-
1
-
-
0026646771
-
Thrombomodulin is preferentially expressed in BALB/c lung microvessels
-
Ford, V. A., Stringer, C., and Kennel, S. J. (1992) Thrombomodulin is preferentially expressed in BALB/c lung microvessels. J. Biol. Chem. 267, 5445-5450.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 5445-5450
-
-
Ford, V.A.1
Stringer, C.2
Kennel, S.J.3
-
2
-
-
0011760442
-
Rat monoclonal antibody distribution in mice: An epitope inside the lung vascular space mediates very efficient localization
-
Kennel, S. J., Lee, R., Bultman, S., and Kabalka, G. (1990) Rat monoclonal antibody distribution in mice: an epitope inside the lung vascular space mediates very efficient localization. Nucl. Med. Biol. 17, 193-200.
-
(1990)
Nucl. Med. Biol.
, vol.17
, pp. 193-200
-
-
Kennel, S.J.1
Lee, R.2
Bultman, S.3
Kabalka, G.4
-
3
-
-
0025346213
-
Lipid composition is important for highly efficient target binding and retention of immunoliposomes
-
Maruyama, K., Kennel, S., and Huang, L. (1990) Lipid composition is important for highly efficient target binding and retention of immunoliposomes. Proc. Natl. Acad. Sci. USA 87, 5744-5748.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5744-5748
-
-
Maruyama, K.1
Kennel, S.2
Huang, L.3
-
4
-
-
0026668198
-
Cationic liposomes enhance targeted delivery and expression of exogenous DNA mediated by N-terminal modified poly(l-lysine)-antibody conjugate in mouse lung endothelial cells
-
Trubetskoy, V. S., Torchilin, V. P., Kennel, S. J., and Huang, L. (1992) Cationic liposomes enhance targeted delivery and expression of exogenous DNA mediated by N-terminal modified poly(l-lysine)-antibody conjugate in mouse lung endothelial cells. Biochim. Biophys. Acta 1131, 311-313.
-
(1992)
Biochim. Biophys. Acta
, vol.1131
, pp. 311-313
-
-
Trubetskoy, V.S.1
Torchilin, V.P.2
Kennel, S.J.3
Huang, L.4
-
5
-
-
0024558370
-
The role of protein C and thrombomodulin in the regulation of blood cloagulation
-
Esmon, C. T. (1989) The role of protein C and thrombomodulin in the regulation of blood cloagulation. J. Biol. Chem. 264, 4743-4746.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 4743-4746
-
-
Esmon, C.T.1
-
6
-
-
0027445999
-
Protein C activation
-
Esmon, C., Esmon, N., Le Bonniec, B., and Johnson, A. (1993) Protein C activation. Methods Enzymol. 222, 359-385.
-
(1993)
Methods Enzymol.
, vol.222
, pp. 359-385
-
-
Esmon, C.1
Esmon, N.2
Le Bonniec, B.3
Johnson, A.4
-
7
-
-
0023654011
-
Proteolytic formation and properties of functional domains of thrombomodulin
-
Kurosawa, S., Galvin, J., Esmon, N., and Esmon, C. (1987) Proteolytic formation and properties of functional domains of thrombomodulin. J. Biol. Chem. 262, 2206-2212.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 2206-2212
-
-
Kurosawa, S.1
Galvin, J.2
Esmon, N.3
Esmon, C.4
-
8
-
-
0029112841
-
Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface
-
Esmon, C. (1995) Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface. FASEB J. 9, 946-955.
-
(1995)
FASEB J.
, vol.9
, pp. 946-955
-
-
Esmon, C.1
-
9
-
-
0023374585
-
Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation
-
Suzuki, K., Kusomoto, H., Deyashiki, Y., Hishioka, J., Maruyama, I., Zushi, M., Kawahara, S., Honda, G., Yamamoto, S., and Horiguchi, S. (1987) Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation, EMBO J. 6, 1891-1902.
-
(1987)
EMBO J.
