Adverse effects of opioid agonists and agonist-antagonists in anaesthesia

Drug Safety

Volumn 19, Issue 3, 1998, Pages 173-189

  Bowdle, T Andrew ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALFENTANIL; BENZODIAZEPINE; BUPRENORPHINE; BUTORPHANOL; DEXTROMETHORPHAN; FENTANYL; HISTAMINE; KAPPA OPIATE RECEPTOR; MONOAMINE OXIDASE INHIBITOR; MORPHINE; MORPHINE 6 GLUCURONIDE; NORPETHIDINE; OPIATE AGONIST; OPIATE ANTAGONIST; OPIATE RECEPTOR; PENTAZOCINE; PETHIDINE; SEROTONIN UPTAKE INHIBITOR; TRAMADOL;

ANALGESIA; ANESTHESIA; ARTICLE; ASYSTOLE; BLOOD PRESSURE; BRADYCARDIA; BRAIN BLOOD FLOW; CARDIOVASCULAR SYSTEM; DRUG ABSORPTION; DRUG POTENCY; GASTROINTESTINAL SYMPTOM; HEART RATE; HISTAMINE RELEASE; HUMAN; HYPOTENSION; INTRACRANIAL PRESSURE; INTRANASAL DRUG ADMINISTRATION; INTRASPINAL DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MUSCLE RIGIDITY; MYOCARDIAL DISEASE; MYOCLONUS; NAUSEA; NEUROTOXICITY; PRIORITY JOURNAL; RESPIRATION DEPRESSION; SEIZURE; SEROTONIN SYNDROME; SPINAL ANESTHESIA; SYSTEMIC VASCULAR RESISTANCE; TRANSDERMAL DRUG ADMINISTRATION; VOMITING;

ANALGESICS, OPIOID; ANESTHESIA; ANIMALS; BENZODIAZEPINES; CARDIOVASCULAR SYSTEM; CEREBROVASCULAR CIRCULATION; DRUG INTERACTIONS; HUMANS; INTRACRANIAL PRESSURE; MUSCLE RIGIDITY; NAUSEA; RECEPTORS, OPIOID; RESPIRATION; SEROTONIN SYNDROME; SPINAL CORD; VOMITING;

EID: 0031687335     PISSN: 01145916     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002018-199819030-00002     Document Type: Article

References (104)

1. Hayashi Y, Maze M. Drugs affecting adrenoceptors alpha-2 agonists. In: Bowdle T, Horita A, Kharaseh E, editors. The pharmacologic basis of anesthesiology. New York: Churchill Livingstone, 1994; 607-779
2. Bowerson SS, Gadbois T, Singh T, et al. Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-11, produces spinal antinociception in rat models of acute, persistent and neurophatic pain. J Pharmacol Exp Ther 1996; 279: 1243-9
3. Pasternak GW, Basic pharmacology of opioids. In: Bowdle T, Horita A, Kharasch E, editors. The pharmacologic basis of anesthesiology. New York: Churchill Livingstone, 1994: 19-36
4. Pasternak GW, Standifer KM. Mapping opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology. Trends Pharmacol Sci 1995; 16: 344-50
5. Rossi GC, Pan Y-X, Brown GP, et al. Antisense mapping the MOR-1 opioid receptor: evidence for alternative splicing and a novel morphine-6beta-glucuronide receptor. FEBS Lett 1995; 369: 192-6
6. Rossi GC, Brouw GP, Leventhal L, et al. Novel receptor mechanisms for heroin and morphine-6beta-glucuronide analgesia. Neurosci Lett 1996; 216: 1-4
7. Henderson G, McKnight AT. The orphan opioid receptor and its endogenous ligand-nociceptin/orphanin FQ. Trends Pharmacol Sci 1997; 18: 293-300
8. Stein C. Peripheral mechanisms of opioid analgesia. Anesth Analg 1993; 76: 182-91
9. Kolesnikov YA, Jain S, Wilson R, et al. Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance. J Pharmacol Exp Ther 1996; 279: 502-6
10. Khoury GF, Chen ACN, Garland DE, et al. Intraarticular morphine, bupivacaine, and morphine/bupivacaine for pain control after knee videoarthroscopy. Anesthesiology 1992; 77: 263-6
11. Dobreni K, Makman MH, Stefano GB. Occurrence of the opiate alkaloid-sensitive mu receptor in mammalian microglia, astrocytes and Kupffer cells. Brain Res 1995; 686: 239-48
12. Stefano GB, Scharrer B. Endogenous morphine and related opiates, a new class of chemical messengers. Adv Neuroimmunol 1994; 4: 57-67
