Buprenorphine-related deaths among drug addicts in France: A report on 20 fatalities

Journal of Analytical Toxicology

Volumn 22, Issue 6, 1998, Pages 430-434

  Tracqui, A ^a   Kintz, P ^a   Ludes, B ^a  

^a INSTITUT DE MÉDECINE LÉGALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BUPRENORPHINE; DRUG METABOLITE; NORBUPRENORPHINE; PSYCHOTROPIC AGENT; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; DEATH; DRUG BLOOD LEVEL; DRUG DEPENDENCE; FATALITY; FEMALE; FLUORESCENCE POLARIZATION IMMUNOASSAY; FRANCE; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MALE; MASS SPECTROMETRY; RISK FACTOR; SUBLINGUAL DRUG ADMINISTRATION;

EID: 0031689387     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/22.6.430     Document Type: Article

References (36)

1. ®. Ann. Dermatol. Vénéréol. 123 (suppl. 1): S129-S130 (1996).
2. G. Decocq, D. Fremaux, A. Smail, M. Compagnon, and M. Andréjak. Complications locales après injection intraveineuse de comprimés dissous de buprénorphine. Presse Méd. 26: 1433 (1997).
3. L. Gourarier, W. Lowenstein, M. Gisselbrecht, J.M. Chauveau, C. Haas, and H. Durand. Syndrome de manque chez deux toxicomanes après injection intraveineuse de buprénorphine? Presse Méd 25:1239-1240 (1996).
4. A. Tracqui, P. Kintz, and P. Mangin. HPLC/MS determination of buprenorphine and norbuprenorphine in biological fluids and hair samples. J. Forensic Sci. 42: 111-114 (1997).
5. F. Facy and M. Verron. Drug abuse in France: a review of statistical data. Drug Alcohol Depend. 24: 1-9 (1989).
6. R.E.S. Bullingham, H.J. McQuay, E.J.B. Porter, M.C. Allen, and R.A. Moore. Sublingual buprenorphine used postoperatively: ten hour plasma drug concentration analysis. Br. J. Clin. Pharmacol. 13: 665-673 (1982).
7. J.J. Kuhlman, Jr., S. Lalani, J. Magluilo, Jr., B. Levine, W.D. Darwin, R.E. Johnson, and E.J. Cone. Human pharmacokinetics of intravenous, sublingual, and buccal buprenorphine. J. Anal. Toxicol. 20: 369-378 (1996).
8. S.L. Walsh, K.L. Preston, M.L. Stitzer, E.J. Cone, and C.E. Bigelow. Clinical pharmacology of buprenorphine: ceiling effects at high doses. Clin. Pharmacol. Ther. 55: 569-580 (1994).
9. H. Adriansen, B. Mattelaer, and H. Vanmeenen. A long-term open, clinical and pharmacokinetic assessment of sublingual buprenorphine in patients suffering from chronic pain. Acta Anaesthesiol. Belg. 36:33-40 (1985).
10. R.E.S. Bullingham, H.J. McQuay, A. Moore, and M.R.D. Bennett. Buprenorphine kinetics. Clin. Pharmacol. Ther. 28: 667-672 (1980).
11. K.A. Lehmann, U. Reichling, and R. Wirtz. Influence of naloxone on the postoperative analgesic and respiratory effects of buprenorphine. Eur. J. Clin. Pharmacol. 34: 343-352 (1988).
12. H.J. McQuay, R.E.S. Bullingham, M.R.D. Bennett, and R.A. Moore. Delayed respiratory depression. A case report and a new hypothesis. Acta Anaesthesiol. Belg. 30 (suppl.): 245-247 (1979).
13. S.E. Thörn, N. Rawal, and M. Wennhager. Prolonged respiratory depression caused by sublingual buprenorphine. Lancet i: 179-180 (1988).
14. R.C. Heel, R.N. Brogden, T.M. Speight, and G.S. Avery. Buprenorphine: a review of its pharmacological properties and therapeutic efficacy. Drugs 17: 81-110 (1979).
15. R.B. Pontani, N.L. Vadlamani, and A.L. Misra. Disposition in the rat of buprenorphine administered parenterally and as a subcutaneous implant. Xenobiotica 15: 287-297 (1985).
16. J.J. Kuhlman, Jr., J. Magluilo, Jr., E.J. Cone, and B. Levine. Simultaneous assay of buprenorphine and norbuprenorphine by negative chemical ionization tandem mass spectrometry. J. Anal. Toxicol. 20: 229-235 (1996).
