Immunophenotype and clinical characteristics of CD45-negative and CD45-positive childhood acute lymphoblastic leukemia

Annals of Hematology

Volumn 77, Issue 3, 1998, Pages 107-114

  Ratei, R ^a   Sperling, C ^a   Karawajew, L ^a   Schott, G ^a   Schrappe, M ^b   Harbott, J ^c   Riehm, H ^b   Ludwig, W D ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

CD45; Childhood ALL; Immunophenotype; Leukocyte common antigen

Indexed keywords

CD22 ANTIGEN; CD24 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; FLUORESCEIN ISOTHIOCYANATE; PROPIDIUM IODIDE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTIGEN EXPRESSION; ARTICLE; B CELL LEUKEMIA; BLOOD SAMPLING; BONE MARROW; CELL CYCLE; CELL SUBPOPULATION; CHILDHOOD LEUKEMIA; CLINICAL FEATURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LEUKEMIA CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; T CELL LEUKEMIA;

ANTIGENS, CD45; ANTINEOPLASTIC AGENTS, HORMONAL; CELL LINEAGE; CHILD; DNA, NEOPLASM; HUMANS; IMMUNOPHENOTYPING; KARYOTYPING; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; PREDNISONE; TREATMENT OUTCOME;

EID: 0031685495     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002770050424     Document Type: Article

References (27)

