Alcohol and host defense against pulmonary infection with Pneumocystis carinii

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 5 SUPPL., 1998, Pages

  Shellito, Judd E ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL CONSUMPTION; ALCOHOLISM; CONFERENCE PAPER; HOST RESISTANCE; HUMAN; INFECTION RISK; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL;

PNEUMOCYSTIS CARINII;

EID: 0031689013     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1998.tb04003.x     Document Type: Conference Paper

References (40)

1. Masur H, Michelis M, Greene J, et al: An outbreak of community-acquired Pneumocystis carinii pneumonia: Initial manifestation of cellular immune dysfunction. N Engl J Med 305:1431-1438, 1981
2. Gottlieb M, Schroff R, Schanker H, et al: Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: Evidence of a new acquired cellular immunodeficiency. N Engl J Med 305:1425-1431, 1981
3. Wallace JM HN, Lavange L, Glassroth J, Browdy BL, Rosen MJ, Kvale PA, Mangura BT, Reichman LB, Hopewell PC: Respiratory disease trends in the Pulmonary Complications of HIV Infection Study Cohort. Am J Respir Crit Care Med 155:72-80, 1997
4. Masur H, Lane H, Kovacs J, Allegra C, Edman J: Pneumocystis pneumonia: From bench to clinic. Ann Intern Med 111:813-826, 1989
5. Shellito J, Suzara V, Blumenfeld W, Beck J, Steger H, Ermak T: A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes. J Clin Invest 85:1686-1693, 1990
6. Beck J, Warnock M, Curtis J, et al: Inflammatory responses to Pneumocystis carinii in mice selectively depleted of helper T lymphocytes Am J Respir Cell Mol Biol 5:186-197, 1991
7. Harmsen A, Stankiewicz M: Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice. J Exp Med 172:937-945, 1990
8. Roths J, Sidman C: Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice. J Clin Invest 90:673-678, 1992
9. Chen W, Havell E, Harmsen A: Importance of endogenous tumor necrosis factor alpha and gamma Interferon in host resistance to Pneumocystis carinii infection. Infec Immun 60:1279-1284, 1992
10. Kolls J, Beck J, Nelson S, Summer W, Shellito J: Alveolar macrophage release of tumor necrosis factor during murine Pneumocystis carinii pneumonia. Am J Respir Cell Mol Biol 8:370-376, 1993
11. Ezekowitz R, Williams D, Koziel H, et al: Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor. Nature 351:155-158, 1991
12. Pottratz S, Martin WI: Mechanism of Pneumocystis carinii attachment to cultured rat alveolar macrophages. J Clin Invest 86:1678-1683, 1990
13. Williams M, Wright J, March K, Martin WI: Human surfactant protein A enhances attachment of Pneumocystis carinii to rat alveolar macrophages. Am J Respir Cell Mol Biol 14:232-238, 1996
14. Chadha K, Whitney R, Cummings M, Norman M, Windle M, Stadler I: Evaluation of interferon system among chronic alcoholics, in Seminara D, Watson R, Pawlowski A (eds): Alcohol, Immunomodulation, and AIDS. Progress in Clinical and Biological Research, vol 325. New York, Alan R. Liss, 1990, pp 123-133
15. Chadha K, Stadler I, Albini B, Nakeeb S, Thacore H: Effect of alcohol on spleen cells and their function in C57BL/6 mice. Alcohol 8:481-485, 1991
16. Thestrup-Pedersen K, Ladefoged K, Anderson P: Lymphocyte transformation test with liver specific protein and phytohemagglutinin in patients with liver disease. Clin Exp Immunol 24:1-8, 1976
17. Nelson S, Bagby G, Bainton B, Summer W: The effects of acute and chronic alcoholism on tumor necrosis factor and the inflammatory response. J Infect Dis 160:422-429, 1989
18. Nelson S, Bagby G, Summer W: Alcohol-induced suppression of tumor necrosis factor - A potential risk factor for secondary infection in the acquired immunodeficiency syndrome, in Seminara D, Watson R, Pawlowski A (eds): Alcohol, Immunomodulation, and AIDS. Progress in Clinical and Biological Research, vol 325. New York, Alan R. Liss, 1990, pp 211-220