, vol.6
, pp. 1891-1902
-
-
Suzuki, K.1
Kusomoto, H.2
Deyashiki, Y.3
Hishioka, J.4
Maruyama, I.5
Zushi, M.6
Kawahara, S.7
Honda, G.8
Yamamoto, S.9
Horiguchi, S.10
-
10
-
-
0027374598
-
Identification of the predomonant glycosaminoglycan-attachment site in soluble recombinant human thrombomodulin: Potential regulation of functionality by glycosaminoglycane competition for Serine 474
-
Gerlitz, B., Hassell, T., Vlahos, C. J., Parkinson, J. F., Bang, N. U., and Grinnell, B. W. (1993) Identification of the predomonant glycosaminoglycan-attachment site in soluble recombinant human thrombomodulin: potential regulation of functionality by glycosaminoglycane competition for Serine 474. Biochem. J. 295, 131-140.
-
(1993)
Biochem. J.
, vol.295
, pp. 131-140
-
-
Gerlitz, B.1
Hassell, T.2
Vlahos, C.J.3
Parkinson, J.F.4
Bang, N.U.5
Grinnell, B.W.6
-
11
-
-
0026769410
-
Structure-function studies of the epidermal growth factor domains of human thrombomodulin
-
Parkinson, J., Nagashima, M., Kuhn, I., Leonard, J., and Morser, J. (1992) Structure-function studies of the epidermal growth factor domains of human thrombomodulin. Biochem. Biophys. Res. Commun. 185, 567-576.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.185
, pp. 567-576
-
-
Parkinson, J.1
Nagashima, M.2
Kuhn, I.3
Leonard, J.4
Morser, J.5
-
12
-
-
0026506310
-
Recombinant human thrombomodulin: Regulation of cofactor activity and anticoagulant function by a glycosaminoglycan side chain
-
Parkinson, J. F., Vlahos, C. J., Yan, S. C., and Bang, N. U. (1992) Recombinant human thrombomodulin: regulation of cofactor activity and anticoagulant function by a glycosaminoglycan side chain. Biochem. J. 283, 151-157.
-
(1992)
Biochem. J.
, vol.283
, pp. 151-157
-
-
Parkinson, J.F.1
Vlahos, C.J.2
Yan, S.C.3
Bang, N.U.4
-
13
-
-
0027407874
-
The chondroitin sulfate moiety of thrombomodulin binds a second molecule of thrombin
-
Ye, J., Esmon, C. T., and Johnson, A. E. (1993) The chondroitin sulfate moiety of thrombomodulin binds a second molecule of thrombin. J. Biol. Chem. 268, 2373-2379.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2373-2379
-
-
Ye, J.1
Esmon, C.T.2
Johnson, A.E.3
-
14
-
-
0028338559
-
Glycosaminoglycan contributions to both protein C activation and thrombin inhibition involve a common arginine-rich site in thrombin that includes residues arginine 93, 97 and 101
-
Ye, J., Rezale, A. R., and Esmon, C. T. (1994) Glycosaminoglycan contributions to both protein C activation and thrombin inhibition involve a common arginine-rich site in thrombin that includes residues arginine 93, 97 and 101. J. Biol. Chem. 269, 17965-17970.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17965-17970
-
-
Ye, J.1
Rezale, A.R.2
Esmon, C.T.3
-
15
-
-
0028019030
-
Modulation of glycosaminoglycan addition in naturally expressed and recombinant human thrombomodulin
-
Lin, J. H., McLean, K., Morser, J., Young, T. A., Wydro, R. M., Adrews, W. H., and Light, D. R. (1994) Modulation of glycosaminoglycan addition in naturally expressed and recombinant human thrombomodulin. J. Biol. Chem. 269, 25021-25030.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25021-25030
-
-
Lin, J.H.1
McLean, K.2
Morser, J.3
Young, T.A.4
Wydro, R.M.5
Adrews, W.H.6
Light, D.R.7
-
16
-
-
0026775230
-
Functional domains of membrane-bound human thrombomodulin: EGF-like domains four to six and Ser/Thr-rich domain are required for cofactor activity
-
Tsiang, M., Lentz, S. R., and Sadler, J. E. (1992) Functional domains of membrane-bound human thrombomodulin: EGF-like domains four to six and Ser/Thr-rich domain are required for cofactor activity. J. Biol. Chem. 267, 6164-6170.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 6164-6170
-
-
Tsiang, M.1
Lentz, S.R.2
Sadler, J.E.3
-
17
-
-
0027413493
-
Role of the glycoaminoglycan component of thrombomodulin in its accleration of the inactivation of single-chain urokinase-type plasminogen activator by thrombin
-
de Munk, G. A., Parkinson, J. F., Groeneveld, E., Bang, N. U., and Rijken, D. C. (1993) Role of the glycoaminoglycan component of thrombomodulin in its accleration of the inactivation of single-chain urokinase-type plasminogen activator by thrombin. Biochem. J. 290, 655-659.
