblatt 94: A-1067-1068, 1997
13. Rieu M, Lame MC, Richard A, Lissak B, Sambort B, Vuong Ngoc P, Berrod JL, Fombeur JP: Prevalence of sporadic medullary thyroid carcinoma: the importance of routine measurement of serum calcitonin in the diagnostic evaluation of thyroid nodules. Clin Endocrinol 42: 453-460, 1995
14. Seth R, Motté P, Kehely A, Wimalawansa SJ, Self CH, Bellet D, Bohuon C, MacIntyre I: A sensitive and specific two-site enzyme-immunoassay for human calcitonin using monoclonal antibodies. J Endocrinol 119: 351-357, 1988
15. Vierhapper H, Raber W, Bieglmayer C, Kaserer K, Weinhausl A, Niederle B: Routine measurement of plasma calcitonin in nodular thyroid diseases. J Clin Endocrinol Metab 82: 1589-1593, 1997
16. Wimalawansa SJ, Bailey F: Validation, role in perioperative assessment, and clinical applications of an immunoradiometric assay for human calcitonin. Peptides 16: 307-312, 1995
17. Zink A, Blind E, Raue F: Determination of serum calcitonin by immunometric 2-site assays in normal subjects and patients with medullary thyroid carcinoma. Eur J Clin Chem Clin Biochem 30: 831-835, 1992