13. Kodaira H, Spector S. Transformation of thebaine to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes. Proc Natl Acad Sci USA 1988; 85: 1267-71
14. Stefano GB, Digenis A, Spector S, et al. Opiate-like substances in an invertebrate, an opiate receptor on invertebrate and human immunocytes, and a role in immunosuppression. Proc Natl Acad Sci USA 1993; 90: 11099-103
15. Freye E, Hartung E, Schenk GK, Bremazocine: an opiate that induces sedation and analgesia without respiratory depression. Anesth Analg 1983; 62: 483-8
16. Castillo R, Kissin I, Bradley E. Selective kappa opioid agonist for spinal analgesia without the risk of respiratory depression. Anesth Analg 1986; 65: 350-4
17. Millan MJ. Kappa-opioid receptors and analgesia. Trends Pharmacol Sci 1990; 11: 70-6
18. Bowdle TA, Nelson WL. Partial agonist, mixed agonist-antagonist, and antagonist opioids. In: Bowdle T, Horita A, Kharasch E, editors. The pharmacologic basis of anesthesiology. New York: Churchill Livingstone, 1994
19. Keats AS, Telford T, Studies of analgesic drugs X, Respiratory effects of narcotic antagonists. J Pharmacol Exp Ther 1966; 112: 126-32
20. Romagnoli A, Keats AS. Ceiling effect for respiratory depression by nalbuphine. Clin Pharmacol Ther 1980; 27: 478-85
21. Romagnoli A, Keats AS. Ceiling respiratory depression by dezocine. Clin Pharmacol Ther 1984; 35: 367-73
22. Gal TJ, DiFazio CA. Ventilatory and analgesic effects of dezocine in humans. Anesthesiology 1984; 61: 716-22
23. Nagashima H, Karamanian A, Malovany R, et al. Respiratory and circulatory effects of intravenous butorphanol and morphine. Clin Pharmacol Ther 1976; 19: 738-45
24. Zucker JR, Neuenfeldt T, Freund PR. Respiratory effects of nalbuphine and butorphanol in anesthetized patients. Anesth Analg 1987; 66: 879-81
25. Pick CG, Peter Y, Schreiber S, et al. Pharmacological characterization of buprenorphine, a mixed agonist-antagonist with kappa; analgesia. Brain Res 1997; 744: 41-6
26. Dum JE, Herz A. In vivo receptor binding of the opiate partial agonist, buprenorphine, correlated with its agonistic and antagonistic actions. Br J Pharmacol 1981; 74: 627-33
27. Orwin JM. The effect of doxapram on buprenorphine induced respiratory depression. Acta Anaesthsiol Belg 1977; 2: 93-105
28. Gal TJ. Naloxone reversal of buprenorphine-induced respiratory-depression. Clin Pharmacol Ther 1989; 45: 66-71
29. Rovati GE, Nicosia S. Lower efficacy: interaction with an inhibitory receptor or partial agonism? Trends Pharmacol Sci 1994; 15: 140-1
30. Pedersen JE, Chraemmer-Jorgensen B, Schmidt JF, et al. Naloxone - a strong analgesic in combination with high-dose buprenorphine? Br J Anaesth 1985; 57: 1045-6
31. Hoskin PJ, Hanks GW. Opioid agonist-antagonist drugs in acute and chronic pain states. Drugs 1991; 41: 326-44
32. Yeadon M, Kitchen I. Comparative binding of mu and delta selective ligands in whole brain and pons/medulla homogenates from rat: affinity profiles of fentanyl derivatives. Neuropharmacology 1988; 27: 345-8
33. Clark NJ, Meuleman T, Liu W, et al. Comparison of sufentanilN20 and fentanyl-N20 in patients without cardiac disease undergoing general surgery. Anesthesiology 1987; 66: 130-5
34. Bailey PL, Streisand JB, East KA, et al. Differences in magnitude and duration of opioid-induced respiratory depression and analgesia with fentanyl and sufentanil. Anesth Analg 1990; 70: 8-15
35. Yeadon M, Kitchen I. Multiple opioid receptors mediate the respiratory depressant effects of fentany-like drugs in the rat. Gen Pharmacol 1990; 21: 655-64
