Fetal cells in maternal blood: Review of the literature;CELLULES FOETALES DANS LE SANG MATERNAL: VERS UN DIAGNOSTIC ANTENATAL NON INVASIF? REVUE DE LA LITTERATURE

Journal de Gynecologie Obstetrique et Biologie de la Reproduction

Volumn 27, Issue 5, 1998, Pages 483-493

  Houfflin Debarge, V ^a   Delsalle, A ^b   Subtil, D ^a   Mannessier, L ^b   Codaccioni, X ^a   Puech, F ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b Lab d'Histocompatibilité   (France)

Author keywords

Antenatal diagnosis; Fetal cells; FISH; Nucleated red blood cells; PCR

Indexed keywords

AMNIOCENTESIS; ANEUPLOIDY; CELL SELECTION; CHORION VILLUS SAMPLING; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; FEMALE; FETUS; FETUS CELL; FLUORESCENCE IN SITU HYBRIDIZATION; HEMOGLOBINOPATHY; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MATERNAL BLOOD; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS; REVIEW; RHESUS INCOMPATIBILITY; SAMPLING; SEX DETERMINATION; TECHNIQUE; UMBILICAL CORD BLOOD;

EID: 0031687528     PISSN: 03682315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (83)

1. Miller WA, Maddow JE. When is it appropriate to apply fetal cell isolation clinically ? Am J Obstet Gynecol 1995; 172 (3): 1064-5.
2. Schmorl G. Pathologische - anatomisghe Untersuchungen über puerperal eklampsie. Leipzig, Vogel, 1893.
3. Douglas GW, Thomas L, Carr M, Cullen NM, Morris R. Trophoblast in the circulating blood during pregnancy. Am J Obstet Gynecol 1959;78:960-9.
4. Attwood HD, Park WW. Embolism to the lungs by trophoblast. J Obstet Gynaecol Br Cwealth 1961;68:611-7.
5. Walknowska J, Conte FA, Grumbach MM. Practical and theorical implications of fetal/maternal lymphocyte transfer. Lancet 1969;i:1119-22.
6. De Grouchy J, Trubuchet C. Transfusion foetomatemelle de lymphocytes sanguins et détection du sexe du fœtus. Ann Gene 1971;14:133-7.
7. Schindler AM, Graf E, Martin Du Pan R. Prenatal diagnosis of fetal lymphocytes in the maternal blood. Obstet Gynecol 1972;40:340-6.
8. Takahara H, Kadotani I. Some critical aspects of prenatal diagnosis of sex in leukocyte cultures from pregnant women. Proc Jpn Acad 1972;48:603-7.
9. Lo YMD. Non invasive prenatal diagnosis using fetal cells in maternal blood. J Clin Pathol 1994;47 (12):1060-5.
10. Ganshirt-Alhert D, Pohlschmidt M, Gal A, Miny P, Horst J, Holzgreve W. Ratio of fetal to maternal DNA is less than 1/5 000 at different gestationnal ages in maternal blood. Clin Genet 1990;38:38-43.
11. Price JO, Elias S, Wachtel SS, Klinger K, Dockter M, Tharapel A et al. Prenatal diagnosis using fetal cells isolated from maternal blood by multiparameter flow cytometry. Am J Obstet Gynecol 1991;165:1731-7.
12. Simpson JL, Elias S. Isolating fetal cells in maternal circulation for prenatal diagnosis. Prenat Diagn 1994;14:1229-42.
13. Bianchi DW, Williams JM, Sullivan LM, Hanson FW, Klinger KW, Shuber AP. PCR quantification of fetal cells in maternal blood in normal and aneuploid pregnancies. Am J Hum Genet 1997;61:822-9.
14. Covone AE, Johnson PM, Mutton D, Adinolfi M. Trophoblast cells in peripheral blood from pregnant women. Lancet 1984;2:841-3.
15. Covone AE, Kozma R, Johnson PM, Latt SA, Adinolfi M. Analysis of peripheral maternal blood samples for the presence of placental derived cells using Y specific probes and McAb H315. Prenat Diagn 1988;8:591-607.
