Autocrine FGF signaling is required for vascular smooth muscle cell survival in vitro

Journal of Cellular Physiology

Volumn 177, Issue 1, 1998, Pages 58-67

  Miyamoto, Tetsuya ^a   Leconte, Isabelle ^a   Swain, Judith L ^b   Fox, Jonathan C ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

ADENOVIRIDAE; ANIMALS; AORTA; APOPTOSIS; AUTOCRINE COMMUNICATION; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FLAVONOIDS; GENE EXPRESSION REGULATION, VIRAL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PROSTAGLANDINS F; RAS PROTEINS; RATS; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECOMBINANT FUSION PROTEINS;

ADENOVIRIDAE; ANIMALIA; MURINAE;

EID: 0031685330     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199810)177:1<58::AID-JCP6>3.0.CO;2-D     Document Type: Article

References (47)

1. Amaya, E., Musci, T.J., and Kirschner, M.W. (1991) Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66:257-270.
2. Arends, M.J., McGregor, A.H., Toft, N.J., Brown, E.J., and Wyllie, A.H. (1993) Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability. Br. J. Cancer 68:1127-1133.
3. Bellot, F., Crumley, G., Kaplow, J.M., Schlessinger, J., Jaye, M., and Dionne, C.A. (1991) Ligand-induced transphosphorylation between different FGF receptors. EMBO J. 10:2849-2854.
4. Bennett, M.R., Evan, G.I., and Schwartz, S.M. (1995) Apoptosis of rat vascular smooth muscle cells is regulated by p53-dependent and -independent pathways. Circ. Res. 77:266-273.
5. Bochaton-Piallat, M.L., Gabbiani, F., Redard, M., Desmouliere, A., and Gabbiani, G. (1995) Apoptosis participates in cellularity regulation during rat aortic intimal thickening. Am. J. Pathol. 146:1059-1064.
6. Burgering, B.M.T., and Coffer, P.J. (1995) Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602.
7. Burgess, W.H., and Maciag, T. (1989) The heparin-binding (fibroblast) growth factor family of proteins. Annu. Rev. Biochem. 58:575-606.
8. Campochiaro, P., Chang, M., Ohsata, M., Vinores, S., Nie, Z., Hjelmeland, L., Mansukhani, A., Basilico, C., and Zack, D. (1996) Retinal degeneration in transgenic mice with photoreceptor-specific expression of a dominant-negative fibroblast growth factor receptor. J. Neurosci. 16:1670-1688.
9. Casscells, W., Lappi, D.A., Olwin, B.B., Wai, C., Seigman, M., Speir, E.H., Sasse, J., and Baird, A. (1992) Elimination of smooth muscle cells in experimental restenosis: Targeting of fibroblast growth factor receptors. Proc. Natl. Acad. Sci. U. S. A. 89:7159-7163.
10. Chen, C.H., Zhang, J., and Ling, C.C. (1994) Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiat. Res. 139:307-315.
11. Cho, A., Courtman, D.W., and Langille, B.L. (1995) Apoptosis (programmed cell death) in arteries of the neonatal lamb. Circ. Res. 76:168-175.
12. Chow, R.L., Roux, G.D., Roghani, M., Palmer, M.A., Rifkin, D.B., Moscatelli, D.A., and Lang, R.A. (1995) FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens. Development 121:4383-4393.
13. Deng, C.X., Wynshaw-Boris, A., Shen, M.M., Daugherty, C., Ornitz, D.M., and Leder, P. (1994) Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 8:3045-3057.
14. Evan, G.I., Lewis, G.K., Ramsay, G., and Bishop, J.M. (1985) Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5:3610-3616.
15. Fernandez, A., Marin, M.C., McDonnell, T., and Ananthaswamy, H.N. (1994) Differential sensitivity of normal and Ha-ras-transformed C3H mouse embryo fibroblasts to tumor necrosis factor: Induction of bcl-2, c-myc, and manganese superoxide dismutase in resistant cells. Oncogene 9:2009-2017.
16. Ferrari, G., and Greene, L.A. (1994) Proliferative inhibition by dominant-negative Ras rescues naive and neuronally differentiated PC12 cells from apoptotic death. EMBO J. 13:5922-5928.
17. Fox, J.C., and Shanley, J.R. (1996) Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells. J. Biol. Chem. 271:12578-12584.
18. French, B.A., Mazur, W., Geske, R.S., and Bolli, R. (1994) Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors. Circulation 90:2414-2424.
19. Gardner, A.M., and Johnson, G.L. (1996) Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen activated protein kinase. J. Biol. Chem. 271:14560-14566.
20. Geng, Y.J., and Libby, P. (1995) Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme. Am. J. Pathol. 147:251-266.
21. Hanna, A.K., Fox, J.C., Neschis, D.G., Safford, S.D., Swain, J.L., and Golden, M.A. (1997) Antisense basic fibroblast growth factor gene transfer reduces neointimal thickening after arterial injury. J. Vasc. Surg. 25:320-325.
22. Hase, M., Araki, S., Kaji, K., and Hayashi, H. (1994) Classification of signals for blocking apoptosis in vascular endothelial cells. J. Biochem. 116:905-909.