36. Jones JG. The respiratory effects of meptazinol. Postgrad Med J 1983; 59 (Suppl. 1): 72-7
37. Seitz W, Lubbe N, Fritz K, et al. Effects of tramadol on respiratory CO2 response and mouth occlusion pressure. Anaesthesist 1985; 34: 241-6
38. Vickers MD, O'Flaherty D, Szekely SM, et al. Tramadol: pain relief by an opioid without depression of respiration. Anaesthesia 1992: 291-6
39. Houmes RM, Voets MA, Verkaaik A, et al. Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression. Anesth Analg 1992; 74: 510-4
40. Hughes J, Kosterlitz AW, Smith TW. The distribution of methionine-enkephalin and leucine-enkephalin in the brain and peripheral tissues. Br J Pharmacol 1977; 61: 639-47
41. Sapru HN, Willette RN, Krieger AJ. Stimulation of pulmonary J receptors by an enkephalin-analog. J Pharmacol Exp Ther 1981; 217: 228-34
42. Ohtani M, Kotaki H, Nishitateno K, et al. Kinetics of respiratory depression in rats induced by buprenorphine and its metabolite, norbuprenorphine. J Pharmacol Exp Ther 1997; 281: 428-33
43. Flacke JW, Flacke WE, Bloor BC, et al. Histamine release by four narcotics: a double-blind study in humans. Anesth Analg 1987; 66: 723-30
44. Freye E. Cardiovascular effects of high dosages of fentanyl, meperidine, and naloxone in dogs. Anesth Analg 1974; 53: 40-7
45. Hall RI, Murphy MR, Szlam F, et al. Dezocine-MAC reduction and evidence for myocardial depression in the presence of enflurane. Anesth Analg 1987; 66: 1169-74
46. Buffington CW. Hemodynamic determinants of ischemic myocardial dysfunction in the presence of coronary stenosis in dogs. Anesthesiology 1985; 63: 651-62
47. Jaffe JH, Martin WR. Narcotic analgesics and antagonists. In: Goodman L, Gilman A, Koelle G, editors. The pharmacological basis of therapeutics. 5th ed. New York: MacMillan, 1975: 245-83
48. Flacke JW, Davis LJ, Flacke WE, et al. Effects of fentanyl and diazepam in dogs deprived of autonomic tone. Anesth Analg 1985; 64: 1053-9
49. Flacke JW, Flacke WE, Bloor BC, et al. Effects of fentanyl, naloxone and clonidine on hemodynamics and plasma catecholamine levels in dogs. Anesth Analg 1983; 62: 305-13
50. Tomicheck RC, Rosow CE, Philbin DM, et al. Diazepamfentanyl interaction-hemodynamic and hormonal effects in coronary artery surgery. Anesth Analg 1983; 62: 881-4
51. Thomson IR, Putnins CL, Friesen RM. Hyperdynamic cardiovascular responses to anesthetic induction with high-dose fentanyl. Anesth Analg 1986; 65: 91-5
52. Janssen PAJ. The past, present and future of opioid analgesics in anesthesia. In: Estafanous F, ed. Opioids in anesthesia II. Boston: Butterworth-Heinemann, 1991: xvi
53. Benthuysen JL, Smith NT, Sanford TJ, et al. Physiology of alfentanil-induced rigidity. Anesthesiology 1986; 64: 440-6
54. Weinger MB, Segal IS, Maze M. Dexmedetomidine, acting through central alpha-2 adrenoceptors, prevents opiate-induced muscle rigidity in the rat. Anesthesiology 1989; 71: 242-9
55. Weinger MB, Chen D-Y, Lin T, et al. A role for CNS alpha-2 adrenergic receptors in opiate-induced muscle rigidity in the rat. Brain Res 1995; 669: 10-8
56. Vankova ME, Weinger MB, Chen D-Y, et al. Role of central mu, delta-1, and kappa-1 opioid receptors in opioid-induced muscle rigidity in the rat. Anesthesiology 1996; 85: 574-83
57. Weinger MB, Cline EJ, Smith NT, et al. Localization of brainstem sites which mediate alfentanil-induced muscle rigidity in the rat. Pharmacol Biochem Behav 1988; 29: 573-80
58. Bowdle TA, Rook GA. Postoperative myoclonus and rigidity after anesthesia with opioids. Anesth Analg 1994; 78: 783-6
