Modulation of the induction of ornithine decarboxylase by some opioid receptor agonists in immune cells and cardiomyocytes

Molecular and Cellular Biochemistry

Volumn 185, Issue 1-2, 1998, Pages 47-53

  Pignatti, Carla ^a   Stanic', Ivana ^a   Stefanelli, Claudio ^a   Tantini, Benedetta ^a   Rossoni, Carmen ^a   Flamigni, Flavio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Cardiomyocytes; Leu enkephalin; Opioid; Ornithine decarboxylase; Thymocytes; U 50488H

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; CALCIMYCIN; CONCANAVALIN A; DELTA OPIATE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR ANTAGONIST; LEUCINE ENKEPHALIN; MESSENGER RNA; OPIATE AGONIST; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HEART MUSCLE CELL; IMMUNOCOMPETENT CELL; NONHUMAN; RAT; SPLEEN CELL; THYMOCYTE;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS, NON-NARCOTIC; ANIMALS; B-LYMPHOCYTES; CELLS, CULTURED; ENKEPHALIN, LEUCINE; ENZYME INDUCTION; IMMUNE SYSTEM; LIGANDS; MALE; MYOCARDIUM; ORGAN SPECIFICITY; ORNITHINE DECARBOXYLASE; RATS; RATS, WISTAR; RECEPTORS, OPIOID; RNA, MESSENGER; T-LYMPHOCYTES;

ANIMALIA;

EID: 0031688544     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006857027551     Document Type: Article

References (46)