23. Huang, J., Mohammadi, M., Rodrigues, G.A., and Schlessinger, J. (1995) Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis. J. Biol. Chem. 270:5065-5072.
24. Isner, J.M., Kearney, M., Bortman, S., and Passeri, J. (1995) Apoptosis in human atherosclerosis and restenosis. Circulation 91:2703-2711.
25. Jaye, M., Schlessinger, J., and Dionne, C.A. (1992) Fibroblast growth factor receptor tyrosine kinases: Molecular analysis and signal transduction. Biochim. Biophys. Acta 1135:185-199.
26. Kato, S., Shanley, J.R., and Fox, J.C. (1996) Serum stimulation, cell-cell interactions, and extracellular matrix independently influence smooth muscle cell phenotype in vitro. Am. J. Pathol. 149:687-697.
27. Klambt, C., Glazer, L., and Shilo, B.Z. (1992) Breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. Genes Dev. 6:1668-1678.
28. Leszczynski, D., Zhao, Y., Luokkamaki, M., and Foegh, M.L. (1994) Apoptosis of vascular smooth muscle cells: Protein kinase C and oocoprotein Bcl-2 are involved in regulation of apoptosis in non-transformed rat vascular smooth muscle cells. Am. J. Pathol. 145:1265-1270.
29. Li, Y., Basilico, C., and Mansukhani, A. (1994) Cell transformation by fibroblast growth factors can be suppressed by truncated fibroblast growth factor receptors. Mol. Cell. Biol. 14:7660-7669.
30. Lindner, V., and Reidy, M.A. (1991) Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc. Natl. Acad. Sci. U. S. A. 88:3739-3743.
31. Lindner, V., and Reidy, M.A. (1993) Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study. Circ. Res. 73:589-595.
32. Lipson, S.M., Poshni, I.A., Ashley, R.L., Grady, L.J., Ciamician, Z., and Teichberg, S. (1993) Presumptive identification of common adenovirus serotypes by the development of differential cytopathic effects in the human lung carcinoma (A549) cell culture. FEMS Microbiol. Lett. 113:175-182.
33. Mansukhani, A., Moscatelli, D., Talarico, D., Levytska, V., and Basilico, C. (1990) A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF. Proc. Natl. Acad. Sci. U. S. A. 87:4378-4382.
34. May, W.S., Tyler, P.G., Ito, T., Armstrong, D.K., Qatsha, K.A., and Davidson, N.E. (1994) Interleukin-3 and bryostatin-1 mediate hyperphosphorylation of BCL2 alpha in association with suppression of apoptosis. J. Biol. Chem. 269:26865-26870.
35. Peters, K., Werner, S., Liao, X., Wert, S., Whitsett, J., and Williams, L. (1994) Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J. 13:3296-3301.
36. Reichman-Fried, M., Dickson, B., Hafen, E., and Shilo, B.Z. (1994) Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration. Genes Dev. 8:428-439.
37. Reidv, M.A. (1992) Factors controlling smooth-muscle cell proliferation. Arch. Pathol. Lab. Med. 116:1276-1280.
38. Reidy, M.A., Fingerle, J., and Lindner, V. (1992) Factors controlling the development of arterial lesions after injury. Circulation 86(Suppl III):43-46.
39. Renaud, F., Oliver, L., Desset, S., Tassin, J., Romquin, N., Courtois, Y., and Laurent, M. (1994) Up-regulation of aFGF expression in quiescent cells is related to cell survival. J. Cell. Physiol. 158:435-443.
40. Robinson, M.L., MacMillan-Crow, L.A., Thompson, J.A., and Overbeek, P.A. (1995) Expression of a truncated FGF receptor results in defective lens development in transgenic mice. Development 121:3959-3967.
41. Saint-Jeannet, J.P., Thiery, J.P., and Koteliansky, V.E. (1994) Effect of an inhibitory mutant of the FGF receptor on mesoderm-derived alpha-smooth muscle actin-expressing cells in Xenopus embryo. Dev. Biol. 164:374-382.
42. Shi, E., Kan, M., Xu, J., Wang, F., Hou, J., and McKeehan, W.L. (1993) Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants. Mol. Cell. Biol. 13:3907-3918.
43. Tamm, I., Kikuchi, T., and Zychlinsky, A. (1991) Acidic and basic fibroblast growth factors are survival factors with distinctive activity in quiescent BALB/c 3T3 murine fibroblasts. Proc. Natl. Acad. Sci. U. S. A. 88:3372-3376.
44. Ueno, H., Gunn, M., Dell, K., Tseng, A., Jr., and Williams, L. (1992) A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor. J. Biol. Chem. 267:1470-1476.
45. Wang, H.G., Millan, J.A., Cox, A.D., Der, C.J., Rapp, U.R., Beck, T., Zha, H.B., and Reed, J.C. (1995) R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism. J. Cell Biol. 129:1103-1114.
46. Yang, Y., Raper, S.E., Cohn, J.A., Engelhardt, J.F., and Wilson, J.M. (1993) An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer. Proc. Natl. Acad. Sci. U. S. A. 90:4601-4605.
47. Zhang, W.W., Koch, P.E., and Roth, J.A. (1995) Detection of wild-type contamination in a recombinant adenoviral preparation by PCR. Biotechniques 18:444-447.