59. Smith NT, Benthuysen JL, Bickford RG, et al. Seizures during opioid anesthetic induction-are they opioid-induced rigidity? Anesthesiology 1989; 71: 852-62
60. Bowdle TA. Myoclonus following sufentanil without EEG seizure activity. Anesthesiology 1987; 67: 593-5
61. Tempelhoff R, Modica PA, Bernardo KL, et al. Fentanyl-induced electrocorticographic seizures in patients with complex partial epilepsy. J Neurosurg 1992; 77: 201-8
62. Cascino GD, So EL, Sharbrough FW, et al. Alfentanil-induced epileptiform activity in patients with partial epilepsy. J Clin Neurophysiol 1993; 10: 520-5
63. Armstrong PJ, Bersten A. Normeperidine toxicity. Anesth Analg 1986; 65: 536-8
64. Milde LN, Milde JH, Gallagher WJ. Effects of sufentanil on cerebral circulation and metabolism in dogs. Anesth Analg 1990; 70: 138-46
65. Artru AA. Effects of fentanyl, sufentanil, and alfentanil on epileptiform EEG activity, cerebral blood flow, and intracranial pressure. In: Hines R, Bowdle TA, editors. Anesthesiology clinics of North America annual of anesthetic pharmacology. Philadelphia: WB Saunders, 1997: 117-54
66. Wahl M. Effects of enkephalins, morphine and naloxone on pial arteries during perivascular microapplication. J Cereb Blood Flow Metab 1985; 5: 451-7
67. Radnay PA, Brodman E, Mankikar D, et al. The effect of equianalgesic doses of fentanyl, morphine, meperidine and pentazocine on common bile duct pressure. Anaesthesist 1980; 29: 26-9
68. Jones RM, Detmer M, Hill AB, et al. Incidence of choledochoduodenal sphincter spasm during fentanyl-supplemented anesthesia. Anesth Analg 1981; 60: 638-40
69. Radnay PA, Duncalf D, Novakovic M, et al. Common bile duct pressure changes after fentanyl, morphine, meperidine, butorphanol, and naloxone. Anesth Analg 1984; 63: 441-4
70. McCammon RL, Stoelting RK, Madura JA. Effects of butorphanol, nalbuphine, and fentanyl on intrabiliary tract dynamics. Anesth Analg 1984; 63: 139-42
71. Economou G, Ward-McQuaid JN. A cross-over comparison of the effect of morphine, pethidine, pentazocine, and phenazocine on biliary pressure. Gut 1971; 12: 218-21
72. Staritz M, Poralla T, Manns M, et al. Effect of modern analgesic drugs (tramadol, pentazocine, and buprenorphine) on the bile duct sphineter in man. Gut 1986; 27: 567-9
73. Watcha M, While PF. Postoperative nausea and vomiting: its etiology, treatment and prevention. Anesthesiology 1992; 77: 162-84
74. Costello DJ, Borison HL. Naloxone antagonizes narcotic self-blockade of emesis in the cat. J Pharmacol Exp Ther 1977; 203: 222-30
75. Longnecker DE, Grazis P, Eggers GWN. Naloxone antagonism of morphine induced respiratory depression. Anesth Analg 1973; 52: 447-52
76. Yaksh TL, Collins JG. Studies in annuals should precede human use of spinally administered drugs. Anesthesiology 1989; 70: 4-6
77. Sandler AN. Clinical pharmacology and applications of spinal opioids. In: Bowdle TA, Horita A, Kharasch ED, editors. The pharmacologic basis of anesthesiology New York: Churchill Livingstone, 1994: 149-78
78. Sjostrom S, Tamsen A, Persson MP, et al. Pharmacokinetics of intrathecal morphine and meperidine in humans. Anesthesiology 1987; 67: 889-95
79. Loper KA, Ready B, Downey M, et al. Epidural and intravenous fentanyl infusions are clinically equivalent after knee surgery. Anesth Analg 1990; 70: 72-5
80. Camann WR, Loferski BL, Fanciullo GJ, et al. Does epidural administration of butorphanol offer any clinical advantage over the intravenous route? Anesthesiology 1992; 76: 216-20