16. Adinolfi M. A non invasive approach to prenatal diagnosis based on the detection of fetal nucleated cells in maternal blood samples. Prenat Diagn 1991;11:799-804.
17. Holzgreve W, Garritsen HSP, Ganshirt-Ahlert D. Fetal cells in the maternal circulation. J Reprod Med Obstet Gynecol 1992;37:410-8.
18. Bruch JF, Metezeau P, Garcia-Fonknechten N, Richard Y, Tricottet V, Hsi BL et at. Trophoblast like cells sorted from peripheral maternal blood using flow cytometry: a multiparametric study involving transmission electron microscopy and fetal DNA amplification. Prenat Diagn 1991;11:787-98.
19. Cacheux V, Milesi-Fluet C, Tachdjian G et al. Detection of 47 XYY trophoblast fetal cells in maternal blood by fluorescence in situ hybridization after using immunomagnetic lymphocyte depletion and flow cytometry sorting. Fetal Diagn Ther 1992;7:190-4.
20. Sargent IL, Johansen M, Chua S, Redman CWG. Clinical experience: isolating trophoblast from maternal blood. In : Simpson JL, Elias S (Eds). Fetal cells in maternal blood : Prospects for non invasive diagnosis, New York. New York Academy of sciences 1994;731:154-61.
21. Sbracia M, Scarpellini F, Lalwani S, Grasso JA, Scarpelli L. Possible use of an unusual HLA antigen to select trophoblast cells from the maternal circulation to perform early prenatal diagnosis. In : Simpson JL, Elias S (Eds). Fetal cells in maternal blood: Prospects for non invasive diagnosis, New York. New York Academy of sciences 1994;731:170-4.
22. Tse DB, Anderson P, Goldbard S, Gown AM, Hawes CS, Donnenfeld A. Characterization of trophoblast reactive monoclonal antibodies by flow cytometry and their application for fetal cell isolation. In : Simpson JL, Elias S. (Eds). Fetal cells in maternal blood: prospects for non invasive prenatal diagnosis, New York : New York Academy of science 1994;731:162-9.
23. Yagel S, Shpan P, Dushnik M, Livni N, Shimonovitz S. Trophoblasts circulating in maternal blood as candidates for prenatal genetic evaluation. Hum Reprod 1994;9:1184-9.
24. Yoshiki T, Yang YY, Lee Y, Lee CY. Generation and characterization of monoclonal antibodies specific to surface antigens of human trophoblast cells. Am J Reprod Immunol 1995;34 (3):148-55.
25. Mueller UW, Hawes CS, Wright AE, Petropoulos A, De Boni E, Firgaira FA et al. Isolation of fetal trophoblast cells from peripheral blood of pregnant women. Lancet 1990;336:197-200.
26. Weissman M, Ylinen K, Knuutila S. Fetal granulocytes in maternal venous blood detected by in situ hybridization. Prenat Diagn 1992;12:993-1000.
27. Herzenberg LA, Bianchi DW, Schroder J, Cann HM, Iverson GM. Fetal cells in the blood of pregnant women : detection and enrichment by fluorescence activated cell sorting. Proc Nattl Acad Sci USA 1979;76:1453-5.
28. Tharapel AT, Jaswaney V, Dockter M. Can fetal cells in maternal blood be selected through cytogenetic means ? Am J Hum Genet 1989;45 (suppl):271.
29. Yeoh SC, Sargent IL, Redman CW, Wordsworth BP, Thein SL. Detection of fetal cells in maternal blood. Prenat Diagn 1991;11:117-23.
30. Tharapel AT, Jaswaney VL, Dockter ME. Failure to detect fetal metaphases in lymphocytes flow sorted by maternal fetal HLA differences. Fetal Diagn Ther 1993;8:95-101.
31. Sargent IL, Choo YS, Redman CWG. Isolating and analyzing fetal leukocytes in maternal blood. In : Simpson JL, Elias S (Eds). Fetal cells in maternal blood : Prospects for non invasive diagnosis, New York. New York Academy of sciences 1994;731:147-53.
