In vitro toxicity of zamifenacin (UK-76,654) and metabolites in primary hepatocyte cultures

Xenobiotica

Volumn 28, Issue 9, 1998, Pages 895-908

  Amacher, D E ^a   Fasulo, L M ^a   Charuel, C ^a   Comby, P ^a   Beaumont, K ^b  

^a PFIZER INC   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; MUSCARINIC M3 RECEPTOR ANTAGONIST; UK 80178; UK 80528; UK 82201; UNCLASSIFIED DRUG; ZAMIFENACIN;

ANIMAL CELL; ARTICLE; DOG; DRUG CYTOTOXICITY; DRUG METABOLISM; DRUG TRANSFORMATION; DRUG UPTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IRRITABLE COLON; LIVER CELL CULTURE; LIVER TOXICITY; MALE; NONHUMAN; TOXICITY TESTING;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CATECHOLS; CELLS, CULTURED; DIOXOLES; DOGS; HALF-LIFE; KINETICS; L-LACTATE DEHYDROGENASE; LIVER; MACACA FASCICULARIS; MALE; METHYLATION; MUSCARINIC ANTAGONISTS; NEUTRAL RED; PIPERIDINES; RATS;

ANIMALIA; CANIS FAMILIARIS;

EID: 0031685498     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982598239137     Document Type: Article

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