Cultured rabbit renal proximal straight tubular cells are more susceptible to mercuric chloride than convoluted tubular cells

In Vitro and Molecular Toxicology: Journal of Basic and Applied Research

Volumn 11, Issue 2, 1998, Pages 133-138

  Trifillis, A ^a   Del Valle, P ^a   Cui, X ^a   Lipsky, M ^a   Ruegg, C ^b   Kane, A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b In Vitro Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN; MERCURIC CHLORIDE; PROPIDIUM IODIDE;

ANIMAL CELL; ARTICLE; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; EPITHELIUM CELL; KIDNEY CELL CULTURE; KIDNEY PROXIMAL TUBULE; MALE; MONOLAYER CULTURE; NEPHROTOXICITY; NONHUMAN; RABBIT; SPECTROFLUOROMETRY;

EID: 0031687405     PISSN: 10979336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. ALEO, M.D., and TAUB, M.L., (1992). Kostyniak PJ primary cultures of rabbit renal proximal tubule cells. III. Comparative cytotoxicity of inorganic and organic mercury. Toxicol. Appl. Pharmacol. 112, 310-317.
2. BARR, R.D., WOODGER, B.A., and REES, P.H. (1973). Levels of mercury in urine correlated with the use of skin lightening creams. Am. J. Clin. Pathol. 59, 36-40.
3. BLAIS, A., MORVAN-BALEYNAUD, J., FRIEDLANDER, G., and LE GRIMEELLAC, C. (1993) Primary culture of rabbit proximal tubules as a cellular model to study nephrotoxicity of xenobiotics. Kidney Int. 44, 13-18.
4. BOOGAARD, P.J., NAGELKERKE, J.F., and MULDER, G.J. (1990). Renal proximal tubular cells in suspension or in primary culture as in vitro models to study nephrotoxicity. Chem. Biol. Interact. 76, 251-292.
5. CHUNG, S.D., ALAVI, N., and LIVINGSTON, D., (1982). Characterization of primary rabbit kidney cultures that express proximal tubule functions in a hormonally defined medium. J. Cell Biol. 95, 118-126.
6. FLAMENBAUM, W., (1973). Pathophysiology of acute renal failure. Arch. Intern. Med. 131, 911-928.
7. HAAGSMA, B.H., and POUND, A.W. (1979). Mercuric chloride-induced renal tubular necrosis in the rat. Brit. J. Exp. Pathol. 60, 341-352.
8. HOOK, J.B., and HEWITT, W.R. (1986). Toxic responses of the kidney, in Casarett and Doull's Toxicology: The Basic Science of Poisons, 3rd ed. C.D. Klaassen, M.O. Amdur and J. Doull. (eds.) MacMillan: NY, pp. 319-329.
9. McDOWELL, E.M., NAGLE, R.B., ZALME, R.C., McNEIL, J.S., FLAMENBAUM, W., and TRUMP, B.F. (1976). Studies on the pathophysiology of acute renal failure. I. Correlation of ultrastructure and function in the proximal tubule of the rat following administration of mercuric chloride. Virchows Arch. B. 22, 173-196.
10. NIEMENIN, A.L., GORES, G.J., DAWSON, T.L., HERMAN, B., and LEMASTERS, J.J. (1990). Toxic injury from mercuric chloride in rat hepatocytes. J. Biol. Chem. 265, 2399-2408.
11. PHELPS, J.S., GANDOLFI, A.J., BRENDEL, K., and DORR, R.T. (1987). Cisplatin nephrotoxicity: In vitro studies with precision-cut rabbit renal cortical slices. Toxicol. Appl. Pharmacol. 90, 501-512.
12. RUEGG, C.E., GANDOLFI, A.J., NAGLE, R.B., and BRENDELL, K. (1987a). Differential patterns of injury to the proximal tubule of renal cortical slices following in vitro exposure to mercuric chloride, potassium dichromate, or hypoxic conditions. Toxicol. Appl. Pharmacol. 90, 261-273.
13. RUEGG, C.E., GANDOLFI, A.J., NAGLE, R.B., KRUMDIECK, C.L., and BRENDEL, K. (1987b). Preparation of positional renal slices for study of cell-specific toxicity. J. Pharmacol. Methods. 17, 111-123.
14. RUEGG, C.E., and MANDEL, L.J. (1990a). Bulk isolation of renal PCT and PST. I. Glucose-dependent metabolic differences. Am. J. Physiol. 259, F164-F175.
15. RUEGG, C.E., and MANDEL, L.J. (1990b). Bulk osolation of renal PCT and PST. II. Differential responses to anoxia or hypoxia. Am. J. Physiol. 259, F176-F185.
16. SIEGEL, F.L., and BULGER, R.E. (1975). Scanning and transmission electron microscopy of mercuric chloride induced acute tubular necrosis in the rat kidney. Virchows Arch. B. 18, 243-262.
17. TRIFILLIS, A.L., KAHNG, M.W., and TRUMP, B.F. (1981). Metabolic studies of HgCl2-induced acute renal failure in the rat. Exp. Mol. Pathol. 35, 1-13.
18. WOLFGANG, G.H., GANDOLFI, A.J., NAGLE, R.B., BRENDEL, K., and STEVENS, J.L. (1990). Assessment of S-(1,2-dichlorovinyl)-L-cysteine induced toxic events in rabbit renal cortical slices. Biochemical and histological evaluation of uptake, covalent binding, and toxicity. Chem. Biol. Interact. 75, 153-170.
19. ZALUPS, R.K., and BARFUSS, D.W. (1993). Transport and toxicity of methylmercury along the proximal tubule of the rabbit. Toxicol. Appl. Pharmacol. 121, 175-185.