32. Langlois S, Wilson RD. Non invasive prenatal fetal testing by analysis of maternal blood. Clin Invest Med 1993;16/5: 333-8.
33. Bianchi DW, Flint AF, Pizzimenti MF, Knoll JHM, Latt SA. Isolation of fetal DNA from nucleated erythrocytes in maternal blood. Proc Natl Acad Sci USA 1990;87:3279-83.
34. Bianchi DW. Prenatal diagnosis by analysis of fetal cells in maternal blood. J Pediatr 1995;127:847-56.
35. Simpson JL, Elias S. Isolating fetal cells from maternal blood : advances in prenatal diagnosis through molecular technology. J Am Med Ass 1993;270:2357-61.
36. Ganshirt-Ahlert D, Borjesson-Stoll R, Burschyk M, Dohr A, Garritsen HSP, Helmer E et al. Detection of fetal trisomies 21 and 18 from maternal blood using triple gradient and magnetic cell sorting. Am J Reprod Immunol 1993;30/2 - 3:194-200.
37. Zheng YL, Demaria M, Zhen D, Vadnais TJ, Bianchi DW. Flow sorting of fetal erythroblasts using intracytoplasmic anti fetal haemoglobin: preliminary observations on maternal samples. Prenat Diagn 1995;15:897-905.
38. Bianchi DW, Zickwolf GK, Yih MC, Flint AF, Geifman OH, Erikson M et al. Erythroid-specific antibodies enhance detection of fetal nucleated erythrocytes in maternal blood. Prenat Diagn 1993;13/4:293-300.
39. Bianchi DW, Yih MC, Zickwolf GK, Flint MA. Transferrin receptor (CD71) expression on circulating mononuclear cells during pregnancy. Am J Obstet Gynecol 1994;170:202-6.
40. Lo YMD, Patel P, Sampietro M, Gilmer MDG, Fleming KA, Wainscoat JS. Detection of single copy fetal DNA sequence from maternal blood. Lancet 1990;335:1463-4.
41. Thomas MR, Williamson R, Craft I, Yazdani N, Rodeck CH. Y chromosome sequence DNA amplified from peripheral blood of women in early pregnancy. Lancet 1994;343:413-4.
42. Liou JD, Pao CC, Hor JJ, Kao SM. Fetal cells in the maternal circulation during first trimester in pregnancies. Hum Genet 1993;92:309-11.
43. Takabayashi H, Kuwara S, Ukita T, Ikawa K, Yamafugi K, Igarashi T. Development of non invasive fetal DNA diagnosis from maternal blood. Prenat Diagn 1995;15:74-7.
44. Bianchi DW, Stewart JE, Garber MF, Lucotte G, Flint AF. Possible effect of gestational age on the detection of fetal nucleated erythrocytes in the maternal blood. Prenat Diagn 1991;11/8:523-8.
45. Ganshirt-Ahlert D, Borjesson Stoll M, Burschyk M, Dohr A, Garritsen HSP, Helmer L et al. Non invasive prenatal diagnosis : triple density gradient, magnetic cell sorting and FISH prove to be an efficient and reproducible method for detection of fetal aneuploïdies from maternal blood. Am J Hum Genet 1992;51:A48.
46. Ganshirt-Ahlert D, Garritsen H, Miny P, Holzgreve W. Fetal cells in maternal circulation throughout gestation. Lancet 1994;343 (8894):1038-9.
47. Hamada H, Arinami T, Sodha S, Hamaguchi H, Kubo T. Mid trimester fetal sex determination from maternal peripheral blood by fluorescence in situ hybridization without enrichment of fetal cells. Prenat Diagn 1995,15:78-81.
48. Kao SM, Tang GC, Hsieh TT, Young KC, Wang HC, Pao CC. Analysis of peripheral blood of pregnant women for the presence of fetal Y chromosome specific ZFY gene deoxyribonucleic acid sequences. Am J Obstet Gynecol 1992 166:1013-9.
49. Simpson JL, Elias S. Isolating fetal erythroblasts from maternal blood with identification of fetal trisomy by fluorescent in situ hybridization. Prenat Diagn 1992;12:S34.
