No evidence for linkage of the CHRNA7 gene region in Canadian schizophrenia families

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 81, Issue 5, 1998, Pages 361-363

  Neves Pereira, M ^a   Bassett, A S ^b   Honer, W G ^c   Lang, D ^a   King, N A ^a   Kennedy, J L ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Alpha 7 neuronal nicotinic acetylcholine receptor; Genetics; Linkage; Schizophrenia

Indexed keywords

NICOTINIC RECEPTOR;

ARTICLE; CANADA; CLINICAL ARTICLE; COMORBIDITY; GENETIC LINKAGE; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; HUMAN; PREVALENCE; PRIORITY JOURNAL; SCHIZOPHRENIA; SENSORY DYSFUNCTION;

CHROMOSOMES, HUMAN, PAIR 15; FEMALE; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); MALE; RECEPTORS, NICOTINIC; SCHIZOPHRENIA;

EID: 0031687338     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19980907)81:5<361::AID-AJMG3>3.0.CO;2-W     Document Type: Article

References (11)

1. Bassett AS, Honer WG (1994): Evidence for anticipation in schizophrenia. Am J Hum Genet 54:864-870.
2. Bassett AS, Collins EJ, Nuttall SE, Honer WG (1993): Positive and negative symptoms in families with schizophrenia. Schizophr Res 11:9-19.
3. Freedman R, Coon H, MylesWorsley M, OrrUrtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, Young DA, Breese CR, Adams C, Patterson D, Adler LE, Kruglyak L, Leonard S, Byerley W (1997): Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci USA 94:587-592.
4. Greenberg DA, Hodge SE, Vieland VJ, Spence MA (1995): Affecteds-only linkage methods are not a panacea. Am J Hum Genet 58:892-895.
5. King N, Basssett AS, Honer WG, Masellis M, Kennedy JL (1997): Absence of linkage for schizophrenia on the short arm of chromosome 5 in multiplex Canadian families. Am J Med Genet 74:472-474.
6. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES (1996): Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 58:1347-1363.
7. O'Malley MP, Bassett AS, Honer WG, Kennedy JL, King N, Berg D (1996): Linkage analysis between schizophrenia and the Darier's disease region on 12q. Psychiatr Genet 6:187-190.
8. Petronis A, Bassett AS, Honer WG, Vincent JB, Tatuch Y, Sasaki T, Ying D-J, Klempan TA, Kennedy JL (1996): Search for unstable DNA in schizophrenia families with evidence for genetic anticipation. Am J Hum Genet 59:905-911.
9. Risch N, Merikangas K (1996): The future of genetic studies of complex human diseases. Science 273:1516-1517.
10. Sidenberg DG, Bassett AS, Demchyshyn L, Niznik HB, Macciardi F, Kamble AB, Honer WG, Kennedy JL (1993): New polymorphism for the human serotonin ID receptor variant (5HTIDβ) not linked to schizophrenia in five Canadian pedigrees. Hum Hered 43:315-318.
11. Vicente AM, Macciardi F, Verga M, Bassett AS, Honer WG, Bean G, Kennedy JL (1997): NCAM and schizophrenia: Genetic studies. Mol Psychiatry 2:65-69.