17. R.C. Baselt and R.H. Cravey. Disposition of Toxic Drugs and Chemicals in Man, 4th ed. Chemical Toxicology Institute, Foster City, CA, 1995, pp 93-94.
18. D. Brewster, M.J. Humphrey, and M.A. McLeavy. Biliary excretion, metabolism and enterohepatic circulation of buprenorphine. Xenobiotica 11: 189-196 (1981).
19. D.E. Moody, J.D. Laycock, A.C. Spanbauer, D.J. Crouch, R.L. Foltz, J.L. Josephs, L. Amass, and W.K. Bickel. Determination of buprenorphine in human plasma by gas chromatography-positive ion chemical ionization mass spectrometry and liquid chromatography-tandem mass spectrometry. J. Anal. Toxicol. 21: 406-414 (1997).
20. B. Adelhøj, O.U. Petring, M. Ibsen, J. Brynnum, and H.E. Poulsen. Tardiv respirationsdepression efter intravenoøs buprenorfin - Et tilfælde hos en yngre rask mand. Ugeskr. Laeger 147: 1343 (1985).
21. M.H. Faroqui, M. Cole, and J. Curran. Buprenorphine, benzodiazepines and respiratory depression. Anaesthesia 38: 1002-1003 (1983).
22. A.L. Forrest. Buprenorphine and lorazepam. Anaesthesia 38: 598 (1983).
23. J.M. Gibbs, H.D. Johnson, and F.M. Davis. Patient administration of i.v. buprenorphine for postoperative pain relief using the 'Cardiff' demand analgesia apparatus. Br. J. Anaesth. 54: 279-284 (1982).
24. P.N. Jain and S.C. Shah. Respiratory depression following combination of epidural buprenorphine and intramuscular ketorolac. Anaesthesia 48: 898-899 (1993).
25. B. Kay. Buprenorphine, benzodiazepines and respiratory depression. Anaesthesia 39:491-492 (1984).
26. J.T.A. Knape. Early respiratory depression resistant to naloxone following epidural buprenorphine. Anesthesiology 64: 382-384 (1986).
27. C. Martegani, V. Varesio, and I. Agosta. Segnalazione di un caso di depressione respiratoria riferibile all'impiego di buprenorfina per via peridurale. Minerva Anestesiol. 53: 141-143 (1987).
28. D.P. Papworth. High dose buprenorphine for postoperative analgesia. Anaesthesia 38: 163 (1983).
29. J.F. Schmidt, B. Chræmmer-Jørgensen, J.E. Pedersen, and A. Risbo. Postoperative pain relief with naloxone. Severe respiratory depression and pain after high dose buprenorphine. Anaesthesia 40: 583-586 (1985).
30. S. Tixier-Wulff and C. Jourdan. Insuffisance respiratoire aiguë tardive après injection de buprénorphine. Ann. Fr. Anest. Réanim. 11: 240-241 (1992).
31. K.L. Preston, R.R. Griffiths, M.L. Stitzer, C.E. Bigelow, and I.A. Liebson. Diazepam and methadone interactions in methadone maintenance. Clin. Pharmacol. Ther. 36: 534-541 (1984).
32. D. Touzeau and L. Gourarier. Benzodiazépines et méthadone: liaison dangereuse? Ann. Méd. Int. 145 (suppl. 3): 19-22 (1994).
33. J.W. Downing, N.M. Goodwin, and J. Hicks. The respiratory depressive effects of intravenous buprenorphine in patients in an intensive care unit. S. Afr. Med. J. 55: 1023-1027 (1979).
34. P.J.Q. Watson, H.J. McQuay, R.E.S. Bullingham, M.C. Allen, and R.A. Moore. Single-dose comparison of buprenorphine 0.3 and 0.6 mg i.v. given after operation: clinical effects and plasma concentrations. Br. J. Anaesth. 54: 37-43 (1982).
35. F. Molke Jensen, N.H. Jensen, I.K. Holk, and M. Ravnborg. Prolonged and biphasic respiratory depression following epidural buprenorphine. Anaesthesia 42:470-475 (1987).
36. P.J. Cook, I.M. James, K.E.F. Hobbs, and D.R.C. Browne. Controlled comparison of i.m. morphine and buprenorphine for analgesia after abdominal surgery. Br. J. Anaesth. 54: 285-290 (1982).