50. Elias S, Price J, Dockter M, Wachtel S, Tharapel A, Simpson JL. First trimester prenatal diagnosis of trisomy 21 in fetal cells from maternal blood. Lancet 1992;340:1033.
51. Thilaganathan B, Meher-Homji N, Nicolaïdes KH. Blood transferrin receptor expression in chromosally abnormal fetuses. Prenat Diagn 1995;15:282-4.
52. Lo YMD, Noakes L, Bowell PJ, Fleming KA, Wainscoat JS. Detection of fetal Rh D sequence from peripheral blood of sensitised Rh D negative pregnant women. Br J Haematol 1994;87:658-60.
53. Chua S, Wilkins T, Sargent I, Redman C. Trophoblast deportation in preeclampsic pregnancy. Br J Obstet Gynaecol 1991;98:973-9.
54. Schwinger E, Hillers M, Vosberg HP. No identification of Y chromosomal DNA in blood from pregnant women bearing a male fetus. Am J Hum Genet 1989;45:A 268.
55. Lo YMD, Patel P, Wainscoat JS, Sampietro M, Gillmer MDG, Fleming KA. Prenatal sex determination by DNA amplification from maternal peripheral blood. Lancet 1989;2:1363-5.
56. Bianchi DW, Mahr A, Zickwolf GK, Houseal T, Flint AF, Klinger KW. Detection of fetal cells with 47XY, +21 karyotype in maternal peripheral blood. Hum Genet 1992;90:368-70.
57. Büsch J, Huber P, Pflüger E, Miltenyi ST, Holtz J, Radbruch A. Enrichment of fetal cells from maternal blood by high gradient magnetic cell sorting (double MACS) for PCR based genetic analysis. Prenat Diagn 1994;14:1129-40.
58. Sekizawa A, Watanabe A, Kimura T, Saito H, Yanaihara T, Sato T. Prenatal diagnosis of fetal Rh D blood type using a single fetal nucleated erythrocyte from maternal blood. Obstet Gynecol 1996;87 (4):501-4.
59. Bhat MM, Bieber MM, Teng NNH. One step enrichment of nucleated red blood cells. J Immunol Meth 1993;158:277-80.
60. Holzgreve W, Ganshirt-Ahlert D, Dohr A, Helmer L, Miny P. Magnetically activated cell sorting for the isolation of fetal cells from maternal circulation. Prenat Diagn 1992;12:S 17.
61. Ganshirt-Alhert D, Burschyk M, Garritsen HSP. Magnetic cell sorting and the transferrin receptor as potential means of prenatal diagnosis from maternal blood. Am J Obstet Gynecol 1992;166:1350-5.
62. Van WiJk IJ, Van Vugt JM, Mulders MA, Konst AA, Weima SM, Oudejans CB. Enrichment of fetal trophoblast cells from maternal peripheral blood followed by detection of fetal deoxyribonudeic acid with a nested X/Y polymerase chain reaction. Am J Obstet Gynecol 1996;174 (3):871-8.
63. Durrant L, Mc Dowall K, Holmes R, Liu D. Non invasive prenatal diagnosis by isolation of both trophoblasts and fetal nucleated red blood cells from the peripheral blood of pregnant women. Br J Obstet Gynaecol 1996;103:219-22.
64. Wachtel S, Elias S, Price J. Fetal cells in the maternal circulation : isolation by multiparameter flow cytometry and confirmation by polymerase chain reaction. Hum Reprod 1991;6:1466-9.
65. Elias S, Simpson JL. Prenatal diagnosis of aneuploïdy using fetal cells isolated from maternal blood/University of Tennessee, Menphis experience. In : Simpson JL, Elias S (Eds). Fetal cells in maternal blood: Prospects for non invasive prenatal diagnosis, New York. New York Academy of sciences 1994;731:80-91.
66. Bianchi DW, Klinger KW, Vadnais TJ, Demaria MA, Shuber AP, Skoletsky J et al. Development of a model system to compare cell separation methods for the isolation of fetal cells from maternal blood. Prenat diagn 1996;16: 289-98.