-
(1993)
Biochem. J.
, vol.290
, pp. 655-659
-
-
De Munk, G.A.1
Parkinson, J.F.2
Groeneveld, E.3
Bang, N.U.4
Rijken, D.C.5
-
18
-
-
0022371596
-
The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells: Endocytosis and degradation of thrombin
-
Maruyama, I., and Majerus, P. W. (1985) The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells: endocytosis and degradation of thrombin. J. Biol. Chem. 260, 15432-15438.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 15432-15438
-
-
Maruyama, I.1
Majerus, P.W.2
-
19
-
-
0026465092
-
Antibodies to thrombomodulin induce receptor-mediated endocytosis in human saphenous vein endothelial cells
-
Brisson, G., Archipoff, G., Hartmann, M. L., Hanau, D., Beretz, A., Freyssinet, J. M., and Cazenave, J. P. (1992) Antibodies to thrombomodulin induce receptor-mediated endocytosis in human saphenous vein endothelial cells. Thromb. Haemost. 68, 737-743.
-
(1992)
Thromb. Haemost.
, vol.68
, pp. 737-743
-
-
Brisson, G.1
Archipoff, G.2
Hartmann, M.L.3
Hanau, D.4
Beretz, A.5
Freyssinet, J.M.6
Cazenave, J.P.7
-
20
-
-
0027490521
-
Thrombomodulin and thrombin localization on the vascular endothelium: Their internalization and transcytosis by plasmalemmal vesicles
-
Horwat, R., and Palade, G. E. (1993) Thrombomodulin and thrombin localization on the vascular endothelium: their internalization and transcytosis by plasmalemmal vesicles. Eur. J. Cell Biol. 61, 299-313.
-
(1993)
Eur. J. Cell Biol.
, vol.61
, pp. 299-313
-
-
Horwat, R.1
Palade, G.E.2
-
21
-
-
0026647573
-
An ultrastructural study of thrombomodulin endocytosis: Internalization occurs via clathrin-coated and non-coated pits
-
Conway, E. M., Boffa, M. C., Nowakowski, B., and Steiner-Mosonyi, M. (1992) An ultrastructural study of thrombomodulin endocytosis: internalization occurs via clathrin-coated and non-coated pits. J. Cell. Physiol. 151, 604-612.
-
(1992)
J. Cell. Physiol.
, vol.151
, pp. 604-612
-
-
Conway, E.M.1
Boffa, M.C.2
Nowakowski, B.3
Steiner-Mosonyi, M.4
-
22
-
-
0028039927
-
Thrombomodulin lacking the cytoplasmic domain efficiently internalizes thrombin via clathrin-coated, pit-mediated endocytosis
-
Conway, E. M., Nowakowski, B., and Steiner-Mosonyi, M. (1994) Thrombomodulin lacking the cytoplasmic domain efficiently internalizes thrombin via clathrin-coated, pit-mediated endocytosis. J. Cell. Biol. 158, 285-298.
-
(1994)
J. Cell. Biol.
, vol.158
, pp. 285-298
-
-
Conway, E.M.1
Nowakowski, B.2
Steiner-Mosonyi, M.3
-
23
-
-
0028580250
-
Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain
-
Teasdale, M. S., Bird, C. H., and Bird, P. (1994) Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain. Immunol. Cell Biol. 72, 480-488.
-
(1994)
Immunol. Cell Biol.