1. Behm FG, Raimondi SC, Schell MS, Look AT, Rivera GK, Pui CH (1992) Lack of CD45 antigen on blast cells in childhood acute lymphoblastic leukemia is associated with chromosomal hyperdiploidy and other favorable prognostic features. Blood 79 : 1011-1016
2. Béné MC, Castoldi G, Knapp W, Ludwig W-D, Matutes E, Orfao A, van't-Veer MB (1995) Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL). Leukemia 9 : 1783-1786
3. Borowitz MJ, Shuster J, Carroll AJ, Nash M, Look T, Camitta B, Mahoney D, Lauer SJ, Pulle DJ (1997) Prognostic significance of fluorescence intensity of surface marker expression in childhood B-precursor acute lymphoblastic leukemia. A Pediatric Oncology Group study. Blood 89 : 3960-3966
4. Caldwell CW, Patterson WP, Hakami N (1993) CD45 expression and prognosis in acute lymphoblastic leukemia. Blood 81 : 562-563
5. Craig W, Poppema S, Little M-T, Dragowska W, Lansdorp P (1994) CD45 isoform expression on human haematopoietic cells at different stages of development. Br J Haematol 88 : 24-30
6. de Mascarel A, Merlio JP, Coindre JM, Goussot JF, Broustet A (1989) Gastric large cell lymphoma expressing cytokeratin but no leucocyte common antigen. Am J Clin Pathol 91 : 478-482
7. Domiati SR, Ogle EW, Justement LB (1993) Administration of anti-CD45 mAB specific for a B-cell restricted epitope abrogates the B cell response to a T-independent antigen in vivo. J Immunol 151 : 5936-5947
8. Drexler HG., Thiel E, Ludwig W-D (1991) Review of the incidence and clinical relevance of myeloid antigen-positive acute lymphoblastic leukemia. Leukemia 5 : 637-645
9. Fischer EH, Charbonneau H, Tonks NK (1991) Protein tyrosine phosphatases: a diverse family of intracellular and transmemhrane enzymes. Science 253 : 401-406
10. Hathcock KS, Laszlo G, Dickler HB, Sharrow SO, Johnson P, Trowbridge IS, Hodes RJ (1992) Expression of variable exon A-.B-, and C-specific CD45 determinants on peripheral and thymic T-cell populations. J Immunol 148 : 19-28
11. Justement LB, Cambell KS, Chien NC, Cambier JC (1991) Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45. Science 252 : 1839-1842
12. Justement LB, Brown VK, Lin J (1994) Regulation of B-cell activation by CD45 : a question of mechanism. Immunol Today 15 : 399-406
13. Kato T, Kokuho T, Tamura T, Nariuchi H (1994) Mechanism of T cell contact-dependent B cell activation. J Immunol 152 : 2130-2138
14. lo population in chronic myeloid leukemia: an analysis using interphase fluorescence in situ hybridisation. Blood 86 : 737-743
15. Klaus SJ, Sidorenko SP, Clark EA (1996) CD45 ligution induces cell death in T and B lymphocytes. J Immunol 156 : 2743-2753
16. Lamkin T, Brooks J, Annett G, Roberts W, Weinberg K (1994) Immunophenotypic differences between putative hematopoietic stem cells and childhood B-cell precursor acute lymphoblastic leukemia cells. Leukemia 8 : 1871-1878
17. Ludwig WD, Bartram C, Ritler J, Raghavachar A, Hiddemann W, Heil G, Harbott J, Seibt-Jung H, Teichmann J, Riehm H (1988) Ambiguous phenotypes and genotypes in 16 children with acute leukemia as characterized by multiparameter analysis. Blood 71 : 1518-1528
18. Ludwig WD, Rhagavachar A, Thiel E (1994) Immunophenotypic classification of acute lymphoblastic leukemia. Baillieres Clin Haematol 7 : 235-262
19. Ludwig WD, Rieder H, Bartram CR, Heinze B, Schwartz S, Gassmann W, Löffler H, Hossfeld D, Heil G, Handt S, Heyll A, Diedrich H, Fischer K, Weiss A, Völkers B, Aydemir Ü, Fonatsch C, Gökbuget N, Thiel E, Hoelzer D (1998) Immunophenotypic and genotypic features, clinical characteristics, and treatment outcome of adult pro-B acute lymphoblastic leukemia: results of the German multicenter trials GMALL 03/87 and 04/89. Blood (in press)
20. Melkerson-Watson LJ, Waldmann ME, Gunter AD, Zaroukian MH, Esselman WJ (1994) Elevation of lymphocyte CD45 protein tyrosine phosphatase activity during mitosis. J Immunol 153 : 10004-10013
21. Ralph SJ, Thomas ML, Morton CC, Trowbridge IS (1987) Structural variants of human T200 glycoprotein (leucocyte-common-antigen). EMBO J 6 : 1251-1257
22. Rothe G, Schmitz G, for the Working Group on Flow Cytometry and Image Analysis. Members of the editorial committee: Adorf D, Barlage S, Gramatzki, Hanenberg H, Höffkes HG, Janossy G, Knüchel R, Ludwig W-D, Nebe T, Nerl C, Orfao A, Serke S, Sonnen R, Tichelli A, Wörmann B (1996) Consensus protocol for the flow cytometric immunophenotyping of hematopoietic malignancies. Leukemia 10 : 877-895
23. Schrappe M, Reiter A, Sauter S, Ludwig W-D, Wörmann B, Harbott J, Bender-Götze C, Dörffel W, Frey E, Havers W, Henze G, Kühl J, Richter R, Ritter J, Treuner J, Zintl F, Odenwald E, Welte K, Lampert F, Riehm H (1994) Konzeption und Zwischenergebnis der Therapiestudie ALL-BFM 90 zur Behandlung der akuten lymphoblastischen Leukämic bei Kindern und Jugendlichen: die Bedeutung des initialen Therapieansprechens in Blut und Knochenmark. Klin Pädiatr 206 : 208-221
24. Shah OV, Civin CI, Loken MR (1988) Flow cytometric analysis of human bone marrow. IV. Differential quantitative expression of T-200 common leukocyte antigen during normal hemopoiesis. J Immunol 140 : 1861-1867
25. Taetle R, Ostergaard H, Smedsrud M, Trowbridge I (1991) Regulation of CD45 expression in human leukemia cells. Leukemia 5 : 309-314
26. Tonks NK, Charbonneau H, Diltz CD, Fischer EH, Walsh KA (1988) Demonstration that the leucocyte common antigen CD45 is a protein tyrosine phosphatase. Biochemistry 27 : 1988-1994
27. Trowbridge IS (1991) CD45. A prototype for transmembrane protein tyrosine phosphatases. J Biol Chem 226 : 23517-23520