67. Lo YMD, Morey AL, Wainscoat JS, Fleming KA. Culture of fetal erythroid cells from maternal peripheral blood. Lancet 1994;344:264-5.
68. Valerio D, Aiello R, Altieri V, Malato AP, Fortunato A, Canazio A. Culture of fetal erythroid progenitor cells from maternal blood for non invasive prenatal genetic diagnosis. Prenat Diagn 1996;16:1073-82.
69. Valerio D, Altieri V, Antonucci FR, Aiello R. Characterization of fetal haematopoietic progenitors circulating in maternal blood of seven aneuploid pregnancies. Prenat Diagn 1997;17 (12):1159-69.
70. Sekizawa A, Kimura T, Sasaki M, Nakamura S, Kobayashi R, Sato T. Prenatal diagnosis of Duchenne muscular dystrophy using a single fetal nucleated erythrocyte in maternal blood. Neurology 1996;46:1350-3.
71. Chueh J, Golbus MS. The search for fetal cells in the maternal circulation. J Perinat Med 1991;19/6:411-20.
72. Lo YMD, Patel P, Baignent CN. Prenatal sex determination from maternal peripheral blood using the polymerase chain reaction. Hum Genet 1993;90:483-8.
73. Holzgreve W, Ganshirt-Alhert D, Burschyk M, Horst J, Miny P, Gal A et al. Detection of fetal DNA in maternal blood by PCR. Lancet 1990;i:1220-1.
74. Lo YMD, Bowell PJ, Selinger M. Prenatal determination of fetal RhD status by analysis of peripheral blood of rhesus negative mothers. Lancet 1993;341:1147-8.
75. Geifman Holtzman O, Demaria M, Vadnaid TJ, Bernstein IM, Capeless EL, Bianchi DW. Determination of fetal rhesus D (Rh (D)) type by PCR amplification of fetal cells in flow sorted Rh (D) negative maternal blood. 1994 In : Zakut H. (Ed). 7th International Conference on Early Prenatal Diagnosis, Bologna : Monduzzi Editore, 41-5.
76. Geifman OH, Bernstein IM, Berry SM, Holtzman EJ, Vadnais TJ, Demaria MA et al. Fetal RhD genotyping in fetal cells flow sorted from maternal blood. Am J Obstet Gynecol 1996;174:818-22.
77. Camaschella C, Alfarano A, Gottardi E, Travi M, Primigari P, Caligaris-Cappio F et al. Prenatal diagnosis of fetal hemoglobin Lepore - Boston disease on maternal peripheral blood. Blood 1990;75:2102-6.
78. Hawes CS, Suskin HA, Kalionis B, Mueller UW, Casey G, Hall J et al. Detection of paternally inherated mutations for beta thalassemia in trophoblast Isolated from peripheral maternal blood. In : Simpson JL, Elias S (Eds). Fetal cells in maternal blood : Prospects for non invasive prenatal diagnosis, New York. New York Academy of sciences 1994;731:181-5.
79. Divane A, Carter NP, Spathas DH, Ferguson-Smith MA. Rapid prenatal diagnosis of aneuploidy from uncultured amniotic fluid cells using five colour fluorescence in situ hybridization. Prenat Diagn 1994;14:1061-9.
80. Chueh J, Golbus MS. Prenatal diagnosis using fetal cells in the maternal circulation. Semin Perinat 1990;14:471.
81. Björkvist AM, Slunga-Tatlberg A, Weissman M, Ylinen K, Knuutila S. Prenatal sex determination by in situ hybridization on fetal nucleated cells in maternal whole venous blood. Clin genet 1994;46:352-6.
82. Elias S, Price J, Klinger K. Prenatal diagnosis of aneuploïdy using fetal cells isolated from maternal blood. Am J Hum Genet 1992;51:A4.
83. Von Koskull, Gahmberg N. Fetal erythroblasts from maternal blood identified with 2,3- bisphosphoglycerate (BPG) and in situ hybridization (ISH) using Y specific probes. Prenat Diagn 1995;15:149-54.