An approach for dose finding of drugs in infants: Sedation by midazolam studied using the continual reassessment method

British Journal of Clinical Pharmacology

Volumn 46, Issue 4, 1998, Pages 395-401

  Fabre, Emmanuelle ^a   Chevret, Sylvie ^b   Piechaud, Jean François ^c   Rey, Elisabeth ^a   Vauzelle Kervroedan, Françoise ^a   D'Athis, Phillippe ^d   Olive, Georges ^a   Pons, Gérard ^a  

^a HÔPITAL SAINT VINCENT DE PAUL   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d HÔPITAL DU BOCAGE   (France)

Author keywords

Cardiac catheterization; Infants; Midazolam; Sedation

Indexed keywords

MIDAZOLAM;

AREA UNDER THE CURVE; ARTICLE; BAYES THEOREM; CLINICAL TRIAL; CONTROLLED STUDY; DOSE CALCULATION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG HALF LIFE; DRUG TOLERABILITY; HEART CATHETERIZATION; HUMAN; INFANT; METHODOLOGY; PHASE 2 CLINICAL TRIAL; PRESCHOOL CHILD; PRIORITY JOURNAL; RECTAL DRUG ADMINISTRATION; SEDATION;

ADMINISTRATION, RECTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; HEART CATHETERIZATION; HUMANS; HYPNOTICS AND SEDATIVES; INFANT; MIDAZOLAM;

EID: 0031687362     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1998.00788.x     Document Type: Article

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