19. D'Souza N, Mandujano J, Nelson S, Summer W, Shellito J: Alcohol ingestion impairs host defenses predisposing otherwise healthy mice to Pneumocystis carinii infection. Alcohol Clin Exp Res 19:1219-1225, 1995
20. Shellito J, Olariu R: Alcohol decreases T lymphocyte migration into lung tissue in response to Pneumocystis carinii and depletes T lymphocyte numbers in the spleens of mice. Alcohol Clin Exp Res (in press)
21. Mufti S, Prabhala R, Moriguchi S, Sipes G, Watson R: Functional and numerical alterations induced by ethanol in the cellular immune system. Immunopharmacology 15:85-94, 1988
22. Meadows G, Wallendal M, Kosugi A, Wunderlich J, Singer D: Ethanol induces marked changes in lymphocyte populations and natural killer cell activity in mice. Alcohol Clin Exp Res 16:474-479, 1992
23. Watson R, Prabhala R, Abril E, Smith T: Changes in lymphocyte subsets and macrophage functions from high, short-term dietary ethanol in C57/BL6 mice. Life Sci 43:865-870, 1988
24. Saad J, Jerrells T: Flow cytometric and immunohistochemical evaluation of ethanol-induced changes in splenic and thymic lymphoid cell populations. Alcohol Clin Exp Res 15:796-803, 1991
25. Sibley D, Fuseler J, Slukvin I, Jerrells T: Ethanol-induced depletion of lymphocytes from the mesenteric lymph nodes of C57BL/6 mice is associated with RNA but not DNA degradation. Alcohol Clin Exp Res 19:324-331, 1995
26. Lopez M, Huang D, Borgs P, Wang Y, Watson R: Modification of lymphocyte subsets in the intestinal associated immune system and thymus by chronic ethanol consumption. Alcohol Clin Exp Res 18:8-11, 1994
27. Kaelin R, Semerjian A, Center D, Bernardo J: Influence of ethanol on human T-lymphocyte migration. J Lab Clin Med 104:752-760, 1984
28. Kim J, Woods A, Becker-Dunn E, Bottomly K: Distinct functional phenotypes of clone Ia-restricted helper T cells. J Exp Med 162:188-201, 1985
29. Mosmann T, Cherwinski H, Bond M, Giedlin M, Coffman R: Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 126:2348-2352, 1986
30. Swain S, Bradley L, Croft M, et al: Helper T cell subsets: Phenotype, function and roles of lymphokines in regulating their development. Immunol Rev 123:114-144, 1991
31. Cher D, Mosmann T: Two types of murine helper T cell clone. II. Delayed type hypersensitivity is mediated by Th1 clones. J Immunol 138:3688-3694, 1987
32. Killar L, MacDonald G, West J, Woods A, Bottomly K: Cloned Ia restricted T cells that do not produce IL4/BSF-1 fail to help antigen specific B cells. J Immunol 138:1674-1679, 1987
33. Manetti R, Parronchi P, Guidizi G, et al: Natural killer cell stimulatory factor (IL-12) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing T cells. J Exp Med 177:1199-1204, 1993
34. Maggi E, Parronchi P, Manetti R, et al: Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones. J Immunol 148:2142-2148, 1992
35. Heinzel F, Sadick M, Holaday B, Coffman R, Locksley R: Reciprocal expression of interferon-gamma or interleukin-4 during the resolution or progression of murine leishmaniasis. J Exp Med 169:59-72, 1989
36. Heinzel F, Rerko R, Hatam F, Locksley R: IL-2 is necessary for the progression of leishmaniasis in susceptible murine hosts. J Immunol 150: 3924-3931, 1993
37. Orme I, Roberts A, Griffin J, Abrams J: Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection. J Immunol 151:518-525, 1993
38. Hoag K, Street N, Huffnagle G, Lipscomb M: Early cytokine production in pulmonary Cryptococcus neoformans infections distinguishes susceptible and resistant mice. Am J Respir Cell Mol Biol 13:487-495, 1995
39. Yamamura M, Uyemura K, Deans R, et al: Defining protective responses to pathogens: Cytokine profiles in leprosy lesions. Science 254:277-279, 1991
40. Modlin R: Th1-Th2 paradigm: Insights from leprosy. J Invest Dermatol 102:828-832, 1994