, vol.72
, pp. 480-488
-
-
Teasdale, M.S.1
Bird, C.H.2
Bird, P.3
-
24
-
-
0024589205
-
Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture
-
Moore, K. L., Esmon, C. T., and Esmon, N. L. (1989) Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture. Blood 73, 159-165.
-
(1989)
Blood
, vol.73
, pp. 159-165
-
-
Moore, K.L.1
Esmon, C.T.2
Esmon, N.L.3
-
25
-
-
0026345948
-
Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocystein
-
Lentz, S. R., and Sadler, J. E. (1991) Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocystein. J. Clin. Invest. 88, 1906-1914.
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 1906-1914
-
-
Lentz, S.R.1
Sadler, J.E.2
-
26
-
-
0025755359
-
Regulatory mechanisms for thrombomodulin expression in human umbilical vein endothelial cells
-
Hirokawa, K., and Aoki, N. (1991) Regulatory mechanisms for thrombomodulin expression in human umbilical vein endothelial cells. J. Cell. Physiol. 147, 157-165.
-
(1991)
J. Cell. Physiol.
, vol.147
, pp. 157-165
-
-
Hirokawa, K.1
Aoki, N.2
-
27
-
-
0023274160
-
Protein C inhibits endocytosis of thrombin/thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells
-
Maruyama, I., and Majerus, P. W. (1987) Protein C inhibits endocytosis of thrombin/thrombomodulin complexes in A549 lung cancer cells and human umbilical vein endothelial cells. Blood 69, 1481-1484.
-
(1987)
Blood
, vol.69
, pp. 1481-1484
-
-
Maruyama, I.1
Majerus, P.W.2
-
28
-
-
0000650903
-
Identification of an endothelial cell co-factor for thrombin-catalyzed activation of protein C
-
Esmon, C., and Owen, W. (1981) Identification of an endothelial cell co-factor for thrombin-catalyzed activation of protein C. Proc. Natl. Acad. Sci. USA 78, 2249-2252.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 2249-2252
-
-
Esmon, C.1
Owen, W.2
-
29
-
-
0024591263
-
Stability of the thrombin-endothelial complex on the surface of the thrombin-thrombomodulin complex on the surface of endothelial cells from human saphenous vein or from the cell line EA.hy 929
-
Beretz, A., Freyssinet, J., Gauchy, J., Scmitt, D., Klein-Soyer, C., Edgell, C., and Cazenave, J. (1989) Stability of the thrombin-endothelial complex on the surface of the thrombin-thrombomodulin complex on the surface of endothelial cells from human saphenous vein or from the cell line EA.hy 929. Biochem. J. 259, 35-40.
-
(1989)
Biochem. J.
, vol.259
, pp. 35-40
-
-
Beretz, A.1
Freyssinet, J.2
Gauchy, J.3
Scmitt, D.4
Klein-Soyer, C.5
Edgell, C.6
Cazenave, J.7
-
31
-
-
0028922434
-
The functional effects of biotinylation of anti-ACE monoclonal antibody in terms of targeting in vivo
-
Muzykantov, V., Gavriluk, V., Reinecke, A., Atochina, E., Kuo, A., Barnathan, E., and Fisher, A. (1995) The functional effects of biotinylation of anti-ACE monoclonal antibody in terms of targeting in vivo. Anal. Biochem. 226, 279-287.
-
(1995)
Anal. Biochem.
, vol.226
, pp. 279-287
-
-
Muzykantov, V.1
Gavriluk, V.2
Reinecke, A.3
Atochina, E.4
Kuo, A.5
Barnathan, E.6
Fisher, A.7
-
32
-
-
0027255975
-
Purification of radiolabeled monoclonal antibody against ACE significantly improves specificity and efficiency of targeting into the lung
-
Hiemish, H., Gavriluk, V., Atochina, E., Slinkin, M., Torchilin, V., Muzykantov, V., and Danilov, S. (1993) Purification of radiolabeled monoclonal antibody against ACE significantly improves specificity and efficiency of targeting into the lung. Nucl. Med. Biol. 20, 435-444.
-
(1993)
Nucl. Med. Biol.