1. Barg J, Belcheva MM, Coscia CJ: Evidence for the implication of phosphoinositol signal transduction in μ-opioid inhibition of DNA synthesis. J Neurochem 59: 1145-1152, 1992
2. Barg J, Nah S-Y, Levy R, Saya, D Vogel Z: Modulation of thymidine incorporation by κ-opioid ligands in rat spinal cord-dorsal root ganglion co-cultures. Brain Res 629: 109-114, 1993
3. Roda G, Bongiorno L, Trani E, Urbani A, Pirani M: Positive and negative immunomodulation by opioid peptides. Int J Immunopharmac 18: 1-16, 1996
4. Linner KM, Quist HE, Sharp BM: Met-enkephalin-containing peptide encoded by proenkephalin A mRNA expressed in activated murine thymocytes inhibit thymocyteproliferation. J Immunol 154: 5049-5060, 1995
5. Lawrence DMP, El-Hamouly W, Archer S, Leary JF, Bidlack JM: Identification of κ-opioid receptors in the immune system by indirect immunofluorescence. Proc Natl Acad Sci USA 92: 1062-1066, 1995
6. Gaveriaux C, Peluso J, Simonin F, Laforet J, Kieffer B: Identification of κ- and δ-opioid receptor transcripts in immune cells. FEBS Lett 369: 272-276, 1995
7. Seiler N, Atanassov CL: The natural polyamines and the immune system. Progress in Drug Research 43: 87-141, 1994
8. Thomas TJ, Gunnia UB, Seibold JR, Thomas T: Defective signal transduction pathways in T-cells from autoimmune MRL-Ipr/Ipr mice are associated with increased polyamine concentrations. Biochem J 311: 175-182, 1995
9. Heby O, Persson L: Molecular genetics of polyamine synthesis in eukaryotic cells. Trends Biochem Sci 15: 153-158, 1990
10. Hayashi S-I, Murakami Y: Rapid and regulated degradation of ornithine decarboxylase. Biochem J 306: 1-10, 1995
11. Pegg AE, Shantz LM,Coleman CS: Ornithine decarboxylase as a target for chemoprevention. J Cell Biochem 22: 132-138, 1995
12. Benalal D, Bachrach U: Opiates and cultured neuroblastoma xglioma cells. Biochem J 227: 389-395, 1985
13. Butler SR, Shanberg SM: Effect of maternal morphine administration on neonatal rat brain ornithine decarboxylase (ODC). Biochem Pharmacol 24: 1915-1918, 1975
14. Slotkin TA, Seidler FJ, Whitmore WL: Effects of maternal methadone administration on ornithine decarboxylase in brain and heart of the offspring: Relationships of enzyme activity to dose and to growth impairment in the rat. Life Sci 26: 861-867, 1980
15. Bartolome JV, Wang S, Bartolome MB: Transcription-dependent and independent regulation of hepatic ornithine decarboxylase activity by CNS β-endorphin in rat pups.Mol Brain Res 33: 149-156, 1995
16. Bartolome JV, Chang K-J, Bartolome MB: The inhibition of ornithine decarboxylase activity in developing rat tissues by central nervous system β-endorphin is mediated by μ-opioid receptors, but not by δ-or ε-opioid receptors. Eur J Pharmacol 284: 43-50, 1995
17. Laurent S, Marsh JD, Smith TW: Enkephalins increase cyclic adenosine monophosphate content, calcium uptake, and contractile state in cultured chick embryo heart cells. J Clin Invest 77: 1436-1440, 1986
18. 2+ release from an intracellular pool in myocytes and neurons. Circulation Res 70: 66-81, 1992
19. Springhorn JP, Claycomb WC: Preproenkephalin mRNA expression in developing rat heart and in cultured ventricular cardiac muscle cells. Biochem J 258: 73-78, 1989
20. Ventura C, Guarnieri C, Vaona I, Campana G, Pintus G, Spampinato S: Dynorphin gene expression and release in the myocardial cell. J Biol Chem 269: 5382-5386, 1994
21. Flamigni F, Campana G, Carboni L, Guarnieri C, Spampinato S: Zinc is required for the expression of ornithine decarboxylase in a difluoromethylornithine-resistant cell line. Biochem J 299: 515-519, 1994
22. Hyttinen J-M, Halmekytö M, Alhonen L, Jänne J: Levels of ornithine decarboxylase genomic sequences, heterogeneous nuclear RNA and mRNA in human myeloma cells resistant to α- difluoromethylornithine. Biochem J 278: 871-874, 1991
23. Chomczynsky P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocianate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987
24. Flamigni F, Stefanelli C, Stanic' I, Muscari C, Giaccari A, Rossoni C: Inhibition of the expression of ornithine decarboxylase by some κ-opioidergic receptor ligands in difluoromethylornithine-resistant L1210 cells. Biochim Biophys Acta 1311: 204-210, 1996
25. Brand C: Role of ornithine decarboxylase on glycolytic enzyme induction during thymocyte proliferation. J Biol Chem 262: 15232-15235, 1987
26. Stefanelli C, Rossoni C, Ferrari F, Flamigni F, Caldarera CM: Ornithine decarboxylase and ornithine decarboxylase-inhibiting activity in rat thymocytes. Cell Biochem Funct 10: 243-250, 1992
27. Vonvoigtlander PF, Lahti RA, Ludens JH: U-50,488: A selective and structural novel non- mu (kappa) opioid agonist. J Pharmacol Exp Ther 224: 7-12, 1983
28. De Costa BR, Bowen WD, Hellewell SB, George C, Rothman RB, Reid AA, Walker JM, Jacobson AE, Rice KC: Alterations in the stereochemistry of the κ- selective opioid agonist U50,488H result in high affinity σ ligands. J Med Chem 32: 1996-2002, 1989
29. Takemori AE, Ho BY, Naeseth JS, Portoghese PS: Nor-binaltorphimine, a high selective kappa-opioid antagonist in analgesic and receptor binding assay. J Pharmacol Exp Ther 246: 255-258, 1988
30. James IF, Goldstein A: Site-directed alakylation of multiple opioid receptors. Mol Pharmacol 25: 337-342, 1984
31. Wallon MU, Persson L, Heby O: Superinduction of ornithine decarboxylase (ODC) by actinomycin D is due to stimulation of ODC mRNA translation. FEBS left 268: 161-164, 1990
32. Ventura C, Guarnieri C, Stefanelli C, Cirielli C, Lakatta EG, Capogrossi MC: Comparison between alpha-adrenergic- and κ-opioidergic-mediated inositol (1, 4, 5) P3/inositol (1, 3, 4, 5) P4 formation in adult cultured rat ventricular cardiomyocytes. Biochem Biophys Res Commun 179: 972-978, 1991
33. Shayovits A, Bachrach U: Ornithine decarboxylase: An indicator for growth of NIH 3T3 fibroblasts and their c-Ha-ras transformants. Biochim Biophys Acta 1267: 107-114, 1995
34. Caroleo MC, Arbitrio M, Melchiorri D, Nistico G: A reappraisal of the role of the various opioid receptor subtypes in cell-mediated immunity. Neuroimmunomodulation 1: 141-147, 1994
35. Hayes AG, Birch PP, Cavicchini E: Evidence that the kappa agonist U50488H has non-opioid actions. J Pharm Pharmacol 40: 718-720, 1988
36. 2+ uptake into cultured bovine adrenal medullary cells. Biochem Pharmacol 41: 715-722, 1991
37. Periyasamy S, Hoss W: Inhibition of carbachol-stimulated phosphoinositide turnover by U-50,488H in rat hippocampus-involvement of GTP-binding protein. Eur J Pharmacol 207: 101-109, 1991.
38. Ralevic V, Rubino A, Burnstock G: Prejunctional modulation of sensory-motor nerve-mediated vasodilation of the rat mesenteric arterial bed by opioid peptides. J Pharmacol Exp Ther 268: 772-778, 1994
39. Pugsley MK, Saint DA, Walkner MJA: An electrophysiological basis for the antiarrhythmic actions of the κ-opioid receptor agonist U-50488H. Eur J Pharmacol 261: 303-309, 1994
40. Carr DJJ, De Costa BR, Radesca L, Blalock JE: Functional assessment and partial characterization of [H-3](+)-Pentazocine binding sites on cells of the immune system. J Neuroimmunol 35: 153-166, 1991
41. Garza HH, Mayo S, Bowen WD, De Costa BR, Carr DJJ: Characterization of a (+)-azido phenazocine-sensitive sigma-receptor on splenic lymphocytes. J Immunol 151: 4672-4680, 1993
42. Carr DJJ, De Costa BR, Kim CH, Jacobson AE, Guarcello V, Rice KC, Blalock JE: Opioid receptors on cells of the immune system: Evidence for delta- and kappa-classes. J Endocrinol 122: 161-168, 1989
43. Carr DJJ, Rogers TJ, Weber RJ: The relevance of opioids and opioid receptors onimmunocompetence and immune homeostasis. Proc Soc Exp Biol Med 213: 248-259, 1996
44. Mollerau C, Parmentier M, Maillieux P, Butour J-L, Moisand C, Chalon P, Caput D, Vassart G, Meuiner J-C: ORL-1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS left 341:33-38, 1994
45. Halford WP, Gebhardt BM, Carr DJJ: Functional role and sequence analysis of a lymphocyte orphan opioid receptor. J Neuroimmunol 59: 91-102, 1996
46. Knapp RS, Malatynska E, Collins N, Fang L, Wang JY, Hruby VJ, Roeske WR, Yamamura HI: Molecular biology and pharmacology of cloned opioid receptors. FASEB J 9: 516-525, 1995