81. Chaney M. Side effects of intrathecal and epidural opioids. Can J Anaesth 1995; 891-903
82. Sandler AN, Stringer D, Panos L, et al. A randomized, double-blind comparison of lumbar epidural and intravenous fentanyl infusions for post-thoracotomy pain relief: analgesic, pharmacokinetic and respiratory effects. Anesthesiology 1992; 77: 626-34
83. James CF. Recurrence of herpes simplex virus blepharitis after cesarean section and epidural morphine. Anesth Analg 1996; 82: 1094-6
84. Kavee EH, Ramanathan S. The hypothermic action of epidural and subarachnoid morphine in parturients. Region Anesth 1991; 16: 325-8
85. Sevarino FB, Johnson MD, Lema MJ, et al. The effect of epidural sufentanil on shivering and body temperature in the parturient. Anesth Analg 1989; 68: 530-3
86. Bodner RA, Lynch T, Lewis L, et al. Serotonin syndrome. Neurology 1995; 45: 219-23
87. Kam PCA, Chang GWM. Selective serotonin reuptake inhibitors: Pharmacology and clinical implications in anaesthesia and cinical care medicine. Anaesthesia 1997; 52: 982-8
88. Mitchell RS. Fatal toxic encephalitis occurring during iproniazid therapy in pulmonary tuberculosis. Ann Intern Med 1955; 148: 417-24
89. Sternbach H. The serotonin syndrome. Am J Psychiatry 1991; 148: 705-13
90. Rivers N, Homer B. Possible lethal interaction between Nardil and dextromethorphan. Can Med Assoc J 1970; 103: 85
91. Hansen TE, Dieter K, Keepers GA. Interaction of flouxetine and pentazocine. Am J Psychiatry 1990; 147: 949-50
92. Sinatra RS, Scrameik JL. Tramadol: its use in pain management. In: Hines R, Bowdle TA, editors. Anesthesiology clinics of North America annual of anesthetic pharmacology. Philadelphia: WB Saunders, 1998; 53-69
93. Amrein R, Guntert TW, Dingemanse J, et al. Interaction of moclobemide with concomitantly administered medication: evidence from pharmacological and clinical studies. Psychopharmacology 1992; 106: S24-31
94. Sternberg TL. All monoamine oxidase inhibitors are not equal. Anesth Analg 1997; 84: 938
95. Lee CR, McTavish D, Sorkin EM. Tramadol: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs 1993; 313-340
96. Raffa RB, Friderichs E, Reimann W. et al. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic. J Pharmacol Exp Ther 1992; 260: 275-85
97. Bowdle TA, Ward RJ. Induction of anesthesia with small doses ol sufentanil or fentanyl: dose versus EEG response, speed of onset and thiopental requirement. Anesthesiology 1989; 70: 26-30
98. Vinik HR. Intravenous anaesthetic drug interactions: practical applications. Eur J Anaesthesiol 1995; 12 Suppl. 12: 13-9
99. Vinik HR, Bradley EL, Kissin I. Midazolam-alfentanil synergism for anesthetic induction in patients. Anesth Analg 1989; 69: 213-7
100. Bailey PL, Pace NL, Ashburn MA, et al. Frequent hypoxemia and apnea after sedation with midazolam and fentanyl. Anesthesiology 1990; 73: 826-30
101. Jeal W, Benfield P. Transdermal fentanyl: a review of its pharmacological properties and therapeutic efficacy in pain control. Drugs 1997; 53: 109-38
102. Bowdle TA, Galer BS. Agonist-antagonist and partial agonist opioids: pharmacologic mechanisms and clinical application in the treatment of headache. Headache Q 1993; 4: 322-36
103. Preston KL, Sullivan JT, Testa M, et al. Psychopharmacology and abuse potential of transnasal butorphanol. Drug Alcohol Depend 1994; 35: 159-67
104. Rosow CE, Connors PM, Hennessy D, et al. Bioavailability of nasal butorphanol. Anesthesiology 1996; 85: A314