, vol.20
, pp. 435-444
-
-
Hiemish, H.1
Gavriluk, V.2
Atochina, E.3
Slinkin, M.4
Torchilin, V.5
Muzykantov, V.6
Danilov, S.7
-
33
-
-
0015822275
-
Culture of human endothelial cells derived from umbilical vein
-
Jaffe, E., Nachman, R., Becker, C., and Minick, C. (1973) Culture of human endothelial cells derived from umbilical vein. J. Clin. Invest. 52, 2745-2756.
-
(1973)
J. Clin. Invest.
, vol.52
, pp. 2745-2756
-
-
Jaffe, E.1
Nachman, R.2
Becker, C.3
Minick, C.4
-
34
-
-
13144288714
-
Stimulation of cultured human vascular endothelial cell proliferation by growth factor from human brain, heparin and thrombin
-
Abstr.
-
Danilov, S., Allikmets, E., and Martynov, A. (1983) Stimulation of cultured human vascular endothelial cell proliferation by growth factor from human brain, heparin and thrombin. J. Cell. Biol. 99:274 (Abstr.).
-
(1983)
J. Cell. Biol.
, vol.99
, pp. 274
-
-
Danilov, S.1
Allikmets, E.2
Martynov, A.3
-
35
-
-
0029939735
-
Endothelial cells internalize monoclonal antibody to angiotension-converting enzyme
-
Muzykantov, V., Atochina, E., Kuo, A., Barnathan, E., Notarfrancesco, K., Shuman, H., Dodia, C., and Fisher, A. (1996) Endothelial cells internalize monoclonal antibody to angiotension-converting enzyme. Am. J. Physiol. 270, L704-L713.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Muzykantov, V.1
Atochina, E.2
Kuo, A.3
Barnathan, E.4
Notarfrancesco, K.5
Shuman, H.6
Dodia, C.7
Fisher, A.8
-
36
-
-
0024542757
-
Monoclonal antibodies to thrombomodulin whose binding is calcium dependent
-
Tokyo
-
Kimura, S., Nagoya, T., and Aoki, N. (1989) Monoclonal antibodies to thrombomodulin whose binding is calcium dependent. J. Biochem. (Tokyo) 105, 478-783.
-
(1989)
J. Biochem.
, vol.105
, pp. 478-783
-
-
Kimura, S.1
Nagoya, T.2
Aoki, N.3
-
37
-
-
0031023957
-
The amino terminal lectin-like domain of thrombomodulin is required for constitutive endocytosis
-
Conway, E. M., Pollefeyt, S., Collen, D., and Steiner-Mosonyl, M. (1997) The amino terminal lectin-like domain of thrombomodulin is required for constitutive endocytosis. Blood 89, 652-661.
-
(1997)
Blood
, vol.89
, pp. 652-661
-
-
Conway, E.M.1
Pollefeyt, S.2
Collen, D.3
Steiner-Mosonyl, M.4
-
38
-
-
0030433178
-
Targeting of antibody-conjugated plasminogen activators to the pulmonary vasculature
-
Muzykantov, V., Barnathan, E., Atochina, E., Danilov, S., and Fisher, A. (1996) Targeting of antibody-conjugated plasminogen activators to the pulmonary vasculature. J. Pharmacol. Exp. Ther. 279, 1026-1034.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.279
, pp. 1026-1034
-
-
Muzykantov, V.1
Barnathan, E.2
Atochina, E.3
Danilov, S.4
Fisher, A.5
-
39
-
-
0026569489
-
The glycosaminoglycan of recombinant human soluble thrombomodulin affect antithrombotic activity in a rat model of tissue factor-induced disseminated intravascular coagulation
-
Nawa, K., Itani, T., Ono, M., Sakano, K., Marumoto, Y., and Iwamoto, M. (1992) The glycosaminoglycan of recombinant human soluble thrombomodulin affect antithrombotic activity in a rat model of tissue factor-induced disseminated intravascular coagulation. Thromb. Haemost. 67, 366-370.
-
(1992)
Thromb. Haemost.
, vol.67
, pp. 366-370
-
-
Nawa, K.1
Itani, T.2
Ono, M.3
Sakano, K.4
Marumoto, Y.5
Iwamoto, M.6
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